Small nucleic acid whitening and freckle-removing cream, and preparation method thereof

A technology of whitening and removing freckles and small nucleic acids, which is applied in the field of whitening and removing freckles and its preparation, which can solve the problems of high pigment content and achieve the effects of reducing plaques, non-toxic side effects, and reducing oxidation

Active Publication Date: 2014-04-09
JIANGSU GENECON BIOLOGICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Aiming at the deficiencies of the prior art, the present invention provides a safe and effective small nucleic acid whitening and spot-removing cream and its preparation method, which can effectively solve skin problems caused by excessive pigment content in skin cells, such as plaques caused by fake and inferior cosmetics, sun exposure freckles, chloasma, butterfly spots, age spots and freckles, etc. This product is easy to use, effective, safe and reliable

Method used

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  • Small nucleic acid whitening and freckle-removing cream, and preparation method thereof
  • Small nucleic acid whitening and freckle-removing cream, and preparation method thereof
  • Small nucleic acid whitening and freckle-removing cream, and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] A small nucleic acid whitening and freckle-removing cream, comprising the following components by weight percentage: small nucleic acid active ingredient 0.005%, transdermal penetrating membrane peptide 0.195%, polyhydrogenated polydecene 3%, sorbitan olivate 3%, stearin Acid 1.5%, Cetyl Alcohol 2%, Dimethicone 1%, Cyclopentasiloxane 2%, Bis-PEG-15 Methyl Ether Dimethicone 5%, 1. 3% 2-pentanediol, 0.4% ammonium acryloyldimethyl taurate / VP copolymer, 3% shea butter, 0.15% essence, 4% hydrogenated ethylhexyl olive oil, EDTA Sodium 0.1%, lipoic acid 1%, glycerin 5%, hyaluronic acid 0.05%, and deionized water as the balance.

[0030] Wherein, the small nucleic acid active ingredient is composed of 30% MITF-sRNA, 60% TYR-sRNA and 10% TYRP-sRNA accounting for the total weight of the small nucleic acid active ingredient; The percentage of the total weight of penetrating peptides is composed of 85% arginine 9-mer, 5% arginine 6-mer, 5% arginine 7-mer and 5% arginine 8-mer . ...

Embodiment 2

[0032] A small nucleic acid whitening and freckle-removing cream, comprising the following components by weight percentage: small nucleic acid active ingredient 0.001%, transdermal penetrating membrane peptide 0.059%, polyhydrogenated polydecene 2.5%, sorbitan olive oil 2.5%, stearin Acid 2.5%, Cetyl Alcohol 2%, Dimethicone 0.5%, Cyclopentasiloxane 1%, Bis-PEG-15 Methyl Ether Dimethicone 3%, 1. 4% 2-pentanediol, 0.5% ammonium acryloyldimethyl taurate / VP copolymer, 5% shea butter, 0.15% essence, 3% hydrogenated ethylhexyl olive oil, EDTA Sodium 0.1%, lipoic acid 1%, glycerin 5%, hyaluronic acid 0.1%, and deionized water as the balance.

[0033] Wherein, the small nucleic acid active ingredient is composed of 60% MITF-sRNA, 30% TYR-sRNA and 10% TYRP-sRNA accounting for the total weight of the small nucleic acid active ingredient; The percentage of the total weight of penetrating peptides is composed of 90% arginine 9-mer, 3% arginine 6-mer, 2% arginine 7-mer and 5% arginine 8-m...

Embodiment 3

[0035]A small nucleic acid whitening and freckle-removing emulsion, comprising the following components by weight percentage: small nucleic acid active ingredient 0.01%, transdermal penetrating membrane peptide 0.39%, polyhydrogenated polydecene 2%, sorbitan olive oil 1%, stearin Acid 2%, Cetyl Alcohol 2%, Dimethicone 1.5%, Cyclopentasiloxane 1.5%, Bis-PEG-15 Methyl Ether Dimethicone 2%, 1. 2-pentanediol 2%, ammonium acryloyldimethyl taurate / VP copolymer 0.5%, shea butter 2%, essence 0.15%, hydrogenated ethylhexyl olive oil 2%, EDTA Sodium 0.1%, lipoic acid 1.5%, glycerin 5%, hyaluronic acid 0.1%, and the balance is deionized water.

[0036] Wherein, the small nucleic acid active ingredient is composed of 90% MITF-sRNA, 5% TYR-sRNA and 5% TYRP-sRNA accounting for the total weight of the small nucleic acid active ingredient; The percentage of the total weight of penetrating peptides is composed of 85% arginine 9-mer, 3% arginine 6-mer, 2% arginine 7-mer and 10% arginine 8-mer ...

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PUM

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Abstract

The invention relates to a small nucleic acid whitening and freckle-removing cream. The whitening and freckle-removing cream comprises the following components by mass: 0.001-0.01% of small nucleic acid active ingredients, 0.04-0.5% of a transdermal cell-penetrating peptide and 99.49-99.959% of a cosmetic auxiliary material. The whitening and freckle-removing cream provided by the invention can efficiently inhibiting formation of melanin, and has the effects of moisturizing and moistening skins, resisting aging and removing winkles and stimulating skin metabolism, so as to achieve a comprehensive regulation of whitening and freckle-removing effects.

Description

technical field [0001] The invention relates to a whitening and freckle-removing cream and a preparation method thereof. Background technique [0002] For a long time, whitening and freckle removal has been the goal pursued by most beauty-loving women. The existing whitening methods are as follows: The earliest method to whiten the skin is a peeling and bleaching method: different peeling and bleaching formulas can be used in different ways. The degree of peeling can usually be divided into three types, namely deep, medium and shallow peeling methods. Commonly used formulations are some acids and alcohols. The first two are dangerous and not suitable for making common cosmetics. And the third one is safe and can remove local hyperpigmentation in a limited way. Then, people gradually realized that the difference of dark and light skin color is related to the level of tyrosinase activity in melanocytes, so methods and corresponding products for skin whitening containing var...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/64A61K8/60A61K8/96A61Q19/00
Inventor 黄兵殷勤伟
Owner JIANGSU GENECON BIOLOGICAL TECH
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