Polymer vesica with antibacterial nano silver deposited on surface and preparation method thereof

A technology of surface deposition and nano-silver, which is applied in the direction of medical preparations and pharmaceutical formulas with non-active ingredients, can solve the problems of complex preparation methods, inconvenient use, complex nano-silver reagents and coating components, etc., and achieve simple preparation methods, Wide range of effects
CN102432974AInactive Publication Date: 2012-05-02TONGJI UNIV
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Patent Information

Authority / Receiving Office
CN Β· China
Patent Type
Applications(China)
Current Assignee / Owner
TONGJI UNIV
Publication Date
2012-05-02
Estimated Expiration
Not applicable Β· inactive patent

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Abstract

The invention belongs to the field of nano biological medical materials and particularly relates to polymer vesica with the surface deposited with antibacterial nano silver and a preparation method thereof. Amphipathic block polymers are self-assembled by a cosolvent method to form the vesica, and then the nano silver is generated in situ on the surface of the vesica. The polymer vesica has biocompatibility and has certain temperature and pH sensitivity; a cavity structure of the vesica can wrap various medicines; and simultaneously, due to the existence of the nano silver, the vesica also has the curative effects of sterilization and bactriostasis.
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Description

technical field

[0001] The invention belongs to the field of macromolecular nano biomedical materials, in particular to a polymer vesicle with antibacterial nano silver deposited on the surface and a preparation method thereof. Background technique

[0002] In recent years, the preparation of polymer vesicles by self-assembly technology has attracted more and more attention from scientists from all over the world, because the polymer molecules that make up the vesicles will have corresponding shapes, The change in structure or composition, therefore, endows polymersomes with many excellent properties. Based on this, polymersomes have a wide range of application prospects in many fields, such as drug loading, gene carriers, biomineralization Templates, microreactors, biological scaffolds, etc.

[0003] Amphiphilic block polymers can self-assemble in water to form vesicles with bilayer membranes. Compared with liposome vesicles, polymer vesicles have greatly improved mechanic...

Claims

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