Traditional Chinese medicine composition

A technology of composition and natural medicine, which is applied in the direction of drug combination, antineoplastic drug, pharmaceutical formula, etc., to achieve the effects of good side effects, obvious synergistic effect, and enhanced inhibitory effect

Inactive Publication Date: 2013-09-04
阚兆云
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  • Abstract
  • Description
  • Claims
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Problems solved by technology

[0003]Chemotherapy-associated diarrhea, in terms of its clinical manifestations, belongs to the category of "diarrhea" in traditional Chinese medicine. The research on diarrhea in traditional Chinese medicine is remarkable, but at present There is no Chinese patent medicine that can relieve diarrhea and increase efficacy against cancer chemotherapy

Method used

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  • Traditional Chinese medicine composition
  • Traditional Chinese medicine composition

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Embodiment approach

[0030] The first step: preparation of various extracts

[0031] (1) Preparation of Coptis chebula decoction concentrated extract

[0032] According to the compatibility ratio of 1:1 or 1-4:1, take Coptidis and Myrobalan, soak in 10 times the amount of distilled water for 1 hour, heat and decoct on an electric stove with asbestos net for 1 hour, filter with silk cloth, save the filtrate, and recycle the dregs. Add 6 times of distilled water, soak, decoct, and filter in the same way, mix the two filtrates, heat and concentrate to a small volume, filter with an ultrafiltration membrane, and dry under reduced pressure at 70°C for 36 hours in a vacuum drying oven to obtain a brown-yellow powder.

[0033] (2) preparation of berberine

[0034] Coptis rhizome is crushed, add ethanol, heat and reflux in water bath for 0.5h, suction filter, repeat the above operation twice for the filter residue, combine the filtrate, recover ethanol under reduced pressure, then add 1% acetic acid to h...

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Abstract

The invention relates to a natural pharmaceutical composition and its preparation method and use in preparation of drugs for reducing toxicity and improving effects in cancer chemotherapy. The natural pharmaceutical composition is a traditional Chinese medicine composition and is composed of coptis-medicine terminalia fruit water-decoction condensation extract, berberine and 70% ethanol extract of medicine terminalia fruit according to a ratio of (2-9): (3-8): (1-3). The natural pharmaceutical composition has excellent effects of treating cancer chemotherapy-related diarrhoea and can improve cancer chemotherapy effects.

Description

technical field [0001] The present invention relates to a kind of natural medicine composition, more specifically relate to a kind of natural medicine composition which is composed of Coptis chebula decoction concentrated extract, berberine and chebula 70% ethanol extract, the preparation of the natural medicine composition The method and the use of the natural medicine composition in preparing medicines for reducing cancer chemotherapy-related diarrhea and synergizing cancer treatment. Background technique [0002] Malignant tumor is one of the main diseases that endanger human survival and health at present. Its treatment methods include surgery, chemotherapy, radiotherapy, and traditional Chinese medicine treatment, and the effect of chemotherapy on tumors is particularly prominent. Chemotherapy drugs used alone or in combination can cause toxic and side effects such as diarrhea in patients. Diarrhea after tumor chemotherapy is also called chemotherapy-associated diarrhea...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/718A61P1/12A61P35/00A61K36/185A61K31/4375
Inventor 阚兆云
Owner 阚兆云
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