Method for separating cholesteryl ester from lanolin

A technology of cholesteryl ester and lanolin, which is applied in the field of chemical engineering, can solve the problems of low cholesteryl ester content, inability to obtain cholesteryl ester, and high energy consumption, and achieve the effects of simple process, high selective separation ability, and low consumption
CN102731602BActive Publication Date: 2014-03-12ZHEJIANG UNIV

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
ZHEJIANG UNIV
Publication Date
2014-03-12

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Abstract

The invention discloses a method for separating cholesteryl ester from lanolin. The method comprises the following steps of: (1) taking lanolin as a raw material, and preparing a raw material liquid from the lanolin and a hydrophobic organic solvent; carrying out fractional extraction by taking one or more than two mixed solvents from moderate polar or polar organic solvents as extracting agents and a solvent which is the same as the raw material liquid solvent as a washing agent to obtain extraction liquid; and (2) carrying out vacuum concentration, washing with water and drying to obtain the cholesteryl ester. In the method, the organic solvents which are frequently-used in the industry are adopted, and the cholesteryl ester with a higher content can be efficiently separated from the lanolin, so the method has the advantages of high separation efficiency, less solvent consumption, high productivity, low cost, safety, environmental protection, easy industrial production, and the like.
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Description

technical field

[0001] The invention relates to a compound separation method, belongs to the technical field of chemical engineering, and in particular relates to a method for separating cholesteryl ester from lanolin. Background technique

[0002] Cholesterol is the first steroidal compound discovered, and it is one of the important components of animal organs, especially the brain and spinal cord tissue. It is also a raw material for the synthesis of bile acids, vitamin D and steroid hormones. Cholesteryl ester is a mixture of esters formed from cholesterol and a series of fatty acids with different carbon chain lengths. It has important applications in the fields of medicine, chemical industry, and cosmetics.

[0003] Lanolin is a substance secreted by the sheep's sebaceous glands and adhered to the wool coat. It is mainly an ester formed by fatty acids and almost equal amounts of fatty alcohols, sterols, and trimethyl sterols. It also contains a small amount of free acid...

Claims

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