Gynecological sugar-free gynaecopathia treating particle and preparation method thereof

A granule, sugar-free technology, applied in the field of medicines for treating gynecological diseases, can solve the problems of high sugar content, waste of auxiliary material resources, etc., and achieve the effects of high safety, reduction of auxiliary material dosage, and reasonable formulation.

Inactive Publication Date: 2012-07-11
武汉哈瑞医药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Fukangbao originated from Xiongguijiaoai Decoction in the "Jinbian Yaolue" written by Zhang Zhongjing, a medical sage in the Han Dynasty. However, the existing Fukangbao preparations all contain sugar, which has great limitations in clinical use, especially for diabetics, obese patients and those who do not like Beauty ladies who eat too much sugar have great limitations
[0004] In addition, the existing Fukangbao preparations all contain sugar and the sugar content is very high, which requires the use of a large amount of excipients, wasting the resources of excipients

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Gynecology sugar-free Fukangbao Granules, composed of Rehmannia glutinosa 115g, Chuanxiong 46g, Baishao 93g, Artemisia argyi 46g, Angelica 69g, Licorice 46g, Ejiao 69g, Dextrin 200g, Lactose 160g, Dextrin 200g, Lactose 160g gram, stevioside 0.3 gram is prepared.

[0030] Its specific preparation method: add water to extract volatile oil from Angelica 69g, Artemisia argyi 93g, Chuanxiong 46g, add water to decoct medicinal dregs and white peony 93g, Rehmannia glutinosa 115g, and licorice 46g, decoct twice for 3 hours for the first time, 2 hours for the second time, and combine The decoction was left to stand for 18 hours, filtered, and the filtrate was concentrated into an extract with a relative density of 1.20 at 60°C. 69g of donkey-hide gelatin is pulverized, and the extract is added with pulverized donkey-hide gelatin powder and 200 grams of dextrin, 160 grams of lactose, and 0.3 grams of stevia to make granules, dry, let cool, spray the above-mentioned extracted vola...

Embodiment 2

[0032] Fuke sugar-free Fukangbao granules are prepared from 115g rehmannia glutinosa, 46g Chuanxiong 46g, 93g white peony, 46g mugwort leaves, 69g angelica, 46g licorice, 69g donkey-hide gelatin, 200g dextrin, 200g mannitol, and 0.3g stevia to make.

[0033] Its specific preparation method: add water to extract volatile oil from Angelica 69g, Artemisia argyi 93g, Chuanxiong 46g, add water to decoct medicinal dregs and white peony 93g, Rehmannia glutinosa 115g, and licorice 46g, decoct twice for 3 hours for the first time, 2 hours for the second time, and combine The decoction was left to stand for 21 hours, filtered, and the filtrate was concentrated into an extract with a relative density of 1.35 at 45°C. 69g of donkey-hide gelatin is pulverized, and the extract is added with pulverized donkey-hide gelatin powder, 200 grams of dextrin, 200 grams of mannitol, and 0.3 grams of steviol to make granules, dry, let cool, spray the above-mentioned extracted volatile oil, mix well, a...

Embodiment 3

[0035] Fuke sugar-free Fukangbao granules are prepared from 115g rehmannia glutinosa, 46g Chuanxiong 46g, 93g white peony, 46g mugwort leaves, 69g angelica, 46g licorice, 69g donkey-hide gelatin, 600g dextrin, and 0.3g aspartame.

[0036] Its specific preparation method: add water to extract volatile oil from Angelica 69g, Artemisia argyi 93g, Chuanxiong 46g, add water to decoct medicinal dregs and white peony 93g, Rehmannia glutinosa 115g, and licorice 46g, decoct twice for 3 hours for the first time, 2 hours for the second time, and combine The decoction is left to stand for 18 to 24 hours, filtered, and the filtrate is concentrated into an extract with a relative density of 1.40 at 60°C. 69g of donkey-hide gelatin is crushed, and the extract is added with crushed donkey-hide gelatin powder, 600 grams of dextrin, and 0.3 grams of aspartame to make granules, dried, cooled, sprayed with the above-mentioned extracted volatile oil, mixed evenly, and divided into net contents 9 g...

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Abstract

The invention relates to a Chinese medicinal sugar-free gynaecopathia treating particle for treating gynaecopathia and a preparation method thereof. The particle is prepared from the following raw and auxiliary materials in parts by weight: 115 parts of prepared rehmannia root, 46 parts of szechuan lovage rhizome, 93 parts of white paeony root, 46 parts of Chinese mugwort leaf, 69 parts of Chinese angelica, 46 parts of liquoric root, 69 parts of donkey-hide gelatin, and non-cane-sugar auxiliary materials consisting of 100-800 parts of a diluent, 0-100 parts of a wetting agent, 0-50 parts of a bonding agent and 0-10 parts of a flavoring agent. The preparation method comprises the following steps of: extracting volatile oil from Chinese angelica, Chinese mugwort leaf and szechuan lovage rhizome, adding water into decoction dregs, white paeony root, prepared rehmannia root and liquoric root for decocting twice for 3 hours in a first time and 2 hours in a second time, combining decoctions, standing for 18-24 hours, and filtering to obtain an extract; and smashing the donkey-hide gelatin, adding donkey-hide gelatin powder and non-cane-sugar auxiliary material powder into the extract, preparing into particles, drying and spraying volatile oil. The particle is a sugar-free preparation, and is suitable for people suffering from diabetes and other people with no sugar requirements; and the using amount of the auxiliary materials is lowered remarkably.

Description

technical field [0001] The invention belongs to the technical field of drugs for treating gynecological diseases, and in particular relates to a traditional Chinese medicine sugar-free Fukangbao granule for treating gynecological diseases and a preparation method thereof. Background technique [0002] At present, dysmenorrhea, vaginal bleeding caused by drug abortion, artificial abortion, and cesarean section in the middle and early stages of pregnancy are common diseases and frequently-occurring diseases of young and middle-aged women, which seriously plague modern women and endanger the physical and mental health of young and middle-aged women. Fenbid is often used to treat dysmenorrhea, and vitamin K4 plus antibiotics is often used to treat vaginal bleeding, but both have large side effects and the therapeutic effect is not obvious, so they should not be used routinely. Motherland medicine believes that women are based on blood. The physiological characteristics of women'...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/804A61K9/16A61P15/00A61K35/36
Inventor 高三东
Owner 武汉哈瑞医药有限公司
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