Diabetic foot ulcer external Chinese medicine composition, preparation method and application thereof

A technology for a diabetic foot ulcer and a composition is applied in the field of externally used traditional Chinese medicine compositions for diabetic foot ulcers, which can solve the problems of unobserved long-term curative effects, poor repeatability of curative effects, and low quality of diabetic foot ulcers. The effect of eliminating edema and improving blood circulation

Inactive Publication Date: 2017-08-11
THE FIRST AFFILIATED HOSPITAL OF THIRD MILITARY MEDICAL UNIVERSITY OF PLA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] (4) Surgical operations and interventional therapy: Arterial stents, balloon dilation, arterial plaque ablation, arterial plaque atherectomy, artificial vascular bypass, etc. require sophisticated and expensive equipment, heavy trauma, high risk, high cost, and many complications , high mortality, poor patient compliance
[0007] (5) Stem cell therapy: The required equipment is sophisticated and expensive, and due to ethical restrictions, most hospitals cannot carry out it, and the long-term efficacy remains to be seen
However, the evidence-based evidence for the efficacy of these therapies is insufficient and has not been recognized by the international and domestic Western medical circles
The reasons are as follows: (1) The quality of clinical research on the treatment of diabetic foot ulcers with traditional Chinese medicine is not high, and the repeatability of its curative effect is poor, so the credibility has been questioned; In one aspect, the advantages compared with Western medicine are not clear; (3) There is no strict clinical research evidence for the effect of integrated Chinese and Western medicine
[0015] Although the existing traditional Chinese medicines for external application on diabetic feet have a certain curative effect, their onset is slow, the course of treatment is long, and their safety and curative effect are poor.

Method used

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  • Diabetic foot ulcer external Chinese medicine composition, preparation method and application thereof
  • Diabetic foot ulcer external Chinese medicine composition, preparation method and application thereof

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preparation example Construction

[0046] The invention also discloses a preparation method of a traditional Chinese medicine composition for diabetic foot ulcer, comprising the following steps:

[0047] Add coptis, Panax notoginseng, comfrey, Salvia miltiorrhiza, Cortex Phellodendri, frankincense, and myrrh to the sesame oil according to the set weight, soak and cook until slightly bitter, filter impurities and continue to cook until the sesame oil boils, and then add the set weight in sequence 2 parts of dried blood and beeswax are stirred until they are completely melted, and finally a set weight part of calcined gypsum is added and stirred evenly to obtain the external Chinese medicine composition for diabetic foot ulcer.

[0048] In this embodiment, Coptidis Rhizoma, Panax notoginseng, Comfrey, Salvia miltiorrhiza, Cortex Phellodendron, Frankincense, and Myrrh are added to the sesame oil and soaked for 3-8 days according to the set weight portion.

[0049] In the present embodiment, it is preferably soaked...

Embodiment 1

[0053] In the external Chinese medicine composition for diabetic foot ulcer of the present embodiment, the raw materials of the Chinese medicine composition include the following components by weight: 18 parts of Coptidis Rhizome, 9 parts of Sanqi, 18 parts of Comfrey, 9 parts of Salvia Miltiorrhiza, 12 parts of Phellodendron Phellodendri, 6 parts of Frankincense, 6 parts of myrrh, 6 parts of dried blood, 6 parts of beeswax, and 18 parts of calcined plaster.

[0054] Soak Coptis chinensis, Panax notoginseng, Comfrey, Salvia miltiorrhiza, Cortex Phellodendri, frankincense, and myrrh in sesame oil in proportion for 6 days; Add dried blood and beeswax and keep stirring until it is completely melted; finally, add calcined gypsum, let it cool down slightly and keep stirring until it becomes a uniform paste, then pack it in sterile containers and put it in a clean environment for later use.

Embodiment 2

[0056] The external Chinese medicine composition for diabetic foot ulcer of the present embodiment, the raw material of the Chinese medicine composition comprises the following components by weight: 15 parts of Coptidis Rhizoma, 5 parts of Radix Notoginseng, 15 parts of Comfrey, 3 parts of Salvia Miltiorrhiza, 7 parts of Cortex Phellodendri, 1 part of Frankincense, 1 part of myrrh, 1 part of blood, 1 part of beeswax, and 15 parts of calcined plaster.

[0057] Soak Coptis chinensis, Panax notoginseng, Comfrey, Salvia miltiorrhiza, Cortex Phellodendri, frankincense, and myrrh in sesame oil in proportion for 3 days; Add dried blood and beeswax and keep stirring until it is completely melted; finally, add calcined gypsum, let it cool down slightly and keep stirring until it becomes a uniform paste, then pack it in sterile containers and put it in a clean environment for later use.

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Abstract

The invention discloses a traditional Chinese medicine composition for external use for treating diabetic foot ulcer. The traditional Chinese medicine composition is prepared from the raw materials in parts by weight: coptis chinensis, pseudo-ginseng, lithospermum, salvia miltiorrhiza, golden cypress, frankincense, myrrh, dragon blood, beewax and calcined gypsum, wherein the raw materials have synergistic effects for recovering the elasticity for the blood vessels by clearing away heat and toxic materials and promoting blood circulation to remove blood stasis; the insufficient blood supply can trend to be normal in a slow process; gene regulation elements and effective active molecules in the traditional Chinese medicine raw materials can enter diseased parts of the blood; in a smooth and steady regulating process, the traditional Chinese medicine composition for external use can be used for repairing damaged tissues and organs of the body by improving liver and kidney mainly, controlling the diabetic pathogenesis step by step, regulating the human body nervous system and promoting blood circulation, playing a coordination and comprehensive treatment role, changing the diabetic pathogenesis radically and recovering the body; the traditional Chinese medicine composition for external use has the effects of removing slough and promoting growth of tissue regeneration, warming the meridians, tonifying qi and activating blood, alleviating phishom limb pain, controlling ulcer surface infection, improving local microcirculation, enhancing bidirectional transfer function of endothelial cells, improving conduction velocity of peripheral nerve and promoting the repair of the tissues and the healing of the wound surfaces.

Description

technical field [0001] The invention relates to a medicine for treating diabetes, in particular to a traditional Chinese medicine composition for external use on diabetic foot ulcer, a preparation method and application thereof. Background technique [0002] Diabetic foot is a common complication of diabetes, which seriously affects the labor ability and quality of life of patients. Diabetic foot ulcer is the main clinical manifestation of diabetic foot, and its amputation rate is 15-20 times that of non-diabetic patients. Studies have shown that the amputation-related all-cause mortality rate of diabetic patients is more than 5 times higher than that of non-diabetic patients. There are about 92 million diabetic patients in my country, and the incidence of diabetic foot is about 0.9%-14.5%. Diabetic foot has brought a heavy burden to social medical resources. In Western countries, the cost of diabetic foot ulcers is $16,000-27,000 per patient, and the medical cost of amput...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/889A61K36/896A61P3/10A61P17/02A61P9/14A61K35/644A61K33/06
Inventor 陈兵张玲吴绮楠甘霞光李树法
Owner THE FIRST AFFILIATED HOSPITAL OF THIRD MILITARY MEDICAL UNIVERSITY OF PLA
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