Novel method for detecting and evaluating blood coagulation function

A technology of function detection and evaluation method, which is applied in the field of medical clinical examination, and can solve the problems that the test results are greatly affected by the blood collection time, the detection speed is slow, and the manufacturing difficulty of the instrument is large.

Inactive Publication Date: 2013-08-14
江苏英诺华医疗电子科技有限公司
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Problems solved by technology

This method has disadvantages such as difficulty in manufacturing the instrument, greater influence of th

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  • Novel method for detecting and evaluating blood coagulation function
  • Novel method for detecting and evaluating blood coagulation function
  • Novel method for detecting and evaluating blood coagulation function

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Embodiment Construction

[0005] Prepare the blood sample to be tested, mix it evenly in a special sample cup, and obtain the count value of platelets and red blood cells in the original blood sample by sampling and testing by the detection system. The counting detection method can be carried out by electrical impedance method or by optical scattering method and the like. Then add a blood coagulation-inducing reagent to the blood sample, and continue to mix the blood sample evenly after the reagent is added to the blood sample, so that the reagent can fully contact and react with the blood sample. Then count and detect the number of platelets and red blood cells in the blood sample again. Finally, the change ratio of the platelets and red blood cells obtained by the detection and the changes in the number of platelets and red blood cells before adding the blood coagulation-inducing reagent can be calculated respectively, and the change rate of the two main blood cell particles in the blood sample coagu...

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Abstract

The invention disclose a method for detecting and evaluating blood coagulation function by directly detecting change of erythrocyte and platelet quantity by whole blood after and before a reagent for inducting blood to coagulate is added. The method not only can comprehensively reflect a total blood coagulation function level of a blood sample, but also can respectively directly reflect participation of platelet and erythrocyte in a blood coagulation process and the coagulation function of various blood cells, and can comprehensively reflect blood solidification capability. The method, combining different blood coagulation reagent, by change of the platelet and erythrocyte quantity, reflect a blood coagulation path function in the blood sample, and the function of various blood coagulation factors in the blood.

Description

1. Technical field [0001] The invention relates to a blood coagulation function detection and evaluation method for detecting and judging blood coagulation ability by detecting changes in the number of red blood cells and platelets in blood. It belongs to the field of medical clinical examination. 2. Background technology [0002] At present, the detection of blood coagulation function is mainly divided into the detection of coagulation function using plasma (such as detection of PT, APTT, TT, FIB, etc.). Circumstances are somewhat different and therefore have certain limitations. At present, the method of using whole blood to detect coagulation function is mainly thromboelastography or thrombelastograph (Thrombelastograph). In the blood sample of the detection cup, the rotation of the detection cup is different with the formation and strength of the thrombus during detection, and the deviation of the detection needle is different, and the formation and strength (elasticit...

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Application Information

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IPC IPC(8): G01N33/49
Inventor 徐新
Owner 江苏英诺华医疗电子科技有限公司
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