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Compound disinfectant, and preparation method and applications thereof

A technology of disinfectant and application, which is applied in the field of compound disinfectant and its preparation, to achieve the effect of alleviating olfactory stress and enhancing antibacterial activity

Active Publication Date: 2013-10-02
SICHUAN HENGTONG ANIMAL PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] There is no report on the combined use of povidone-iodine and natural antibacterial drugs

Method used

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  • Compound disinfectant, and preparation method and applications thereof
  • Compound disinfectant, and preparation method and applications thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0026] The preparation of embodiment 1 compound disinfectant of the present invention

[0027] Compound disinfectant of the present invention is made up of povidone-iodine, tea tree oil, polysorbate 80, potassium iodate, and its percentage by weight is as follows: povidone-iodine 10%, tea tree oil 0.1%, Tween 802%, potassium iodate 0.3% , and the balance is water.

[0028] The preparation method of povidone-iodine and tea tree oil compound disinfectant solution: mix tea tree oil and Tween 80 evenly, add appropriate amount of water to form a clear solution. Dissolve povidone-iodine in an appropriate amount of water, add potassium iodate and mix well. Then mix the tea tree oil solution and the povidone-iodine solution evenly, and get final product at constant volume.

[0029] Among them, Tween 80 is used as a solubilizer of tea tree oil to make it easily soluble in water, thereby realizing uniform mixing with povidone-iodine solution. The solubilizer is not limited to Tween 80...

Embodiment 2

[0030] The preparation of embodiment 2 compound disinfectant of the present invention

[0031] Compound disinfectant of the present invention is made up of povidone-iodine, tea tree oil, polysorbate 80, potassium iodate, and its percentage by weight is as follows: povidone-iodine 8%, tea tree oil 0.12%, Tween 803%, potassium iodate 0.4% , and the balance is water. The preparation method refers to Example 1.

Embodiment 3

[0032] The preparation of embodiment 3 compound disinfectant of the present invention

[0033] Compound disinfectant of the present invention is made up of povidone-iodine, tea tree oil, Tween 80, potassium iodate, and its percentage by weight is as follows: povidone-iodine 12%, tea tree oil 0.08%, Tween 801%, potassium iodate 0.2% , and the balance is water. The preparation method refers to Example 1.

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Abstract

The invention discloses applications of povidone-iodine and tea tree oil in preparation of an external combined antibacterial agent. The combined antibacterial agent comprises, by weight, 0.000125 to 12 portions of povidone-iodine and 0.015625 to 2 portions of tea tree oil. The invention also provides a compound disinfectant containing povidone-iodine and tea tree oil, and a preparation method thereof. The combination of povidone-iodine and tea tree oil possesses synergistic interaction, and is capable of increasing the antimicrobial activities of both povidone-iodine and tea tree oil. In addition, tea tree oil is gentle and fragrant, so that olfactory stimulation caused by povidone-iodine is reduced.

Description

technical field [0001] The invention relates to a compound disinfectant and its preparation method and application. Background technique [0002] Povidone-iodine (PVP-I) is a prodrug preparation, an amorphous compound formed by combining polyvinylpyrrolidone and iodine, containing 9% to 12% of available iodine, and is a new type of water-soluble iodine. Compared with tincture of iodine (iodine solution), it has the characteristics of stable properties, good water solubility, non-irritating and volatile, mild and long-lasting effect, safe use, and easy elution of chromatography. It is a high-efficiency, broad-spectrum , low toxicity disinfectant. Its antibacterial mechanism is due to the surface activity and emulsification of PVP-I. On the one hand, the penetration of PVP-I is enhanced; inside, and the leakage of cell contents leads to the death of microorganisms. The results of multiple experimental studies show that: PVP-I can kill common gram-positive cocci, enterobacte...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01N65/08A01N59/12A01P1/00
Inventor 郭亮
Owner SICHUAN HENGTONG ANIMAL PHARMA
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