OLED (Organic Light-Emitting Diode)- and OPD (Organic Photodetector)-based cascading vertical integration capillary electrophoresis chip

Abstract

The invention discloses an OLED (Organic Light-Emitting Diode)- and OPD (Organic Photodetector)-based cascading vertical integration capillary electrophoresis chip. The OLED- and OPD-based cascading vertical integration capillary electrophoresis chip comprises arrayed organic thin-film light sources (OLEDs), a polarizer, a multi-channel capillary electrophoresis chip, a polarization detector and arrayed organic thin-film detectors (OPDs), wherein the OLEDs, the polarizer, the multi-channel capillary electrophoresis chip, the polarization detector and the OPDs are sequentially placed in a parallel and cascading manner; and an upper part and a lower part of each electrophoresis channel detection position respectively correspond to the single OLED and the single OPD. According to the OLED- and OPD-based cascading vertical integration capillary electrophoresis chip, the OLEDs and the OPDs which are made from organic photoelectric materials respectively are adopted, therefore, the easy integration with the multi-channel capillary electrophoresis chip is achieved; with the adoption of planar structural parallel cascading arrangement, the distance between every two devices is small, the optical length of a light path in transmission along the vertical direction is short, the optical loss is effectively lowered, the improvement of system sensitivity is facilitated, and the accuracy in detection is improved through the controlling of the diameter of an exciting light beam by a pinhole; and polaroids which are arranged in a mutually-vertical manner are used for light-filtering, excitation light and stray light are effectively filtered out, therefore, the OLED- and OPD-based cascading vertical integration capillary electrophoresis chip is applicable to a detection system with wider spectral range.

Description

technical field [0001] The invention belongs to the technical field of chemical analysis. According to the laser-induced fluorescence detection principle of capillary electrophoresis chips, a stacked vertical integrated capillary electrophoresis chip based on OLED (Organic Light-Emitting Diode) and OPD (Organic Photodetector) is proposed for use in Analysis and detection of multi-channel capillary electrophoresis chip. Background technique [0002] Miniaturized total analysis systems (μTAS) is a miniature biochemical analysis system that integrates all analysis functions into a chip based on micro-electromechanical processing technology, also known as lab-on-a-chip. . The current research focus is on microfluidic chips based on microfluidic technology, that is, to build a chemical or biological laboratory on a chip of several square centimeters, integrating sample preparation, reaction, and separation involved in the fields of chemistry and biology. , Detection, cell cult...

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Problems solved by technology

The disadvantage of the above method is that the mechanical device or optical system is bulky, which is extremely disproportionate to the small capillary electrophoresis chip, and it is difficult to realize the volume integration, miniaturization and portability of the entire detection system

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