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Traditional Chinese medicine effective part composition for treating primary adrenocortical insufficiency

An adrenal cortex, effective part technology, applied in the direction of drug combinations, medical preparations containing active ingredients, pharmaceutical formulations, etc.

Inactive Publication Date: 2013-12-11
张群
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Modern western medicine still lacks specific treatments

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] 25g clover, 22g snakeberry, 20g ground root, 15g pearl ginseng, 12g ramie root and 6g orange core, add 16 times the amount of water after drying, boil with strong fire, then decoct with slow fire for 120min, the obtained decoction is ready for use.

Embodiment 2

[0014] Clinical observation of 200 patients with primary adrenal insufficiency. All patients were diagnosed with primary adrenal insufficiency by clinical diagnosis. Take embodiment 1 gained decoction to the patient, 1 day 2 times, take before meal sooner or later, continuous 30 days.

[0015] The statistical results of patients taking the decoction gained in Example 1 are shown in Table 1. Significant effect in Table 1 includes cure and effectiveness, wherein, cure means that the clinical symptoms have basically disappeared, physical strength has recovered, and people have been able to work as ordinary people, and the laboratory test indicators are normal or close to normal; effective means that the clinical symptoms have basically disappeared, and the laboratory tests Indicators have improved significantly. Ineffective means that there is no significant change in clinical symptoms and no progress in laboratory indicators.

[0016] Table 1

[0017] Number of cas...

Embodiment 3

[0020] The decoction prepared in Example 1 was used to administer ICR mice with a body weight of 20-25 g, half male and half female, and the administration was continued for 60 days.

[0021] After preliminary testing, the toxicity of the decoction prepared in Example 1 was very low, and the LD50 could not be detected, so the maximum daily dose was determined for mice. The maximum dosage is 400ml / d, and no case of poisoning death was observed after 60 days, and all survived healthy, thus proving that the decoction made from the composition of the present invention has no toxic and side effects on the human body.

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PUM

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Abstract

The invention discloses a traditional Chinese medicine effective part composition for treating primary adrenocortical insufficiency. The traditional Chinese medicine effective part composition comprises the following raw materials according to certain parts by weight: hemsley rockvine root, mock-strawberry, air-plant herb, rhizoma panacis majoris, ramie root and tangerine seed. The traditional Chinese medicine effective part composition has the effects of warming the kidney to tonify Yang, melting Qi for dieresis, strengthening the spleen to transport, nourishing the kidney and liver, nourishing yin to clear heat, tonifying Qi and activating blood circulation, and has obvious curative effects, no negative side effect and high security in treatment of primary adrenocortical insufficiency.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine compositions, in particular to a composition of effective parts of traditional Chinese medicines for treating primary adrenal insufficiency. Background technique [0002] Primary adrenal insufficiency, also known as Addison's disease, is caused by lesions in the adrenal cortex itself. The main causes are tuberculosis, cancer and idiopathic atrophy. In my country and Japan, tuberculosis is the main cause of adrenal tissue destruction, accounting for about 68% of all cases. In recent years, due to the decrease in the number of cases of tuberculosis infection, the occurrence of this disease has also decreased one after another, making it relatively rare. Due to the large reserve capacity of the adrenal gland, it is generally necessary to wait for the destruction of the adrenal gland tissue to reach more than 80-90% before clinically obvious symptoms of adrenal cortical insufficiency appe...

Claims

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Application Information

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IPC IPC(8): A61K36/87A61K36/752A61P5/38
Inventor 张群
Owner 张群