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Skin wound repairing pharmaceutical composition

A skin wound and drug technology, applied in the field of medicine, to achieve the effects of strong antibacterial properties, promoting regeneration, and inhibiting the reproduction of pathogens

Inactive Publication Date: 2014-07-09
南通海门凤成旅游文化发展有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] In order to overcome the technical defects of lack of effective therapeutic drugs and poor therapeutic effect in the existing skin wound repair process, the present invention provides a new pharmaceutical composition for skin wound repair, which can solve the problems of skin wounds, incisions and ulcerated wounds. Treatment problem, therefore pharmaceutical composition of the present invention has very broad medical application prospect

Method used

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  • Skin wound repairing pharmaceutical composition

Examples

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Comparison scheme
Effect test

Embodiment 1

[0030] Embodiment 1: skin wound repair gel of the present invention

[0031] Ingredients include chitosan, sodium hyaluronate, polycresol, asiaticoside. The gel comprises: 3% chitosan, 0.3% sodium hyaluronate, 0.3% polycresol and 0.01% asiaticoside in parts by weight.

[0032] Take the preparation of 1000 g of gel as an example, which contains 30 g of chitosan, 3 g of sodium hyaluronate, 3 g of polycresol, and 0.1 mg of asiaticoside. The specific preparation method is to add 30g of chitosan (water-soluble) and 3g of sodium hyaluronate into 960ml of purified water, and use a high-speed disperser to fully dissolve it; at the same time, fully disperse 3g of polycresol sulfaldehyde in 5ml of propylene glycol, Add the dispersed polycresol sulfonal into the solution of the above-mentioned fully dissolved chitosan and sodium hyaluronate, continue stirring to mix the components evenly, adjust the pH value of the solution between 5.0 and 6.0, and the product becomes Gel-like; f...

Embodiment 2

[0033] Embodiment 2: Gel for skin wound repair of the present invention

[0034] A gel for repairing skin wounds, comprising: 5% chitosan, 0.1% sodium hyaluronate, 0.1% polycresol, 0.5% asiaticoside .

[0035] Taking the preparation of one kilogram of gel as an example, each kilogram of gel contains 50g of chitosan, 1g of sodium hyaluronate, 1g of polycresol, and 5mg of asiaticoside. The specific preparation method is to add 50g of chitosan (water-soluble) and 1g of sodium hyaluronate into 960ml of purified water, and use a high-speed disperser to fully dissolve it; at the same time, fully disperse 1g of polycresol sulfaldehyde in 5ml of propylene glycol Add the dispersed polycresol sulfonal into the solution of the above-mentioned fully dissolved chitosan and sodium hyaluronate, continue stirring to mix the components evenly, adjust the pH value of the solution between 5.0 and 6.0, and the product becomes Gel-like; finally use a 0.22um microporous membrane to aseptica...

Embodiment 3

[0036] Embodiment 3: Gel for skin wound repair of the present invention

[0037] A gel for repairing skin wounds, comprising: 4% chitosan, 0.1% sodium hyaluronate, 0.2% polycresol, 0.04% asiaticoside .

[0038] Taking the preparation of one kilogram of gel as an example, each kilogram of gel contains 40g of chitosan, 1g of sodium hyaluronate, 2g of polycresol, and 0.4mg of asiaticoside. The specific preparation method is to add 40g of chitosan (water-soluble) and 1g of sodium hyaluronate into 960ml of purified water, and use a high-speed disperser to fully dissolve it; at the same time, fully disperse 2g of polycresol sulfonal in 5ml of propylene glycol, Then add the dispersed polycresol sulfonal into the above-mentioned fully dissolved chitosan and sodium hyaluronate solution, continue stirring to mix the components evenly, adjust the pH value of the solution between 5.0 and 6.0, and the product becomes Gel-like; finally use a 0.22um microporous membrane to aseptically fi...

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Abstract

The invention discloses a medicinal composition for repairing skin wounds, which belongs to the field of medicine. The pharmaceutical composition of the present invention contains polycresol and asiaticoside, wherein the ratio of parts by weight of polycresol and asiaticoside in the pharmaceutical composition is preferably (0.1-0.6) : (0.01-0.5). In the present invention, the above-mentioned pharmaceutical composition is further prepared into external preparations such as gel, liniment, ointment or ointment for the treatment of skin wound repair. The pharmaceutical composition of the present invention can accelerate the repair and regeneration of wound tissue, promote healing and It can reduce scar formation, so it has a very broad medical application prospect.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a medicinal composition for repairing skin wounds. Background technique [0002] Superficial abrasion of the skin surface is a common type of trauma in the clinical work of plastic surgery, especially in exposed parts of the body such as the face and face; it has a large trauma area, is prone to infection, has poor surgical efficacy, and has a long course of conventional dressing changes. Not sure enough; after healing, the lesions tend to form scars, pigment changes and other sequelae, which cause great harm to the patient's body and mind. Wound healing is one of the hot issues in current clinical research. Skin wound repair is a complex biological process, including pathophysiological processes such as inflammatory response, cell proliferation, collagen metabolism, hair follicle formation, and pigmentation deposition. In the past, it was generally believed that wound healing ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/795A61K36/23A61K47/36A61P17/02
Inventor 刘学键
Owner 南通海门凤成旅游文化发展有限公司
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