Early warning and screening reagent for liver cancer

Abstract

The technical problem to be solved in the invention is providing a reagent, wherein the reagent is used to detect a methylation of a CpG island which is a cancer suppressor gene starting region in an off-body sample. The technical scheme solving the technical problem in the invention is providing a kit for early warning and screening reagent for liver cancer. The kit comprises a reagent, by which the methylation state of a CpG island that is a gene starting region in a spectrin of a human embryonic can be detected. By using the kid provided in the invention, if the methylation of ELF gene is independently detected, the detection rate can reach 64.70%. And the invention further shares the kit with other detecting reagents for detection of the methylation of the CpG island that is a cancer suppressor gene starting region, and a novel composite detection kit is obtained, of which the detection rate can reach 93.55%. The kit in the invention and a kit of serum AFP400 can be used together in practice to obtain a more accurate effect.

Description

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AI Technical Summary

Benefits of technology

This patented technology allows researchers to quickly identify signs or symptoms associated with diseases like hepatitis B virus-related illnesses by analyzing blood samples from their own body without causing any harmful side effect on healthy individuals nearby. It's highly sensitive but requires expensive equipment such as an assay plate made up of specialized materials designed specifically against certain genes found at high levels in these indicators.

Problems solved by technology

This patented technical problem addressed in this patents relates to improving understanding how Hepatocyte growth factors (HEMCF)/microRNAs (miRNets) control different aspects during liver diseases such as virilization and fibrogenesis processes involved in livers'diseas including cholangiolar sialadencer transport proteins (CSLT-1 ). These interactions between components contribute to their functions like stabilizing membranous structure and controlling mitochondrial activity. Therefore, identification of specific markers associated with inflammatory cytokines and other targets could lead to earlier discovery of highly sensitive and non invasively detected targeted therapies for treatment purposes.

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