The application discloses a kind of high expansion
cellulose sponge with arch layer structure and its preparation method and application.The method is: with
carboxymethyl cellulose and
cellulose or its micro-nano
fiber as
raw material, crosslinking agent is added to prepare hydrogel.Subsequently, the
sponge sample is obtained by two-way freezing of hydrogel-
freeze drying, the
sponge sample is soaked in the solution that can be reacted with carboxyl, the solution includes at least one of
calcium chloride solution,
chitosan solution or the
mixed solution of two, finally, the sponge is obtained by secondary freeze-
drying.The sponge of the application has good
biocompatibility, high liquid
absorption rate, and the
volume expansion ratio can reach 10-15 times;after compression, it is used for bleeding site, can swell rapidly, block wound, and quickly stop bleeding.The sponge of the application has arch layer structure between
layers, can realize high compression, and can provide expansion support force for more than 4 hours.The sponge prepared by the application can be used for deep bleeding, such as deep and narrow penetrating wound bleeding, human interface bleeding, etc.