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Medicinal composition with antipyretic, anti-inflammatory and analgesic effects and preparation method thereof

A composition and drug technology, applied in the direction of drug combination, medical preparations containing active ingredients, antipyretics, etc., can solve the problem that severe patients are difficult to work

Inactive Publication Date: 2012-07-11
SHENZHEN TONIC MEDICINE TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Oral ulcers, periodontitis, and headaches are also common clinical diseases. The etiology of these diseases is complex, and pain is an important clinical s

Method used

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  • Medicinal composition with antipyretic, anti-inflammatory and analgesic effects and preparation method thereof
  • Medicinal composition with antipyretic, anti-inflammatory and analgesic effects and preparation method thereof
  • Medicinal composition with antipyretic, anti-inflammatory and analgesic effects and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0204] [Example 1] Preparation of granules of the pharmaceutical composition of the present invention

[0205] Weigh 20g of raw gypsum, 10g of Rhizoma Chuanxiong and / or 15g of Angelica dahurica, and set aside.

[0206] Extract Chuanxiong and / or Angelica dahurica with 8 times the amount of 70% ethanol for 3 times, each time for 1 hour, filter, combine the filtrate, recover the ethanol under reduced pressure, concentrate to a relative density of 1.05-1.15 (70-85°C thermal measurement), static Placed, filtered, and the filtrate was concentrated under reduced pressure below 60°C to form a thick paste, and dried to obtain component 1.

[0207] Add raw gypsum to 10 times the amount of water and decoct 3 times, each time for 1 hour, filter, combine all filtrates, concentrate to a relative density of 1.05-1.15 (70-85°C thermal measurement), let stand, filter, concentrate and dry the filtrate to obtain Component 2.

[0208] Combine component 1 and component 2, add appropriate amount ...

Embodiment 2

[0209][embodiment 2] tablet preparation of pharmaceutical composition of the present invention

[0210] Weigh 20g of raw gypsum, 10g of Rhizoma Chuanxiong, 15g of Angelica dahurica, 10g of Cimicifuga, and 15g of Achyranthes bidentata, and set aside.

[0211] Extract Rhizoma Chuanxiong, Angelica dahurica, Achyranthes bidentata or Achyranthes bidentata plus 8 times the amount of 60% ethanol for 3 times, each time for 1 hour, filter, combine the filtrates, recover ethanol under reduced pressure, and dry under reduced pressure below 60°C to obtain component 1.

[0212] Add raw gypsum and Cimicifuga 10 times the amount of water to decoct 3 times, each time for 1 hour, filter, combine all filtrates, concentrate to a relative density of 1.05-1.15 (70-85°C heat test), let stand, filter, concentrate the filtrate, Dry to obtain component 2.

[0213] Combine component 1 and component 2, pulverize, mix evenly, and press into tablets to obtain the product.

Embodiment 3

[0214] [embodiment 3] capsule preparation of pharmaceutical composition of the present invention

[0215] Weigh raw gypsum 20g, Chuanxiong 10g, Angelica dahurica 15g, Cimicifuga 10g, Chuan Achyranthes bidentata 15g, Rehmannia glutinosa 15g, set aside.

[0216] Extract Rhizoma Chuanxiong, Angelica dahurica, Rhizoma Achyranthes Radix, and Rehmannia glutinosa plus 8 times the amount of 70% ethanol for 3 times, each time for 1 hour, filter, combine the filtrates, recover ethanol under reduced pressure, and dry under reduced pressure below 60°C to obtain component 1.

[0217] Add raw gypsum and Cimicifuga to 10 times the amount of water and decoct 3 times, each time for 1 hour, filter, combine the filtrate, concentrate to a relative density of 1.05-1.15 (heat measurement at 70-85°C), let stand, filter, concentrate the filtrate, and dry , get component 2.

[0218] Combine component 1 and component 2, pulverize into powder, mix evenly, pass through a No. 6 sieve, fill in hard capsul...

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Abstract

The invention discloses a medicinal composition with antipyretic, anti-inflammatory and analgesic effects and a preparation method thereof, and belongs to the field of Chinese medicines. The medicinal composition comprises the following Chinese herbal medicines in part by weight: 10 to 50 parts of gypsum serving as a monarch medicine and 5 to 15 parts of szechuan lovage rhizome serving as a minister medicine or 5 to 15 parts of szechuan lovage rhizome and 5 to 25 parts of angelica dahurica which serve as the minister medicine. The medicinal composition can be prepared into any common preparation for oral administration; and on the basis of the monarch medicine and the minister medicine, different adjuvant medicines are added according to the severe degree or duration of illness to exert a better curative effect. The medicinal composition has the obvious antipyretic, anti-inflammatory and analgesic effects, can be widely used for treating multiple diseases such as fever, inflammation and pain, is particularly suitable for treating diseases of fever and pain in heads and bodies which are caused by cold, dental ulcer or dental arthritis or various headaches and the like or diseases such as excessive heat in qi system of yangming, heat stagnation of yangming, deficiency fire of spleen and stomach, headaches and the like in traditional Chinese medical science, and has the characteristics of high efficiency, quick response, relapse prevention of the illness after medicine withdrawal and the like.

Description

[0001] This application is a divisional application of the invention patent application of "a pharmaceutical composition with antipyretic, anti-inflammatory and analgesic effects and its preparation method". The original application date is 2008.03.25; the application number is: 200810065869.9. [technical field] [0002] The invention relates to a pharmaceutical composition with antipyretic, anti-inflammatory and analgesic effects and a preparation method thereof, belonging to the field of traditional Chinese medicines. [Background technique] [0003] Cold is a common disease. Fever and head and body pain are the main symptoms. Western medicine believes that it is mostly caused by viral infection. However, the current antiviral drugs are not effective, and the commonly used antipyretic and analgesic drugs can only temporarily control the symptoms. , it is difficult to completely solve the pain. Although there are many types of Chinese patent medicine preparations for treatin...

Claims

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Application Information

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IPC IPC(8): A61K36/236A61P29/00A61K33/06
Inventor 不公告发明人
Owner SHENZHEN TONIC MEDICINE TECH
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