Chitosan sponge surgical dressing and preparation method thereof
A technology of chitosan and carboxymethyl chitosan, applied in medical science, bandages, absorbent pads, etc., can solve problems such as poor adsorption capacity, easy to become hard and brittle, unstable, etc., to achieve improved liquid absorption capacity, The effect of long-lasting adsorption capacity and excellent softness
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Embodiment 1
[0047] Embodiment one: a kind of chitosan sponge body medical dressing, specifically medical sponge, it comprises the component of following mass percentage: 2% carboxymethyl chitosan, 1% poloxamer, 2% poly ethylene glycol. The preparation method is as follows: add the poloxamer to purified water and soak for 1 hour; then use a stainless steel stirrer to stir the soaked poloxamer twice at a low speed of 100 r / min, and then reduce the speed to 100 r / min. Stir twice at a low speed of 180 r / min; after the poloxamer is completely dissolved, add polyethylene glycol to the solution, stir three times at a medium speed of 300 r / min until the solution is uniform, and then add to the solution while stirring Carboxymethyl chitosan is dissolved evenly to prepare foaming liquid, and then the stainless steel stirrer is stirred at a high speed of 700r / min. When the volume of the foaming liquid expands to 4-5 times of the original, the foaming liquid is injected into the silica gel In the mo...
Embodiment 2
[0048] Embodiment two: a kind of chitosan sponge body medical dressing, specifically medical sponge, it comprises the component of following mass percent: 7% carboxymethyl chitosan, 2% poloxamer, 5% poly ethylene glycol. The preparation method is as follows: add the poloxamer to purified water and soak for 3 hours; then stir the soaked poloxamer at a speed of 150 r / min with a stainless steel stirrer; wait until the poloxamer is completely dissolved Afterwards, polyethylene glycol was added to the solution , Stir at a speed of 400 r / min until the solution is uniform, then add carboxymethyl chitosan to the solution while stirring until it dissolves evenly to obtain a foaming liquid, then stir at a speed of 700 r / min, and wait for foaming When the volume of the liquid expands to 4-5 times of the original, pour the foaming liquid into the silicone mold tray, put it into the quick-freezing box as soon as possible, and let it be pre-frozen for 5 hours; Put it into a vacuum freeze ...
Embodiment 3
[0049] Embodiment three: a chitosan sponge medical dressing, specifically a medical sponge, which includes the following components by mass percentage: 3.5% carboxymethyl chitosan, 1% poloxamer, 2.5% poly ethylene glycol. The preparation method is as follows: add the poloxamer to purified water and soak for 3 hours; then use a stainless steel stirrer to stir the soaked poloxamer at a speed of 180 r / min; wait until the poloxamer is completely dissolved Afterwards, polyethylene glycol was added to the solution , Stir at a speed of 300 r / min until the solution is uniform, then add carboxymethyl chitosan to the solution while stirring until it dissolves evenly to obtain a foaming liquid, then stir at a speed of 600 r / min, and wait for foaming When the volume of the liquid expands to 4-5 times of the original, pour the foaming liquid into the silicone mold tray, put it into the quick-freezing box as soon as possible, and make it pre-freeze for 15 hours; Put it into the vacuum fre...
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