A pharmaceutical composition containing 18 kinds of amino acids

A composition and amino acid technology, applied in the field of medicine, can solve problems such as huge investment
CN102626409BInactive Publication Date: 2016-04-13郑飞雄
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
郑飞雄
Publication Date
2016-04-13
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses a pharmaceutical composition containing 18 amino acids. The pharmaceutical composition containing 18 amino acids is characterized in that raw materials of 18 amino acids and auxiliary materials of an antioxidant and a pH conditioning agent are prepared into compound amino acid injections (18AA-IV) having different concentrations, wherein the compound amino acid injection is the pharmaceutical composition containing 18 amino acids and has a pH value of 3.5 to 5.5. The pharmaceutical composition containing 18 amino acids does not contain a sulfite antioxidant and thoroughly prevents the damage of sulfites on the human body. Products of the pharmaceutical composition containing 18 amino acids are safer in clinical use. An accelerated stability test proves that the pharmaceutical composition (18AA-IV) containing 18 amino acids has the stability the same as or superior to the stability of commercial sulfite-containing like products.
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Description

technical field

[0001] The invention belongs to the technical field of medicine, and more specifically relates to a pharmaceutical composition containing 18 kinds of amino acids. Background technique

[0002] The pharmaceutical composition containing 18 kinds of amino acids is a sterilized aqueous solution prepared from 18 kinds of amino acids plus auxiliary materials, and is clinically used for parenteral nutrition.

[0003] Since amino acids are very unstable in solution, they are easily oxidized to produce a series of complex substances harmful to the human body. Since the compound amino acid injection was put into production and use in the 1960s, in order to ensure the stability of the product, sulfite substances with unique antioxidant capacity must be added, such as sodium bisulfite and sodium metabisulfite. Since people did not understand the harm of such substances to the human body at that time, manufacturers usually added them in large quantities without restricti...

Claims

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