Artificial bone material and preparation method thereof

A technology of artificial bone and raw materials, applied in the field of materials, can solve problems such as low porosity, poor pore traffic performance, and insufficient mechanical strength, and achieve the effects of low printing temperature, good formability, and low melting point
CN103285427BActive Publication Date: 2014-11-05珠海市红旌发展有限公司
8 Cites 1 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
珠海市红旌发展有限公司
Publication Date
2014-11-05

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
Patent Text Reader

Abstract

The invention discloses a preparation method of an artificial bone material. The preparation method comprises providing raw materials including hydroxyapatite, collagen and nano-crystalline cellulose. The preparation method comprises: step (S1100). dropping a solution containing PO4<3-> of 0.05-0.5 mol / L into a collagen solution with a mass percent concentration of 0.1-1%, stirring to keep in reserve; step (S1200). preparing a nano-crystalline cellulose solution with a mass percent concentration of 0.5-10%, and mixing the nano-crystalline cellulose solution and the collagen PO4<3-> solution prepared by the step (S1100), stirring and homogenizing; step (S1300). adding a solution containing Ca<2+> of 0.2-0.8 mol / L into the collgen / nano-crystalline cellulose composite solution prepared by the step (S1200), setting the mol ratio of Ca to P as 1.67, adjusting the pH to 7-9 with an alkaline solution and precipitating, freeze-drying the precipitation to obtain the artificial bone material.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The invention relates to a material, in particular to an artificial bone material and a preparation method thereof. Background technique

[0002] Bone tissue is composed of organic components and inorganic components. In adult bone, the organic components account for about 1 / 3, and the inorganic components account for about 2 / 3. Collagen accounts for about 95% of the organic components, while the inorganic components are mainly hydroxyapatite. Therefore, it can be said that natural bone is composed of low crystallinity hydroxyapatite and collagen.

[0003] Synthetic hydroxyapatite has good biocompatibility and bioactivity, it is an excellent hard tissue replacement material, and because the grains of hydroxyapatite have surface effect and volume effect, after implanted in the human body It can bond with human tissue through hydrogen bonds to achieve perfect affinity, has no immune rejection phenomenon and has certain bone conduction properties. It ha...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More