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Composition containing oligopeptide and D-glucosamine hydrochloride for patients with bone injury

A technology of glucosamine hydrochloride and oligopeptides, which is applied in food science, application, food preparation, etc., can solve the problems of no particularly outstanding effects, and achieve the effect of improving biomechanical properties

Active Publication Date: 2012-08-22
山东鲁健生物医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, this special dietary food formula containing short peptides for patients with bone injuries has no particularly prominent effect on improving the biomechanical properties of compression and fracture in osteoporosis patients through synergistic treatment with drugs

Method used

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  • Composition containing oligopeptide and D-glucosamine hydrochloride for patients with bone injury

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Example 1 Preparation of nutritional granules

[0028] Take 100g of peach kernels, 280g of mushrooms and 250g of dried tangerine peels and mix them, add water to decoct twice, the first time adding water is 8 times the weight of the medicinal material, decocting for 1h, the second time adding water is 6 times the weight of the medicinal material, and decocting for 1h , Combine the decoction, filter, and concentrate the filtrate to a relative density of 1.10 (65°C). Add appropriate amount of ethanol to make the alcohol content (volume fraction) reach 65%, stir, let stand for 24 hours, filter, the filtrate recovers ethanol and concentrates to the extract with a relative density of 1.20 (65°C), spray-dried (condition is air intake) The temperature is 100°C, the air outlet temperature is 80°C, the material temperature is 70°C, the atomization pressure is 0.2 MPa, and the spray speed is 5 ml / s.), crushed into dry extract powder to obtain the Chinese medicine extract.

[0029] Th...

Embodiment 2

[0032] Example 2 Preparation of nutritional granules

[0033] Take the traditional Chinese medicine extract prepared in Example 1 and prepare the granules of the present invention according to the following prescription:

[0034] Marine collagen peptide1g Marine osteogenic peptide3g D-glucosamine hydrochloride0.5g Chinese medicine extract 4g

[0035] Preparation process: Weigh the above components, then add appropriate dextrin, soluble starch and sucrose and other one or more of the auxiliary materials, wet with an appropriate amount of 80% ethanol, make soft materials, pass through a 14-mesh sieve, and granulate, 50-80 Dried at ℃, and sized at 60 mesh to obtain granules.

Embodiment 3

[0036] Example 3 Preparation of nutritional powder

[0037] Take 50g of peach kernels, 320g of shiitake mushrooms and 200g of dried tangerine peels and mix them, add water to decoct twice, the first time adding water is 8 times the weight of the medicinal material, decocting for 1h, the second time adding water is 6 times the weight of the medicinal material, and decocting for 1h , Combine the decoction, filter, and concentrate the filtrate to a relative density of 1.10 (65°C). Add appropriate amount of ethanol to make the alcohol content (volume fraction) reach 65%, stir, let stand for 24 hours, filter, the filtrate recovers ethanol and concentrates to the extract with a relative density of 1.20 (65°C), spray-dried (condition is air intake) The temperature is 100°C, the air outlet temperature is 80°C, the material temperature is 70°C, the atomization pressure is 0.2 MPa, and the spray speed is 5 ml / s.), crushed into dry extract powder to obtain the Chinese medicine extract.

[00...

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Abstract

The invention discloses a composition containing oligopeptide and D-glucosamine hydrochloride for patients with bone injury. The composition contains oligopeptide, D-glucosamine hydrochloride and a traditional Chinese medicine extract, wherein the oligopeptide is the mixture of marine collagen peptide and marine ossein peptide, and the traditional Chinese medicine extract is the extract of peach kernel, lentinus edodes and dried orange peel. The composition not only can maintain the nutritive equilibrium of patients with bone injury, but also can improve the biomechanical characteristics of compression resistance and fracture resistance of patients with osteoporosis.

Description

Technical field [0001] The invention relates to a food formula, in particular to a composition containing oligopeptides and D-glucosamine hydrochloride for bone injury patients to eat, and belongs to the technical field of food health care. Background technique [0002] Fracture refers to a disease in which bone is partially or completely broken due to trauma or pathology. The main clinical manifestations are: localized pain and tenderness in the fracture, local swelling and ecchymosis, partial loss of limb function, and complete bone deformity and abnormal movement. [0003] In our country, fracture has become a common and frequently-occurring disease. In addition to fractures caused by accidents, fractures caused by osteoporosis are more common. Osteoporosis is a systemic disease in which the bone mass is significantly reduced, the tiny structure of bone is destroyed, the fragility of bone is increased, and the risk of fracture is increased. The ideal osteoporosis treatment dr...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K38/39A23L1/09
Inventor 尹作梅于红王宗继焦念强苗涛何强
Owner 山东鲁健生物医药科技有限公司
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