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Traditional Chinese medicine composition for treating damp-heat type yellow and white scour of piglets as well as preparation and preparation method thereof

A composition and moist heat technology, applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc., can solve the problems of increased drug resistance, reduced curative effect, ineffectiveness, etc., and achieve the effect of no drug resistance

Inactive Publication Date: 2014-09-03
CHONGQING ACAD OF ANIMAL SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Generally, diarrhea that occurs within 7 days after birth is called yellow dysentery, while diarrhea that occurs over 7 days after birth is called white diarrhea. Infectious diseases, if not treated in time, can easily lead to the death of piglets and bring huge economic losses to pig farms and farmers
There are many drugs currently used to treat this type of disease, but mainly chemical drugs. Due to long-term clinical irrational drug use, drug resistance has increased year by year, and its curative effect has gradually decreased or even become ineffective.

Method used

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  • Traditional Chinese medicine composition for treating damp-heat type yellow and white scour of piglets as well as preparation and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Weigh 300 grams of Coptis chinensis, 400 grams of black plum and 300 grams of three needles, mix them and coarsely crush them, add water to decoct three times, add water for the first time to 10 times the original drug amount, add water for the second time to 8 times the original drug amount, and add water for three times Add water to 6 times the amount of the original medicine, decoct for 1 hour each time, combine the decoctions of the three decoctions, filter, then heat and concentrate the filtrate until the content of the original medicine is 0.8g / ml, and store it at 4°C for 48 hours. Centrifuge at 10,000 rpm for 30 minutes, add preservative to the supernatant, boil for 5 minutes, and filter to obtain the oral liquid.

Embodiment 2

[0021] Chinese medicine oral liquid of the present invention treats the clinical trial effect verification of yellow and white scour of piglets:

[0022] Select 140 purebred Yorkie piglets with similar parity, age, and litter size, and were diagnosed with yellow and white scour caused by damp heat, and divided them into 3 groups, 60 pigs in the Chinese medicine oral liquid test group, and 60 Yang Shuhua oral liquid control group. The medicine control group was 20. The dosage of poplar flower oral liquid is 10ml / head, and the test group of traditional Chinese medicine oral liquid (oral liquid prepared in Example 1) is 5ml / head, taken 2 times a day, 3 days as a course of treatment.

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Abstract

The invention discloses a traditional Chinese medicine composition for treating damp-heat type yellow and white scour of piglets. The traditional Chinese medicine composition consists of the following components in parts by weight: 1-5 parts of golden thread, 2-6 parts of dark plum fruit and 2-5 parts of berberis julianae schneid. The invention also discloses an oral liquid preparation prepared from the traditional Chinese medicine composition and a preparation method of the oral liquid preparation. The preparation method comprises the steps of mixing dark plum fruit, golden thread and berberis julianae schneid in proportion, crushing, then adding water for boiling, then filtering decoction, concentrating filtrate to ensure that the dose of primary medicaments contained in per 1000ml is 500-1000g, refrigerating and placing, then centrifuging, taking supernatant liquor, adding preservatives, boiling, and filtering to prepare oral liquid. The traditional Chinese medicine composition disclosed by the invention combines the three medicaments namely golden thread, golden thread and berberis julianae schneid, has the effects of clearing away heat and drying dampness, and astringing to arrest diarrhea, and is mainly used for treating dysentery, diarrhea and the like caused by dampness-heat. Clinical trials show that when the traditional Chinese medicine oral liquid disclosed by the invention is used for treating yellow and white scour caused by dampness-heat of the piglets, the recovery rate can reach more than 90%, and medicament tolerance can not be generated.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese veterinary medicines, and in particular relates to a traditional Chinese medicine composition for treating damp-heat yellow and white scour of piglets, as well as a preparation and a preparation method thereof. Background technique [0002] Piglet yellow and white scour is the abbreviation of piglet yellow scour and pullorum. Generally, diarrhea that occurs within 7 days after birth is called yellow dysentery, while diarrhea that occurs over 7 days after birth is called white diarrhea. Infectious diseases, if not treated in time, can easily lead to the death of piglets and bring huge economic losses to pig farms and farmers. There are many drugs currently used to treat this type of disease, but mainly chemical drugs. Due to long-term clinical irrational drug use, drug resistance has increased year by year, and its curative effect has gradually decreased or even become invalid. Theref...

Claims

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Application Information

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IPC IPC(8): A61K36/736A61P31/04A61P1/12
Inventor 曹国文陈春林翟少钦郑华张素辉张邑帆
Owner CHONGQING ACAD OF ANIMAL SCI
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