Fixing device for magnetic resonance examination on laboratory mouse and application method thereof

Abstract

The invention discloses a fixing device for magnetic resonance examination on a laboratory mouse and an application method thereof. The fixing device comprises a round tube main body, wherein a first opening is formed in one end of the round tube main body, a conical surface is arranged on the other end of the round tube main body, a second opening is formed in the conical surface, and a through hole is formed in the wall of the round tube main body. A base is arranged at the bottom of the round tube main body, a concave surface is arranged at the top end of the base, the outer wall of the concave surface is matched with the outer wall of the round tube main body, the bottom end of the base is a plane, the round tube main body and the base are made of polypropylene plastics, and length scale marks are arranged on the outer wall of the round tube main body. The application method comprises the steps that an operator holds the tail of the narcotized mouse and put the mouse into the round tube main body, the nose of the mouse is put into the second opening in the conical surface of the round tube main body, and the tail of the mouse is positioned out of the round tube; the round tube main body with the mouse is arranged on the base; the mouse is taken out of the round tube after magnetic resonance examination and raised continuously after coming to itself. The fixing device is easy to operate and capable of increasing the survival rate of the mouse, reducing experiment cost and improving imaging quality.

Description

technical field [0001] The invention relates to an experimental rat fixing device and a using method thereof, in particular to a lab mouse fixing device for magnetic resonance examination and a using method thereof. Background technique [0002] Experimental mice (mice and nude mice) are commonly used mammalian experimental animals, and are often used in the research of radiology, immunology, and tumor leukemia. However, most of them focus on the magnetic resonance imaging of a single mouse / nude mouse, and the number of experimental mice is often large, the imaging time of magnetic resonance is long, and the cost is high. The cost of magnetic resonance examination of large sample size experimental mice is relatively high High, the actual operation is more difficult. Simultaneous magnetic resonance imaging of multiple mice can not only reduce the inspection cost, but also increase the reliability of the inspection results. However, the technical problem of multi-rat MRI exa...

AI Technical Summary

Problems solved by technology

However, the technical problem of multi-rat MRI examination is the fixation and body placement of the experimental rats.

Because mice or nude mice are small in size and soft in body, they are not easy to fix. At present, coils are wound on the outer surface of mice, but winding coils will often flatten experimental mice, reduce the survival rate of experimental mice, increase the cost of experiments, and Increase scanning difficulty and image quality

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