Application of houttuynoid D in the preparation of anti-platelet aggregation drugs
An anti-platelet aggregation and drug technology, which can be used in drug combinations, blood diseases, pharmaceutical formulations, etc., and can solve the problems of small adverse reactions and urgency.
Active Publication Date: 2015-08-19
东台海滨科技创业园管理有限公司
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- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Currently commonly used antiplatelet drugs have severe adverse reactions, so it is urgent to develop new effective drugs for the treatment and prevention of platelet aggregation with less adverse reactions
Method used
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Experimental program
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Effect test
Embodiment 1
[0011] Embodiment 1: the preparation of compound Houttuynoid D tablet involved in the present invention:
[0012] Take 20 grams of compound Houttuynoid D, add 180 grams of conventional excipients for tablet preparation, mix well, and make 1000 tablets with a conventional tablet press machine.
Embodiment 2
[0013] Embodiment 2: the preparation of the compound Houttuynoid D capsule involved in the present invention:
[0014] Take 20 grams of compound Houttuynoid D, add conventional auxiliary materials for preparing capsules such as 180 grams of starch, mix well, and pack into capsules to make 1000 tablets.
[0015] The following pharmacodynamic experiments will further illustrate its drug activity.
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The invention relates to an application of Houttuynoid D in preparing an anti-platelet aggregation medicine. The application of the Houttuynoid D in preparing an anti-platelet aggregation medicine is revealed for the first time; since a brand new skeleton type is adopted and the anti-platelet aggregation activity thereof is unexpectedly strong, the possibility of other compounds giving any prompt is avoided, and the Houttuynoid D has outstanding substantive features; and a remarkable progress is made in applying the Houttuynoid D to the platelet aggregation resistance.
Description
technical field [0001] The present invention relates to the new application of Houttuynoid D, more specifically relates to the application of the compound in the preparation of anti-platelet aggregation drugs. Background technique [0002] The basic physiological functions of platelets are adhesion, aggregation, release and secretion of granule contents (such as ATP, 5-hydroxytryptamine). After activation, platelets can provide a phospholipid surface, promote blood coagulation, and form a thrombus composed of fibrin surrounding platelets. Therefore, as a formed component of blood, platelets play a very important role in the process of physiological hemostasis and pathological thrombus formation. Clinical studies have shown that common cardiovascular and cerebrovascular diseases such as hypertension, angina pectoris, myocardial infarction, cerebral infarction and cerebral hemorrhage are basically related to changes in platelet function and abnormal hemorheology. Currently c...
Claims
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IPC IPC(8): A61K31/7048A61P7/02
Inventor 丁圣雨
Owner 东台海滨科技创业园管理有限公司