Naphthylacetic acid and naphthylacetic acid saline dispersible granules/or tablets and preparation method thereof
A technology of naphthalene acetate and naphthalene acetic acid, applied in botany equipment and methods, biocides, animal repellants, etc., can solve the problems of easy phytotoxicity, inaccurate measurement, inaccurate measurement, etc., and achieve stable storage Good performance, accurate measurement, fast disintegration
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Embodiment 15
[0035] The preparation of embodiment 15% naphthalene acetic acid water-dispersible granules
[0036] The selection and proportioning of the original drug and auxiliary agents are: 80% naphthaleneacetic acid original drug 6.5% (5.0%), the dispersant is 2.0% sodium methylene bismethyl naphthalene sulfonate, 4.0% calcium lignosulfonate, Wetting agent sodium lauryl sulfate 2.0%, disintegrating agent is ammonium sulfate 8.0%, binder is starch 5.0%, filler is attapulgite to make up 100%
[0037] According to the above proportions, the dosage of each component is calculated, weighed, and mixed evenly; the formula is granulated by ultrafine / jet milling, dried, granulated, and selected. Product testing is carried out according to the quality control indicators of water-dispersible granules, including the content of active ingredients, wetting time, disintegration time limit, suspension rate, foaming property, sieve analysis, shedding rate, pH range and thermal storage stability, etc. ...
Embodiment 1
[0043] The performance indicators of the NAA water-dispersible granules prepared in Example 1 are: NAA content 5.1%, wettability qualified (18 seconds), disintegration time limit (47 seconds), foaming performance qualified (19 milliliters), moisture content 1.2% , pH value 6.8, suspension rate 83%, shedding rate 0.9%, sieve analysis 99%, thermal storage stability qualified, active ingredient decomposition rate 0.8%.
Embodiment 2
[0044] The preparation of embodiment 2 5% naphthalene acetic acid water dispersible tablet
[0045] The selection and ratio of original medicine and auxiliary agent is: 80% naphthaleneacetic acid original medicine 6.5% (5.0%), dispersant is naphthalene sulfonate formaldehyde condensate 3.0%, calcium lignosulfonate 3.0%, wetting agent Sodium lauryl sulfate 2.0%, disintegrant is microcrystalline cellulose sodium 17.0%, binding agent is polyvinyl alcohol 5.0%, filler is talcum powder and makes up 100%.
[0046] According to the above proportions, the dosage of each component is calculated, weighed, and mixed evenly; the formula is granulated by ultrafine / jet milling, dried, pressed into tablets, and selected. Product testing is carried out according to the quality control indicators of water-dispersible tablets, including the content of active ingredients, disintegration time limit, suspension rate, foaming property, sieve analysis, powder and fragment rate, pH range and thermal ...
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