Application of chymotrypsin preparation in treating oral ulcer

A technology for chymotrypsin and oral ulcers, applied in the field of medicine, can solve problems such as inability to exert curative effect for a long time, loss, and non-film-forming properties
CN102755641AInactive Publication Date: 2012-10-31SHANGHAI NATURE STANDARD R&D & BIOTECH +1
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
SHANGHAI NATURE STANDARD R&D & BIOTECH
Publication Date
2012-10-31
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention relates to an application of a chymotrypsin preparation in treating oral ulcer. According to the invention, the preparation comprises 0.1-30 parts by weight of chymotrypsin and 70-99.9 parts by weight of a solid excipient which is selected from carboxyvinyl polymer (Carbopol), hyaluronic acid, poly(aspartic acid), gum Arabic, citric acid, sodium alginate, acrylic resin, magnesium stearate, starch, or a combination thereof. The oral ulcer preparation is a solid or semi-solid preparation. In the preparation, the content of the raw material chymotrypsin is higher than 95.0%. The preparation can be powder or tablets. The invention also provides a preparation method of the preparation. The oral ulcer preparation provided by the invention is advantaged in simple application, good curative effect, and long action duration.
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Description

technical field

[0001] The invention relates to the application of chymotrypsin preparation in treating oral ulcer and belongs to the technical field of medicine. Background technique

[0002] Oral ulcers are common and frequently-occurring diseases in daily life, and are painful, solitary or recurrent ulcers of the oral mucosa caused by various reasons. The most notable feature of this disease is recurrent attacks. The number of ulcers ranges from few to many, and the sites are from front to back. They are mainly found in the oral mucosa, gums, upper and lower sides of the tongue and throat. The ulcer surface is as big as soybeans and as small as rice grains. There are white erosive rot membranes. In mild cases, the disease may occur once every few months. In severe cases, the interval will gradually shorten and even ulcers will come and go, and will not heal for several years or even decades.

[0003] The etiology and pathogenic mechanism of oral ulcer are still unclear. ...

Claims

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