Medicine composition for treating cerebrovascular and cardiovascular diseases as well as preparation method and application thereof

A composition and cardiovascular technology, applied in cardiovascular system diseases, drug combinations, pharmaceutical formulations, etc., can solve the problems of lack of Chinese patent medicine and western medicine, depletion of human qi, blood and body fluid, and unfavorable conditions, and achieve good curative effect.

Inactive Publication Date: 2012-04-11
CHENGDU UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The ingredients of these aromatic medicines are very depleting of the body's qi, blood and body fluids, and taking them for a long time is not good for the condition
At the same time, cerebrovascular and cardiovascular diseases need to continue to take effective treatment after first aid, and after the "emergency", follow-up treatment must be followed up as soon as possible, which is the most important and permanent treatment. Clinically, It's just that Western medicine lacks effective varieties in this area, and related Chinese patent medicines are not common, especially Chinese patent medicines and Western medicines that treat cerebrovascular and cardiovascular diseases at the same time are seriously lacking

Method used

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  • Medicine composition for treating cerebrovascular and cardiovascular diseases as well as preparation method and application thereof
  • Medicine composition for treating cerebrovascular and cardiovascular diseases as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] The preparation of embodiment 1 pharmaceutical composition of the present invention

[0030] Raw materials: ginseng total saponins 80g, Panax notoginseng saponins 100g, tanshinone extract 100g, salvianolic acid A 50g, acetaloflavone 150g, Chuanxiong extract 120g, Achyranthes bidentata extract 180g, natural hirudin 120g, Cyperus cyperi 120g of the extract, after sieving with 80 meshes, mix the ingredients uniformly for later use; take polyethylene glycol 6000, the ratio of its dosage to the total dosage of raw materials is 65:35W / W, after melting, mix the raw materials homogeneously Add it into the molten matrix, keep it warm at 75-85°C, use a dropping pill machine, the inner / outer diameter of the dropping port: 3.0 / 4.0mm, the dropping speed 40-50 drops / min, drop it into the coolant simethicone, and collect the dropping pills , the average pill weight is 51.8 mg or 52 mg, containing about 18 mg of the extract of the formula.

[0031] For the preparation method and quali...

Embodiment 2

[0040] The preparation of embodiment 2 pharmaceutical composition of the present invention

[0041] Take ginseng total saponins 8g, Panax notoginseng saponins 10g, tanshinone extract 10g, salvianolic acid A 5g, acetaloflavone 15g, Chuanxiong extract 12g, Achyranthes bidentata extract 18g, hirudin 12g, Rhizoma Cyperus extract 12g, After passing through a 60-80 mesh sieve, add an appropriate amount of microcrystalline cellulose, mix well, and pack into capsules.

Embodiment 3

[0042] The preparation of embodiment 3 pharmaceutical composition of the present invention

[0043] Take 5.6g of total ginsenosides, 13g of total saponins of Panax notoginseng, 13g of tanshinone extract, 6.5g of salvianolic acid A, 19.5g of acetaloflavone, 15.6g of Chuanxiong extract, 23.4g of Achyranthes bidentata extract, 15.6g of hirudin, Cyperus cyperus extract 1.56g, add appropriate amount of dextrin and soluble starch, mix well, and prepare granules.

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Abstract

The invention discloses a medicine composition for treating cerebrovascular and cardiovascular diseases as well as a preparation method and an application of the medicine composition. The medicine composition can resist thrombosis and blood stasis and can be used treating cerebrovascular diseases such as cerebral ischemia, cerebral thrombosis, cerebral embolism and the like and cardiovascular diseases such as coronary heart disease, hypertension, hyperlipidemia, atherosclerosis, atherosclerosis, arrhythmia, heat failure, angina, myocardial infarction and the like. The medicine composition is especially used for continuously treating patients with cerebrovascular and cardiovascular diseases after emergency treatment and has good curative effects, and a new choice is provided for clinical medication.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating cerebrovascular and cardiovascular diseases, a preparation method and application thereof. Background technique [0002] Cerebrovascular and cardiovascular diseases have become the number one killer of human health, and their morbidity and mortality have already surpassed tumor diseases to rank first. Most patients need to take medicine for life. Cerebrovascular disease is a group of diseases that cause brain tissue damage due to brain blood supply disorders. It mainly affects middle-aged and elderly patients. Most patients present with hemiplegia and speech impairment. Most of these diseases are caused by vascular wall lesions atherosclerosis, hyperlipidemia, diabetes, hypertension, thrombocytosis, coronary heart disease, and poisoning. Common cerebrovascular diseases include transient ischemic attack, cerebral thrombosis, cerebral infarction, and stroke. In the International Classif...

Claims

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Application Information

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IPC IPC(8): A61K38/58A61K36/8905A61P9/04A61P9/06A61P9/10A61P9/12A61K31/216
Inventor 李戎吴纯洁
Owner CHENGDU UNIV OF TRADITIONAL CHINESE MEDICINE
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