Application of Mucosolvan in preparing product for cleaning depleted uranium particles in lung

A depleted uranium product technology, applied in the direction of anti-virus, respiratory diseases, urinary system diseases, etc., can solve the problems of difficult discharge, radiation toxicity, human chemical toxicity, etc., and achieve the effect of reducing damage

Inactive Publication Date: 2013-06-12
INST OF RADIATION MEDICINE ACAD OF MILITARY MEDICAL SCI OF THE PLA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The aerosols produced by DU explosions will have potential impacts on the environment and human health, especially DU aerosols enter the lungs through inhalation, and are difficult to discharge after long-term retention, causing chemical toxicity and radiotoxicity to the human body

Method used

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  • Application of Mucosolvan in preparing product for cleaning depleted uranium particles in lung
  • Application of Mucosolvan in preparing product for cleaning depleted uranium particles in lung

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0019] Example, the clearance effect of Mucosultan on insoluble depleted uranium particles in the lung

[0020] Divide 90 male Wistar rats into 3 groups randomly, 30 in each group, and perform the following treatments:

[0021] MU group: On the first day of the experiment, the rats were short-acted anesthetized with ether, and then the endotracheal intubation was visualized with a poisoning device (patent No. ZL201020264213.2), and the DU particles were suspended after simulating airway inhalation pressure and pressurized air. Injection into the lungs (DU particle suspension is obtained by suspending DU particles in normal saline, each rat injects 200μl containing 500μg DU particles; then for 7 consecutive days (i.e. day 1 to day 7) Gave Mucosultan (25 mg Mucosultan is given to each rat every day);

[0022] DU group: On the first day of the experiment, the rats were short-acted anesthetized with ether, and then the tracheal intubation was visualized with the poisoning device (Patent...

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Abstract

The invention discloses an application of Mucosolvan in preparing a product for cleaning depleted uranium particles in lung. According to the invention, a new application of Mucosolvan is discovered, namely an application of Mucosolvan in preparing a product for cleaning depleted uranium particles in lung; a product for cleaning depleted uranium particles in lung is protected, and the active ingredient of the product is Mucosolvan; and Mucosolvan can obviously clean depleted uranium particles in lung so as to reduce damage of the lung tissue and kidney tissue caused by the depleted uranium particles and provide a basis to the prevention of the lung absorbing insoluble DU (depleted uranium) particles.

Description

Technical field [0001] The invention relates to the application of Mucosultan in the preparation of products for clearing out depleted uranium particles in the lungs. Background technique [0002] Depleted uranium (DU) is natural uranium 235 The remaining by-products after U enrichment are extremely easy to burn. DU has good machining performance, excellent combat performance and low cost, making it an ideal military material. In the Gulf War, the United States and its allies used weapons made with DU as raw materials for the first time on a large scale, showing excellent military effectiveness when attacking hard targets such as Iraqi tanks and armor. [0003] The aerosol produced by the DU explosion will have potential impacts on the environment and human health, especially the DU aerosol enters the lungs through respiration and is difficult to be discharged for a long time, causing chemical and radiotoxicity to the human body. The key to promoting the excretion of insoluble ra...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/137A61P11/00A61P13/12A61P39/02
Inventor 朱茂祥潘秀颉杨陟华刘坤璐徐龙
Owner INST OF RADIATION MEDICINE ACAD OF MILITARY MEDICAL SCI OF THE PLA
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