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Chinese medicine composite with sun-screening function and preparation method and application of extract thereof

A technology of composition and extract, which is applied in the field of compounded traditional Chinese medicine composition to achieve excellent sun protection function, inhibition of tyrosinase activity, and good effect of scavenging free radicals

Inactive Publication Date: 2012-04-11
广州市有喜化妆品有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are few reports on the sunscreen performance of traditional Chinese medicine extracts. Invention patent ZL200810124632.3 discloses a sunscreen containing Sophora japonica, honeysuckle and peony as sunscreen ingredients and its preparation method

Method used

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  • Chinese medicine composite with sun-screening function and preparation method and application of extract thereof
  • Chinese medicine composite with sun-screening function and preparation method and application of extract thereof
  • Chinese medicine composite with sun-screening function and preparation method and application of extract thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] Embodiment 1 sunscreen effect evaluation experiment

[0017] 1. Sample preparation

[0018] The extract of the above-mentioned traditional Chinese medicine composition was dissolved in dimethyl sulfoxide to prepare a sample solution with a concentration of 0.1%, and the following test was carried out.

[0019] 2. Anti-ultraviolet effect evaluation test

[0020] Scan the above sample in the wavelength range of 280-320nm, measure the light transmittance at each wavelength, and calculate the average transmittance. And calculate the average UV absorption rate according to formula (1). Those with an ultraviolet absorption rate above 80% can be considered to have a sunscreen effect; those with an ultraviolet absorption rate above 90% can be considered to have a strong sunscreen effect.

[0021] Average UV absorbance (%)=100%-average light transmittance. (1)

[0022] 3. Evaluation test on the effect of inhibiting tyrosinase activity

[0023] Accurately absorb the sample ...

Embodiment 2

[0039] The preparation of embodiment 2 Chinese medicine composition (I) and extract thereof

[0040] Take 100g each of alpinia officinalis, basil, grass fruit, linden flower, sage, and coltsfoot flower, crush them, pass through a 40-mesh sieve, mix evenly, add 4.2kg of ethanol aqueous solution with a mass fraction of 50%, heat and reflux for 60min, repeat Extracted 3 times, combined the extracts, decolorized with activated carbon, filtered, and the filtrate was concentrated under reduced pressure until it was in the form of an extract.

[0041] According to the experiment, the average ultraviolet absorption rate of the traditional Chinese medicine composition (I) is 95.2, the inhibition rate to tyrosinase is 43.2%, and the free radical scavenging rate is 52.4%.

Embodiment 3

[0042] The preparation of embodiment 3 Chinese medicine composition (II) and extract thereof

[0043] Take 50g of alpinia, 120g of basil, 100g of grass fruit, 150g of linden flower, 80g of sage, and 100g of coltsfoot flower, pulverize them, pass through a 40-mesh sieve, mix evenly, add 5.4kg of ethanol aqueous solution with a mass fraction of 50%, and heat to reflux Extract for 90 minutes, repeat the extraction twice, combine the extracts, decolorize with activated carbon, filter, and concentrate the filtrate under reduced pressure until it is in the form of extract.

[0044]According to the experiment, the average ultraviolet absorption rate of the traditional Chinese medicine composition (II) is 93.5, the inhibition rate to tyrosinase is 41.7%, and the free radical scavenging rate is 48.2%.

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Abstract

The invention discloses a Chinese medicine composite with a sun-screening function and a preparation method and application of an extract thereof in sun-screening cosmetics. The Chinese medicine composite comprises alpinia japonica, basil, Amomum tsao-ko, linden flower, sage and tussilago. The extract of the Chinese medicine composite is prepared by the following steps of: crushing the Chinese medicinal raw materials, screening, adding an extracting solvent (such as water, ethanol and ethanol aqueous solution), heating and refluxing for extracting, decoloring extracting solution with activated carbon, filtering, and finally concentrating extracting solution into an extractum shape under reduced pressure. The extract of the Chinese medicine composite can absorb ultraviolet rays effectivelyand has the effects of clearing away radicals very well and restraining the activity of tyrosinase, is a safe and efficient sun-screening agent and can be applied to sun-screening cosmetics.

Description

technical field [0001] The invention relates to a compounded traditional Chinese medicine composition. The extract of the composition has a sunscreen function and can be used in sunscreen cosmetics. Background technique [0002] Ultraviolet light is a section of solar radiation with a wavelength of 230-400nm. According to the wavelength, it is divided into UVA (320nm-400nm), UAB (290nm-320nm) and UVC (200nm-290nm). Only a very low dose of UVA can reach the earth. And a very small dose of UVB, while UVC cannot reach the surface of the earth, so sunscreen is mainly anti-UVA and UAB. UVB is the most harmful to the human body. It is the main band of photobiological effects caused by solar radiation on the skin, causing skin erythema and stimulating skin cancer cells. UVA is the most penetrating to the skin and mainly causes skin tanning. As the harm of ultraviolet rays to the human body and the incidence of skin cancer are increasing in the world, people are paying more and mo...

Claims

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Application Information

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IPC IPC(8): A61K8/97A61Q17/04
Inventor 龚盛昭
Owner 广州市有喜化妆品有限公司
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