Multifunctional workstation for automatically detecting outflow of cholesterol and other analyte cells with high throughput

Abstract

The invention discloses a multifunctional workstation for automatically detecting the outflow of cholesterol and other analyte cells with high throughput. The multifunctional workstation comprises a constant-temperature short-period incubator (1), a cell washing and sample loading platform (2), a sample filtering platform (3), a sampling and collecting platform (4), a mechanical hand multi-branch distribution system (5), and a software control system and a display interface of the workstation. The workstation is reasonable in structural design and high throughput and automation can be realized in a manual test so that a plurality of clinical samples can be treated and the working efficiency is improved; the aims of clinical applications and rapid screening of the samples are realized. The multifunctional workstation can be widely used for measuring cell outflow dynamic characteristics of other molecules, such proteins, lipids, RNA (Ribonucleic Acid), ions, saccharides, hormones, vitamins, and metabolites; the application range is wide.

Description

technical field [0001] The invention relates to a high-throughput analysis device for biomolecules, in particular to an activity that can detect cholesterol efflux from HDL cells, and can also be used for other molecules / compounds, such as proteins, lipids, ions, hormones, metabolites, etc. Quantification of flow can be widely used in biological research, clinical diagnosis and drug development of high-throughput automated biomolecular multifunctional analysis system. Background technique [0002] Cardiovascular disease is a major threat to human health, with high morbidity and mortality, and it is increasing year by year, especially in rapidly developing economies such as China. According to the Cardiovascular Prevention Research Center of the Ministry of Health, with the improvement of our living standards and the aging population, the incidence of cardiovascular disease is increasing at a rate of 30% every year. [0003] Atherosclerosis is the leading cause of cardiovas...

AI Technical Summary

Problems solved by technology

At present, this experiment can only be carried out manually in the laboratory. Manual operation involves a lot of work such as plasma dilution, cell washing, and sample filtration. This experimental method is time-consuming and prone to manual errors; Adding steps not only limits the sample size of each test, but also consumes a lot of consumables, increasing the cost of testing

Due to the above shortcomings, HDL functional testing has limited application in clinical diagnosis or biotechnology / drug development, and cannot be used for high-throughput screening required by large samples

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