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A compound traditional Chinese medicine for treating endometriosis and its preparation method and application

A technology of endometrium and compound traditional Chinese medicine, which is applied in the direction of medical preparations containing active ingredients, drug combinations, and pharmaceutical formulas, can solve problems such as recurrence, hypofunction of the pituitary-ovarian axis, and easy recurrence, and achieve the goal of inhibiting cell proliferation Effect

Active Publication Date: 2016-01-20
JIANGSU PROVINCE INST OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, surgical treatment is easy to cause adhesions leading to postoperative abdominal pain and infertility, and unresected lesions and uncorrected pathophysiological mechanisms can cause recurrence; GnRHa drugs can cause hypofunction of the pituitary-ovarian axis, causing similar menopausal syndrome and Prone to relapse shortly after drug discontinuation

Method used

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  • A compound traditional Chinese medicine for treating endometriosis and its preparation method and application
  • A compound traditional Chinese medicine for treating endometriosis and its preparation method and application
  • A compound traditional Chinese medicine for treating endometriosis and its preparation method and application

Examples

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Effect test

Embodiment 1

[0022] The above-mentioned compound Chinese medicine for treating endometriosis includes the following components in parts by weight: 10 parts of raw Puhuang, 10 parts of Wulingzhi, 2 parts of blood, 15 parts of raw Astragalus, 10 parts of Chuanduan, and 10 parts of medicine, 10 parts of Corydalis Corydalis, 10 parts of Toosendan.

[0023] The preparation method is to mix raw Puhuang, Wulingzhi, raw astragalus, Chuanduan, sunburned myrrh, Corydalis corydalis and Toosendan, add 16 times the weight of water and soak for 30 minutes, decoct twice, each time on high heat After decocting, decoct on low heat for 1.5 hours, filter out the medicinal liquid, combine the two filtered medicinal liquids, mix and concentrate, and directly add the concentrated medicinal liquid to the powdered dried blood in the prescribed amount.

Embodiment 2

[0025] The above-mentioned compound Chinese medicine for treating endometriosis includes the following components in parts by weight: 8 parts of raw Puhuang, 8 parts of Wulingzhi, 1 part of blood, 12 parts of raw Astragalus, 8 parts of Chuan Duan, sunburn 8 parts of medicine, 8 parts of Corydalis Corydalis, 8 parts of Toosendan.

[0026] The preparation method is to mix raw Puhuang, Wulingzhi, raw astragalus, Chuanduan, sunburned myrrh, Corydalis corydalis and Toosendan, add 15 times the weight of water and soak for 30 minutes, decoct twice, each time on high heat After decocting, decoct on low heat for 1 hour, filter out the medicinal liquid, combine the two filtered medicinal liquids, mix and concentrate, and directly add the concentrated medicinal liquid to the powdered dried blood in the prescribed amount.

Embodiment 3

[0028] The above-mentioned compound Chinese medicine for treating endometriosis includes the following components in parts by weight: 12 parts of raw Puhuang, 12 parts of Wulingzhi, 3 parts of blood, 20 parts of raw Astragalus, 12 parts of Chuanduan, and 12 parts of medicine, 12 parts of Corydalis Corydalis, 12 parts of Toosendan.

[0029] The preparation method is to mix raw Puhuang, Wulingzhi, raw astragalus, Chuanduan, sunburned myrrh, corydalis, and Toosendan, add 20 times the weight of water and soak for 30 minutes, decoct twice, each time on high heat After decocting, decoct on low heat for 2 hours, filter out the medicinal liquid, combine the two filtered medicinal liquids, mix and concentrate, and directly add the concentrated medicinal liquid to the powdered dried blood in the prescribed amount.

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PUM

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Abstract

The invention discloses compound traditional Chinese medicine for treating endometriosis. The compound traditional Chinese medicine comprises, by weight, 8-12 parts of Pollen Typhae, 8-12 parts of trogopterus dung, 1-3 parts of dragon's blood, 12-20 parts of astragali radix, 8-12 parts of dipsacus root, 8-12 parts of roasted myrrh, 8-12 parts of corydalis yanhusuo, and 8-12 parts of szechwan chinaberry fruit. The invention further discloses a preparation method and application of the compound traditional Chinese medicine. The compound traditional Chinese medicine brings the advantages of multi-targeted treating of traditional Chinese medicine into full play. Lab observation of development of ectopic endometrium in a drug inhibited rat endometriosis model shows that the compound traditional Chinese medicine can inhibit development of endometriosis in terms of inhibiting cell proliferation, angiogenesis and invasion in ectopic endometrium tissues, lowering inflammatory cell factor level in peritoneal fluid and the like.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a compound traditional Chinese medicine for treating endometriosis, a preparation method and application thereof. Background technique [0002] Endometriosis is a common gynecological disorder in which active endometrial tissue occurs outside the endometrial layer. Pathologically, endometriosis presents benign morphological manifestations, but has the ability to grow, invade and distantly metastasize similar to malignant tumors. Implantation and invasion of ectopic endometrium depend on adequate angiogenesis and blood supply. Changes in the intraperitoneal immune environment play an important role in the development of endometriosis. The interaction between cytokines and cells in peritoneal fluid provides a suitable environment for the implantation and invasion of ectopic endometrium. [0003] Laparoscopic surgery and gonadotropin-releasing ho...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/889A61K36/896A61P15/00
Inventor 万贵平张真真邢玉霞汤伟伟桂涛曹鹏胡春萍
Owner JIANGSU PROVINCE INST OF TRADITIONAL CHINESE MEDICINE