Check patentability & draft patents in minutes with Patsnap Eureka AI!

A kind of cyclic synthetic polypeptide f and its antibacterial and antiviral application

A technology for synthesizing peptides and anti-viruses, which can be applied in the direction of anti-viral agents, anti-bacterial drugs, and medical preparations containing active ingredients, etc. It can solve the problem of fundamentally controlling the diseases of mariculture animals and hindering the healthy development of aquaculture production, etc. question

Active Publication Date: 2016-05-11
INST OF OCEANOLOGY - CHINESE ACAD OF SCI
View PDF3 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Shrimp farming occupies an important position in my country's aquaculture industry. In recent years, the disease problems in the shrimp farming process have seriously hindered the healthy development of its farming production. The abuse of antibiotics and the deterioration of the environment have made it difficult for marine animals to suffer from diseases. fundamentally under control

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A kind of cyclic synthetic polypeptide f and its antibacterial and antiviral application
  • A kind of cyclic synthetic polypeptide f and its antibacterial and antiviral application
  • A kind of cyclic synthetic polypeptide f and its antibacterial and antiviral application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0023] The present invention is described in further detail below in conjunction with embodiment.

[0024] A chemically synthesized prawn cyclic polypeptide F with obvious antibacterial and antiviral activities, its sequence and source sequence information are as follows:

[0025] (1) Information of SEQ ID No.1

[0026] (a) Sequential features

[0027] * Length: 24 amino acids

[0028] *Type: amino acid

[0029] * Chain type: single chain

[0030] *Topology: ring, disulfide bond formed between two cysteines

[0031] * Spatial structure: has 1) figure 1 Skeleton structure shown: Two cysteines are connected by disulfide bonds to form a ring structure, where the disulfide bonds are shown in darker black, and the C skeleton and other atoms are shown in gray; and 2) figure 2 The spatial structure shown: the polypeptide sequence forms two connected β-sheet structures.

[0032] (b) Molecule type: protein

[0033] Sequence description: SEQIDNo.1

[0034] Ac-Sc(CKYSQKPSFKRWQL...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a circular synthesized polypeptide F and antibacterial and antivirus application thereof. The circular synthesized polypeptide F has structural characteristics and an amino acid sequence represented by SEQ ID NO:1 in a sequence list; the circular synthesized polypeptide D is derived from the LPS binding domain of Chinese Fenneropenaeus merguiensis anti-lipopolysaccharide factor ALFFc represented by SEQ ID NO:2 in the sequence list; by performing a biological function verification in vitro on the circular synthesized polypeptide F, the circular synthesized polypeptide F is verified to have a very strong inhibition actions to the growth and proliferation of gram-positive bacteria, gram-negative bacteria or viruses.

Description

technical field [0001] The present invention relates to a cyclic synthetic polypeptide F and its antibacterial and antiviral applications, in particular to a synthetic cyclic polypeptide derived from the lipopolysaccharide (LPS) binding domain of Penaeus prawn anti-lipopolysaccharide factor ALFFc and Its antibacterial and antiviral applications. Background technique [0002] Shrimp farming occupies an important position in my country's aquaculture industry. In recent years, the disease problems in the shrimp farming process have seriously hindered the healthy development of its farming production. The abuse of antibiotics and the deterioration of the environment have made it difficult for marine animals to suffer from diseases. fundamentally under control. [0003] Antimicrobial peptides (proteins) are considered to be important effector molecules for fish, shrimp, shellfish, etc. to defend against infection by exogenous pathogens such as bacteria and viruses, and play an im...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): C07K14/435A61K38/17A61P31/04A61P31/20
CPCA61K38/17C07K14/43509
Inventor 李诗豪李富花郭书悦相建海
Owner INST OF OCEANOLOGY - CHINESE ACAD OF SCI
Features
  • R&D
  • Intellectual Property
  • Life Sciences
  • Materials
  • Tech Scout
Why Patsnap Eureka
  • Unparalleled Data Quality
  • Higher Quality Content
  • 60% Fewer Hallucinations
Social media
Patsnap Eureka Blog
Learn More

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2025 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com