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Compound disinfectant, and preparation method and applications thereof

A use, povidone-iodine technology, applied in the field of compound disinfectant and its preparation, to achieve the effect of reducing olfactory stress and enhancing antibacterial activity

Active Publication Date: 2015-07-15
SICHUAN HENGTONG ANIMAL PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] There is no report on the combined use of povidone-iodine and natural antibacterial drugs

Method used

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  • Compound disinfectant, and preparation method and applications thereof
  • Compound disinfectant, and preparation method and applications thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] The preparation of embodiment 1 compound disinfectant of the present invention

[0027] Compound disinfectant of the present invention is made up of povidone-iodine, tea tree oil, polysorbate 80, potassium iodate, and its percentage by weight is as follows: povidone-iodine 10%, tea tree oil 0.1%, Tween 802%, potassium iodate 0.3% , and the balance is water.

[0028] The preparation method of povidone-iodine and tea tree oil compound disinfectant solution: mix tea tree oil and Tween 80 evenly, add appropriate amount of water to form a clear solution. Dissolve povidone-iodine in an appropriate amount of water, add potassium iodate and mix well. Then mix the tea tree oil solution and the povidone-iodine solution evenly, and get final product at constant volume.

[0029] Among them, Tween 80 is used as a solubilizer of tea tree oil to make it easily soluble in water, thereby realizing uniform mixing with povidone-iodine solution. The solubilizer is not limited to Tween 80...

Embodiment 2

[0030] The preparation of embodiment 2 compound disinfectant of the present invention

[0031] Compound disinfectant of the present invention is made up of povidone-iodine, tea tree oil, polysorbate 80, potassium iodate, and its percentage by weight is as follows: povidone-iodine 8%, tea tree oil 0.12%, Tween 803%, potassium iodate 0.4% , and the balance is water. The preparation method refers to Example 1.

Embodiment 3

[0032] The preparation of embodiment 3 compound disinfectant of the present invention

[0033] Compound disinfectant of the present invention is made up of povidone-iodine, tea tree oil, Tween 80, potassium iodate, and its percentage by weight is as follows: povidone-iodine 12%, tea tree oil 0.08%, Tween 801%, potassium iodate 0.2% , and the balance is water. The preparation method refers to Example 1.

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Abstract

The invention discloses applications of povidone-iodine and tea tree oil in preparation of an external combined antibacterial agent. The combined antibacterial agent comprises, by weight, 0.000125 to 12 portions of povidone-iodine and 0.015625 to 2 portions of tea tree oil. The invention also provides a compound disinfectant containing povidone-iodine and tea tree oil, and a preparation method thereof. The combination of povidone-iodine and tea tree oil possesses synergistic interaction, and is capable of increasing the antimicrobial activities of both povidone-iodine and tea tree oil. In addition, tea tree oil is gentle and fragrant, so that olfactory stimulation caused by povidone-iodine is reduced.

Description

technical field [0001] The invention relates to a compound disinfectant and its preparation method and application. Background technique [0002] Povidone-iodine (PVP-I) is a prodrug preparation, an amorphous compound formed by combining polyvinylpyrrolidone and iodine, containing 9% to 12% of available iodine, and is a new type of water-soluble iodine. Compared with tincture of iodine (iodine solution), it has the characteristics of stable properties, good water solubility, non-irritating and volatile, mild and long-lasting effect, safe use, and easy elution of chromatography. It is a high-efficiency, broad-spectrum , low toxicity disinfectant. Its antibacterial mechanism is due to the surface activity and emulsification of PVP-I. On the one hand, the penetration of PVP-I is enhanced; inside, and the leakage of cell contents leads to the death of microorganisms. The results of multiple experimental studies show that: PVP-I can kill common gram-positive cocci, enterobacte...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A01N65/08A01N59/12A01P1/00
Inventor 郭亮
Owner SICHUAN HENGTONG ANIMAL PHARMA
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