Whole-body and only-nose compatible breathing toxicity test equipment

A toxicity test, compatible technology, applied in medical science, measuring devices, instruments, etc., can solve problems such as experimental errors, experimental animals cannot move freely, and occupy a large area

Active Publication Date: 2012-11-21
TIANJIN HOPE IND & TRADE
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  • Summary
  • Abstract
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  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] With the development of scientific research on people's respiratory diseases, more and more pathological studies require respiratory toxicity experiments to verify the degree of harmful effects of certain gaseous substances on humans. In the past, independent systemic respiratory toxicity test equipment or only The nasal respiratory toxicity test equipment is completed, and the whole body respiratory toxicity test equipment uses the whole body cabin to put experimental animals into the experiment. There are many drugs, imprecise, the skin of the animal will be infected, and the accuracy of the result will be affected by the poisoning of the animal through licking, etc., but only the nasal respiratory toxicity test equipment uses animal fixing frames to restrain the experimental animals and only expose the nose to align with their respective noses. The advantages of the gas distribution branch pipe are that it can control the gas to flow only to the nose of the experimental animal without polluting the skin of the experimental animal, and will not cause experimental interference caused by animal licking, and because the flow cavity is small, it can save experimental drugs and control at the s

Method used

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  • Whole-body and only-nose compatible breathing toxicity test equipment
  • Whole-body and only-nose compatible breathing toxicity test equipment

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Embodiment

[0023] When using a whole-body and nose-only respiratory toxicity test equipment of the present invention to carry out a two-way respiratory toxicity test with one device, the mixed gas to be tested should be prepared in advance and the flow rate of the exhaust valve should be adjusted to ensure the basic conditions of the test. , explained in two steps below:

[0024] 1. When selecting only the nasal breathing toxicity test method, follow the figure 1 : The experimental animal (7) to be tested should be put into the nose-only holder (22) with the tail top cover (8) opened, then the tail top cover (8) should be fixed, and the push bolt (9) should be adjusted to tighten the experiment. The buttocks of the animal (7) make the experimental animal (7) only expose the nose while the head and the head and neck sealing rubber ring (19) are tight and airtight, and the lifting motor (2) and the gear (1) are controlled to drive the lifting rack (28 ) so that the main airflow tube (5) m...

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Abstract

The invention provides whole-body and only-nose compatible breathing toxicity test equipment which comprises a main gas flow round tube, a lifting rack and experimental animals, wherein the main gas flow round tube and the lifting rack are arranged on a whole-body cabin and can move up and down; a plurality of branch pipes are arranged along the periphery of the main gas flow round tube; a plurality of branch pipes are respectively and oppositely inserted into rat rack mounting holes; only noses of the experimental animals are exposed out; mixed gas flow flows to the noses of the experimental animals through the corresponding branch pipes to be breathed, carbon dioxide gas which is breathed out overflows from rat rack side flow holes and flows downward to an exhaust port along a side flow cylinder to be exhausted so as to complete the only-nose breathing toxicity test; and when the whole-body breathing toxicity test is carried out, the main gas flow round tube is lifted up, single animal cages are arranged at the bottom of the whole-body cabin, the mixed gas flow is diffused downward in the side flow cylinder from the main gas flow round tube along the branch pipes to carry out whole-body breathe-in toxicity test. The whole-body and only-nose compatible breathing toxicity test equipment has the beneficial effects that one set of equipment has functions of the whole-body breathing toxicity test and the only-nose breathing toxicity test; and the whole-body and only-nose compatible breathing toxicity test equipment is widely applied in the scientific research on the occupational health, the military science, the environmental protection, the respiratory medicine and the like.

Description

technical field [0001] The present invention provides a whole body and nose-only respiratory toxicity test equipment. Background technique [0002] With the development of scientific research on people's respiratory diseases, more and more pathological studies require respiratory toxicity experiments to verify the degree of harmful effects of certain gaseous substances on humans. In the past, independent systemic respiratory toxicity test equipment or only The nasal respiratory toxicity test equipment is completed, and the whole body respiratory toxicity test equipment uses the whole body cabin to put experimental animals into the experiment. There are many drugs, imprecise, the skin of the animal will be infected, and the accuracy of the result will be affected by the poisoning of the animal through licking, etc., but only the nasal respiratory toxicity test equipment uses animal fixing frames to restrain the experimental animals and only expose the nose to align with their...

Claims

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Application Information

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IPC IPC(8): G01N33/00
CPCA61D7/04
Inventor 范维林张燊羡丽艳迟晓东韩卫庆
Owner TIANJIN HOPE IND & TRADE
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