Production method of squalene

A technology for squalene and squalene synthase, applied in the field of genetic engineering, can solve the problems of high price of squalene, high unit cost, etc., and achieves a technology that is conducive to large-scale application, simple production method, and increased output. Effect
CN103266137BActive Publication Date: 2014-09-17QINGDAO VLAND BIOTECH GRP
3 Cites 7 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
QINGDAO VLAND BIOTECH GRP
Publication Date
2014-09-17

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

The invention relates to a production method of squalene, and in particular relates to a method for cloning a squalene synthetase gene and co-expressing in escherichia coli so as to establish a recombinant strain capable of synthesizing squalene. The production method of squalene, provided by the invention, is simple and efficient, the established escherichia coli engineering bacteria can be used for producing squalene with a high yield and can be widely applied to the fermentation production of squalene, the output of squalene is increased, and then the large-scale application of squalene is facilitated.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The invention belongs to the technical field of genetic engineering, and in particular relates to a squalene production method, namely a squalene biosynthesis method, and a constructed recombinant bacterial strain. technical background

[0002] Squalene is a lipid unsaponifiable substance, originally discovered from shark liver oil, named Sqμalene in 1914, and its chemical name is 2,6,10,15,19,23-hexamethyl-2 ,6,10,14,18,22-Tetracosahexaene, an open-chain triterpene, also known as cod liver oil terpene, can improve the activity of superoxide dismutase (SOD) in the body, enhance the body's immunity, and improve sexual function , anti-aging, anti-fatigue, anti-tumor and other physiological functions, it is a non-toxic marine bioactive substance with the effect of preventing and curing diseases.

[0003] As the main source of squalene, deep-sea shark cod liver oil needs to be obtained by hunting a large number of deep-sea sharks, which leads to a series ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More