Bacterial compositions for prophylaxis and treatment of degenerative disease

A composition and bacterial technology, applied in the direction of bacteria, metabolic diseases, blood diseases, etc., can solve problems such as side effects, physical discomfort, and flushing of the whole body
CN102481322AInactive Publication Date: 2012-05-30MICROPHARMA
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
MICROPHARMA
Publication Date
2012-05-30
Estimated Expiration
Not applicable · inactive patent

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Abstract

The disclosure provides an oral composition for reducing serum cholesterol, serum lipids, body fat, or atherogenic index or for prophylaxis or treatment of atherosclerosis, cardiovascular or cerebrovascular diseases, comprising a highly bsh active bacteria, isolate or supernatant thereof; wherein the highly bsh active bacteria degrades >50[mu]mol glycodeoxycholic acid (GDCA) / gram / hour and >2[mu]mol taurodeoxycholic acid (TDCA) / gram / hour when measured over 1 hour and 5 hours, respectively, or degrades >65 [mu]mol GDCA / g / hr and >7 [mu]mol TDCA / g / hr when measured over 30 minutes.
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Description

[0001] Related Patent Applications

[0002] This application claims the benefit of and priority to co-pending US Provisional Patent Application No. 61 / 174,740, filed May 1, 2009, the entire disclosure of which is incorporated herein by reference in its entirety. technical field

[0003] The present disclosure relates to an improved oral composition of bacteria with high bsh activity, its isolate or supernatant, and the process for preparing the improved composition. The present disclosure also relates to methods and uses of the improved oral composition, including reducing serum cholesterol, blood lipid, body fat or atherosclerosis index, and preventing and treating atherosclerosis, cardiovascular or cerebrovascular diseases. technical background

[0004] Hypercholesterolemia and Coronary Artery Disease

[0005] Coronary artery disease (CAD) is the leading cause of death in Western countries, the most common heart disease and the most common cause of sudden death. Clinical...

Claims

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