559 results about "Anti adhesive" patented technology

Tissue adhesives formed by reacting poly(hydroxylic) compounds derivatized with acetoacetate groups and / or polyamino compounds derivatized with acetoacetamide groups with an amino-functional crosslinking compound are disclosed. The use of the tissue adhesives for medical and veterinary applications such as topical wound closure; and surgical procedures, such as intestinal anastomosis, vascular anastomosis, tissue repair, and ophthalmic procedures; drug delivery; and anti-adhesive applications are described.

The present invention provides a biocompatible polymer composition for use in biomedical applications comprising a base molecule, a linker molecule and at least one initiator compound, said base molecule having at least two differing functionalities, and said linker molecule having a functionality reactive with at least one functionality of said base molecule, the first of said at least two functionalities of said base molecule enabling a first curing stage of said polymer composition by reaction with said linker molecule, and the second and any further functionality of said base molecule enabling second and further curing stages of said polymer composition, said first, second and any further curing stages being capable of activation simultaneously or independently of each other as required. The invention further provides uses of the polymer compositions of the invention in biomedical applications such as tissue engineering, dry delivery, as a bioadhesive in wound healing, as bone substitutes or scaffolds, as cements in dental and periodontal applications and as anti-adhesives or protective barriers.

A surface providing reduced adhesion to formed elements, having an element dimension such as formed element diameter, has a plurality of topographic features. The topographic features have a feature dimension less than the dimension of the formed element so as to reduce the accessible area of the surface available to the formed element for adhesion to the surface. The topographic features may include protrusions, such as pillars.

A stand-alone film is derived at least in part from fatty acids. The stand-alone film can have anti-adhesive, anti-inflammatory, non-inflammatory, and wound healing properties, and can additionally include one or more therapeutic agents incorporated therein. Corresponding methods of making the stand-alone film include molding, casting, or otherwise applying a liquid or gel to a substrate, and curing or otherwise treating to form the stand-alone film. The resulting stand-alone film is bioabsorbable.

A bio-absorbable stand-alone film is derived at least in part from fatty acids. The bio-absorbable stand-alone film can have anti-adhesive, anti-inflammatory, non-inflammatory, and wound healing properties, and can additionally include one or more therapeutic agents incorporated therein. The stand-alone film has one or more perforations or depressions formed therein. Corresponding methods of making the bio-absorbable stand-alone film with one or more perforations or depressions include molding, cutting, carving, puncturing or otherwise suitable methods to create the perforations or depressions in the bio-absorbable stand-alone film. The resulting stand-alone film is bioabsorbable.

A bio-absorbable stand-alone film is derived at least in part from fatty acids. The bio-absorbable stand-alone film can have anti-adhesive, anti-inflammatory, non-inflammatory, and wound healing properties, and can additionally include one or more therapeutic agents incorporated therein. The stand-alone film has one or more perforations or depressions formed therein. Corresponding methods of making the bio-absorbable stand-alone film with one or more perforations or depressions include molding, cutting, carving, puncturing or otherwise suitable methods to create the perforations or depressions in the bio-absorbable stand-alone film. The resulting stand-alone film is bioabsorbable.

Techniques for treating visceral or parietal membrane and tissue defects include the application of a collagen biomatrix to the defect to repair and regenerate a visceral or parietal membrane, for example in patients suffering tissue defects or undergoing visceral or parietal surgical treatment. Such approaches avoid persistent tissue leaks and their consequences such as fluid leaks and air leaks. The use of collagen biomatrix, optionally in conjunction with a fibrin sealant, an anti-adhesive, or both, can minimize tissue leaks or fluid leaks in injured patients suffering tissue defects or subjects undergoing surgery such as visceral or parietal resections and other operations.

A thermoplastic elastomer (“TPE”) which is oxygen-permeable is provided with excellent barrier properties against oxygen by melt-blending with a liquid polyisobutene oil plasticizer in an amount insufficient to render the plasticized elastomer tacky. If made tacky, enough detackifier is used to allow the product to be formed into a removable seal. The TPE may be a conventional thermoplastic vulcanizate or a block copolymer of a vinylaromatic compound, typically styrene, and a conjugated diene, typically butadiene or isoprene, or mixtures thereof; the block may be a diblock, triblock or higher block, but the preferred polyblock copolymer is a triblock with styrene end-blocks and a butadiene / isoprene mid-block. Preferably the diene mid-block is hydrogenated to provide a poly(lower)monoolefin mid-block. When the TPE is a TPV, some or all of the mineral oil used to make the TPV processable may also be substituted with the polyisobutene plasticizer. The elastomeric product is particularly useful for sealing elements for containers in which foods, beverages and medical products must be preserved for a long period.

A substrate having an anti-adhesive coating thereon. The coating is made from a coating composition comprising solid particles of a release agent different from boron nitride and a binder comprising surface-modified nanoscale solid particles.

The invention discloses a color drought-resistance water-retention sustained-release compound fertilizer and a method for producing the same, wherein the method comprises the followings steps of: measuring, crushing and uniformly mixing fertilizer raw materials, granulating by adopting an ammonia-acid method rotary drum granulating process, performing one-stage drying, semi-cooling and screening of grains, and sending the mixture to a coating machine; adopting a continuous melting rotary drum film-coating method coating process to perform compressed air atomization and uniform coating of color coating oil sprayed by a special nozzle; and adding a water-retaining agent and an anti-adhesive agent by a screw conveyor, and performing full stirring, cooling and packaging to obtain the finishedproducts. The color drought-resistance water-retention sustained-release compound fertilizer has the effects of drought resistance, water retention, nutrient preservation, soil condition improvement and environmental protection, and the appearance of the fertilizer has color marks; and when the fertilizer is applied to crops, the fertilizer has the advantages of increasing yield and incoming, along with simple production method, convenient operation, low cost and high benefits.

The invention provides an artificial dura mater with bioactivity, which is formed from a nano-bionic scaffold and hydrosol attached on the nano-bionic scaffold, wherein cell factors and / or a medicament are / is coated in the hydrosol; the nano-bionic scaffold at least contains two layers of connected structures, wherein the structure layer facing to the brain is a hydrophobic anti-adhesive electrospinning layer, and the structure layer opposite to the brain is a hydrophilic nano-cytoskeleton layer. The invention also provides a preparation method of the artificial dura mater, which comprises the following steps: preparing an electrospinning solution, a hydrosol solution containing the cell factors and / or the medicament and a cross linker solution; preparing the artificial dura mater through electrostatic spinning and biological printing. By simultaneously utilizing a biological printing technology and an electrostatic spinning technology for preparing the artificial dura mater, the cell factors can be effectively distributed according to the requirements of concentration and positions, a brain membranization process is the fastest and optimal, and meanwhile, the following adverse reaction of the medicament is reduced because the artificial dura mater can be accurately positioned and quantified by using the biological printing technology.

A toner produced by a method including dissolving or dispersing toner components comprising a resin, a colorant, and a release agent in a solvent to prepare a toner components liquid, discharging the toner components liquid from multiple nozzles provided on a thin film by vibrating the thin film by a mechanical vibration unit to form liquid droplets, and drying the liquid droplets into solid particles of the toner. The particle diameter distribution that is a ratio of a weight average particle diameter to a number average particle diameter of the toner is between 1.00 and 1.15, and a weight average particle diameter of the release agent in the toner is between 1% and 30% of an aperture diameter of the nozzle.

The invention provides thermoplastic elastomer materials used for a bottle cork for manufacturing medicines, a preparation method thereof and a method for applying the bottle cork for manufacturing medicines thereof. The materials are prepared by the following components: styrene copolymer or rubber materials as well as polyolefine matters. The styrene copolymer is PP or PE; besides, the materials also contain a plasticizer and a loading agent, contain or do not contain a compatibilizer, contain or do not contain an antioxidant, contain or do not contain an antistatic agent, contain or do not contain adhesion preventives. The preparation method thereof includes the steps of drying the materials, fusing a reaction kettle, using a plastic extruding machine to extrude the materials, using a cooling water slot to cool and shape the materials, using a hauling machine to haul and cut off the materials, and the like. The thermoplastic elastomer materials provided by the invention have the advantages of stable chemical property, no poison, low polarity and good rebound resilience.

The invention discloses a method that adopts a compound compact and rolls three metal composite boards at the same time. The method comprises the following procedures: (1) the shape and the size of each layer of the metal board are identified according product requirements; (2) each surface that is to be recombined is cleaned: (3) assembly; (4) drilling vacuum pumping; (5) hot rolling and (6) finishing separation. When in assembly, a base metal plate, a multi-layer metal plate, high temperature anti-adhesive agent, a stainless steel plate, the stainless steel plate, the high temperature anti-adhesive agent, the multi-layer metal plate and the base metal plate are arranged in order. Under pressure, the surrounding of two base metal plates are welded with a separator to make space between two base metal plates sealed. The invention has the advantages of little investment and high production efficiency and is used for processing the metal composite plate.

The invention relates to a preparation method of a high-polymer self-adhesive waterproof roll. The technical scheme is as follows: the preparation method comprises the steps of fully coating an SIS (Styrene-Isoprene-Styrene) hot melt pressure sensitive self-adhesive on a main plastic high-polymer waterproof layer by using a hot melt pressure sensitive adhesive coating machine to form an SIS hot melt pressure sensitive self-adhesive layer; then, coating an anti-adhesive isolating membrane on the pressure sensitive self-adhesive layer to prepare a high-polymer self-adhesive waterproof roll product, wherein the main plastic high-polymer waterproof layer is a high-density polyethylene cross laminated film or modified high-density polyethylene film; the anti-adhesive isolating membrane is a silicon oil coated polyurethane isolating membrane. The preparation method has the beneficial effects that firstly, the roll can be permanently and organically combined with the concrete of a structural layer due to the application of the SIS hot melt pressure sensitive self-adhesive, so that no hidden water breakthrough dangers in the intermediate process are caused, and the reliability of a waterproof layer is improved; secondly, the high-polymer self-adhesive waterproof roll is excellent in impact and puncture resistance and capable of bearing the impact of a construction load directly acting on the high-polymer self-adhesive waterproof roll; thirdly, the high-polymer self-adhesive waterproof roll is relatively strong in chemical corrosion resistance and favorable in resistance to alkaline water from concrete; fourthly, the SIS hot melt pressure sensitive self-adhesive is strong in self-healing property.

The invention discloses a quick-dry thin acrylic-acid protective coating, which mainly consists of water, cosolvent, acrylic-acid like emulsion, filler, quick dry agent, hole forming agent, dispersing agent, wetting agent, defoamer, flatting agent and thickener and the like. The invention further discloses an HDPE (high-density polyethylene) self-adhesive film waterproof protective coating layer, which is formed after the quick-dry thin acrylic-acid protective coating is sprayed on a HDPE self-adhesive layer uniformly by a reciprocating mechanical spraying method and drying the same. The quick-dry thin acrylic-acid protective coating is environment-friendly and non-toxic and can be dried quickly and has excellent flatting performance, and an HDPE self-adhesive film waterproof roll prepared by the HDPE self-adhesive film waterproof roll protecting layer has excellent pre-paving anti-adhesive effect with post-cast concrete, and the HDPE self-adhesive film waterproof roll protective layer and the post-cast concrete can be guaranteed to be adhered stably and firmly.

A tissue adhesive formed by reacting an oxidized cationic polysaccharide containing aldehyde groups and amine groups with a multi-arm amine is described. The oxidized cationic polysaccharide-based polymer tissue adhesive may be useful for medical applications including wound closure, supplementing or replacing sutures or staples in internal surgical procedures such as intestinal anastomosis and vascular anastomosis, ophthalmic procedures, drug delivery, anti-adhesive applications and as a bulking agent to treat urinary incontinence. Additionally, due to the presence of the positively charged amine groups on the oxidized polysaccharide, the polymer tissue adhesive disclosed herein may promote wound healing and blood coagulation, and may possess antimicrobial properties.

The invention relates to a preparation method of a hydrogel rapidly crosslinked by enzyme catalysis, and application thereof. A precursor of the hydrogel consists of a mixture (hereinafter referred to as No. 1 solution) of good-biocompatibility macromonomer aqueous solution with an active phenolic hydroxyl unit and dioxygenase aqueous solution which is taken as a catalyst, and the aqueous solution of the precursor can rapidly react to form a 3D polymer cross-linked network after an oxidant (usually low-concentration oxydol, hereinafter referred to as No. 2 solution) is injected. As the No. 1 solution and the No. 2 solution have low-viscosity characteristic, are suitable for being transported and injected, and can rapidly crosslink to form a gel network, the hydrogel can be used for vascular embolization treatment, cancer treatment, family planning operation blocking agents, injectable tissue engineering scaffold materials, soft tissue fillers of human body, controlled release drug carriers, anti-adhesive membranes used in operations and the like after adding one or a plurality of components with specific properties to the No. 1 solution or the No. 2 solution or the gel network.

The invention discloses a high-temperature anti-adhesive coating for producing hard alloy and a preparation method thereof. The high-temperature anti-adhesive coating is used for carbonizing tungsten powder at high temperature and sintering hard alloy, and comprises 5 to 10 weight percent of rare-earth oxide anti-adhesive member, 15 to 20 weight percent of oxide B, 5 to 15 weight percent of high-purity carbon black isolated member, 3 to 5 weight percent of Tween, 3 to 5 weight percent of polyethylene glycol (PEG) and auxiliary film-forming members such as deionized water or ethanol and the like. The coating is prepared by a wet-milling process. When the high-temperature anti-adhesive coating is used for carbonizing the tungsten powder at the high temperature, the oxide B is tungstic oxide; and when the high-temperature anti-adhesive coating is used for sintering the hard alloy, the oxide B is magnesium oxide or aluminum oxide. When the high-temperature anti-adhesive coating is used for preparing coarse or ultra-coarse tungsten carbide powder by carbonization at a temperature of over 1,800 DEG C (high-temperature carbonization with cobalt), diffusion bonding between tungsten carbide consolidated blocks and a graphite boat can be prevented effectively; and when the high-temperature anti-adhesive coating is used for sintering the hard alloy, diffusion bonding between the hard alloy and particularly high-bonding phase hard alloy with the content of a metal bonding agent of more than or equal to 20 weight percent and the graphite boat can be prevented effectively.

The invention discloses an anti-adhesive shoulder fixture for improving the efficiency of an endurance test, which aims to provide a novel test fixture structure to improve the efficiency of the endurance test, prevent the adhesion and the tripping between a specimen and a fixture and between the fixture and a pull rod of a testing machine, and ensure the authenticity and the reliability of the test. The technical scheme of the anti-adhesive shoulder fixture has the following key points that: the fixture adopts a shoulder type structure to prevent the adhesion and the tripping between the specimen and the fixture and the adhesion and the tripping between the fixture and the pull rod of the testing machine; a shoulder type serial connector is designed, and two specimens are connected in series and are synchronously tested on one testing machine so as to improve test efficiency; a shoulder large pull head adopts K002 high-temperature alloy, and the shoulder fixture and the shoulder type serial connector adopt directional high-temperature alloy DZ22 or single crystal high-temperature alloy DD3 to improve the applicable test temperature of the fixture to 1200 DEG C; and the fixture has simple operation and quick and convenient clamping, ensures the concentricity, and is applicable to different models of endurance testing machines produced by different testing machine manufacturers.

Tissue adhesives formed by crosslinking albumin and / or gelatin with certain polyamines and / or polycarboxylates using a water-soluble carbodiimide are disclosed. The use of the tissue adhesives for medical and veterinary applications such as topical wound closure; and surgical procedures, such as intestinal anastomosis, vascular anastomosis, tissue repair, and ophthalmic procedures; drug delivery; anti-adhesive applications; and as a bulking agent to treat urinary incontinence are described.

The invention relates to a matte BOPP (Biaxially-oriented Polypropylene) film for leather transferring and a preparation method thereof. The matte BOPP film consists of an inner surface layer, a core layer and an outer surface layer, and is prepared by coextrusion and two-way stretching of the inner surface layer, the core layer and the outer surface, wherein the inner surface layer comprises the following components in percentage by weight: 97.5-98.5% of polypropylene and 1.5-2.5% of adhesive; the core layer comprises the following components in percentage by weight: 98.0-98.4% of polypropylene, 1.0-1.2% of antistatic agent and 0.4-1.0% of slipping agent; the outer surface layer adopts a delustering material which comprises the following components in percentage by weight: 54-56% of polyethylene, 43.7-45.7% of high-density polyethylene and 0.3% of antioxidant. The matte BOPP film and the preparation method have the advantages that the selection and matching of the materials are reasonable, the selected polypropylene material is good in processing performance and high in mechanical strength; the prepared BOPP film is large in elastic modulus and low in heat shrinkage rate; the performance indexes such as haze and glossiness of the outer surface layer are excellent.

The invention discloses a preparation method of re-dispersible latex powder of acrylic acid. The preparation method comprises the preparation of the re-dispersible latex powder emulsion of acrylic acid and the spray drying of the re-dispersible latex powder emulsion of acrylic acid. The re-dispersible latex powder emulsion of acrylic acid adopts design of core-shell particles and is obtained by acrylic acid monomer in a way of emulsion polymerization. When the emulsion is sprayed and dried, a mineral anti-adhesive agent is added to obtain the re-dispersible latex powder of acrylic acid. The re-dispersible latex powder of acrylic acid can be added in concrete and mortar to improve the compressive strength, rupture strength, wear resistance, toughness, adhesion strength, water-retention capacity and constructability of the concrete and mortar.

The invention relates to coating compositions having anti-adhesion and dirt repellency properties, these compositions being admixed as additive with from 0.1 to 10% by weight, based on the solids content of the coating composition, of a branched polymer which possesses a weight-average molecular weight of from 2000 to 200,000 and comprises a polymeric base molecule and also polydiorganosiloxane side chains which are bonded covalently to the base molecule via Si-C bonds, have a weight-average molecular weight of between 1000 and 30,000, and whose fraction of the total weight of the branched polymer is from 5 to 25% by weight. The present invention further relates to polymeric moulding compounds having anti-adhesion and dirt repellency properties, to which this branched polymer is added as additive in an amount of from 0.1 to 10% by weight, based on the total weight of the polymeric moulding compounds. The invention additionally relates to the use of the branched polymers as additives for coating compositions and polymeric moulding compounds.

The invention discloses a regenerated silk fibroin gel mask and a preparation method thereof. The specific preparation method comprises the following steps: (1) directly dissolving degummed silk into a formic acid solution containing salt, and drying to obtain a silk fibroin mask containing salt; and (2) directly soaking the dried mask into an alcoholic solution or water, so as to prepare the regenerated silk fibroin gel mask. Compared with the prior art, the gel mask has the advantages of traditional silk fibroin mask and hydrogel, is transparent, excellent in mechanical property and high in moisture content, and simultaneously has a biomimetic nanometer fiber structure, good degradability and good biocompatibility; and in addition, the gel mask is simple in preparation method, short in flow and easy to achieve mass production. The gel mask has excellent physical and chemical properties and biological characteristics, so that the regenerated silk fibroin gel mask has a wide application prospect in the fields of cosmetics and regenerative medicines, such as masks, skin dressing, dura mater cerebralis, corneas, anti-adhesive films, nerve sheath pipes and the like.

The invention discloses a stent type silk fibroin film insoluble in water, and preparation and application of the stent type silk fibroin film. A preparation method includes the steps of placing silk fibroin solution in a smooth, flat and horizontal mold, and obtaining a basilar film by humid and heat crosslinking; and laying the silk fibroin solution on the surface of the basilar film and forming the stent type silk fibroin film insoluble in water after freezing, drying and humid and heat crosslinking. Silk fibroin is used as a raw material, and biocompatibility is good; a preparation process is non-toxic and environment-friendly, and the thickness of the film and the aperture of a stent layer are easy to control; the film is soft in a moist environment, the basilar film is compact, and cells, microorganisms and biomacromolecules cannot penetrate through the basilar film; the stent layer is in the shape of a porous sponge, and is beneficial to fixation of the film, hemostasis of a wound and regeneration of transmitting tissues; and the film has a wide market in the field of anti-adhesive films and artificial film patches.

The invention relates to a method for producing mellow concave-convex rod suspension. Wherein, it comprises mixing convex-concave rod clay, magnesia, sodium silicate, and macrogol, emerging, compressing, drying, grinding, and packing. The invention has low cost without using water in preparing casting coat, with suspension rate, non deposit, and high anti-adhesive property.

The invention discloses a once-forming non-gelatinizing cold sticking protective layer, which comprises the following parts: corona treatment layer, mesosphere, adhesive coating, wherein the corona treatment layer consists of isotactic homopolymerization polypropylene, polypropylene , adhesion preventives and slip additive; the mesosphere consists of polyethylene with low density, linearity polyethylene with low density; the adhesive coating consists of linearity polyethylene with low density, POE and tackifier.

The invention relates to a coating combination, especially a coating used for producing hard alloy, adopting the following components in the proportion: graphite powder 20-40%, tween 4-8%, polyvinyl alcohol 0.2-1.0%, formaldehyde 0.05-0.5%, alumina powder 1-5%, water-soluble glue 0.1-1.0%, and distilled water 50-70%; it has the characters of strong adhesion, being easy to uniformly disperse as being coated, excellent anti-adhesive property to hard alloy product in the vacuum-sintering process, and its preparing process is simple, its cost is low, and it can strengthen the quality stability of the hard alloy products, beneficial to large-scale industrialized production of hard alloys, and its economic benefits are good.

The present invention relates to a product comprising at least two antibiofilm agents wherein at least one of the antibiofilm agents is an antimicrobial peptide. The second antibiofilm agent is generally a dispersant or an anti-adhesive agent. There is also provided the use of the product in the treatment of a microbial infection.