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Platanus pollen allergen mixture

A technology of plane tree and allergen, applied in the direction of allergen antigen components, drug combination, respiratory system diseases, etc., can solve problems such as inaccurate diagnosis results and ineffective treatment effects

Inactive Publication Date: 2014-10-08
北京新华联协和药业有限责任公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Patient allergies caused by one-ball and three-ball Platanus pollen are sometimes overlooked, leading to inaccurate diagnosis and ineffective treatment of some patients with Platanus pollen allergy

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1 1

[0025] The preparation of embodiment 1 ball sycamore pollen raw material

[0026] 1) Collect a ball of Platanus flower buds in full bloom during the flowering and pollination season of Platanus plants, wash them with clean water for more than three times to remove impurities such as dust attached to the flower buds, dry the flower buds with a hair dryer, place the flower buds on clean kraft paper, and dry them in the air .

[0027] 2) The airing environment of flower buds requires sufficient sunlight and good ventilation. The pollen is collected by natural shedding method, and the collected pollen is passed through 400-mesh and 800-mesh sieves by ultrasonic vibrating sieve method, and the pollen between 400-mesh and 800-mesh sieves is taken.

[0028] 3) Degrease the pollen with acetone vibration at -40°C for more than 3 times, each time for 30 minutes, and vacuum-dry for more than 48 hours.

[0029] 4) The vacuum-dried pollen is filled, labeled, and filled with high-purity ni...

Embodiment 2 2

[0030] The preparation of embodiment 2 Platanus biscuits pollen raw material

[0031] 1) During the flowering and pollination season of Platanus plants, collect the flower buds of Platanus biscuits in full bloom, wash them with clean water for more than three times to remove impurities such as dust attached to the flower buds, dry the flower buds with a hair dryer, place the flower buds on clean kraft paper, and dry them in the air .

[0032] 2) The airing environment of flower buds requires sufficient sunlight and good ventilation. The pollen is collected by natural shedding method, and the collected pollen is passed through 400-mesh and 800-mesh sieves by ultrasonic vibrating sieve method, and the pollen between 400-mesh and 800-mesh sieves is taken.

[0033] 3) Degrease the pollen with acetone vibration at -40°C for more than 3 times, each time for 30 minutes, and vacuum-dry for more than 48 hours.

[0034] 4) The vacuum-dried pollen is filled, labeled, and filled with hig...

Embodiment 3 3

[0035] The preparation of embodiment 3 three-ball sycamore pollen raw materials

[0036] 1) During the flowering and pollination season of Platanus plants, collect the flower buds of the three-ball Platanus in full bloom, wash them with clean water for more than three times to remove impurities such as dust attached to the flower buds, dry the flower buds with a hair dryer, place the flower buds on clean kraft paper, and dry them in the air .

[0037] 2) The airing environment of flower buds requires sufficient sunlight and good ventilation. The pollen is collected by natural shedding method, and the collected pollen is passed through 400-mesh and 800-mesh sieves by ultrasonic vibrating sieve method, and the pollen between 400-mesh and 800-mesh sieves is taken.

[0038] 3) Degrease the pollen with acetone vibration at -40°C for more than 3 times, each time for 30 minutes, and vacuum-dry for more than 48 hours.

[0039] 4) The vacuum-dried pollen is filled, labeled, and filled...

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Abstract

The invention provides a platanus pollen allergen mixture and a preparation method thereof. The mixture is prepared by mixing three types of platanus pollen allergens and a pharmaceutically acceptable carrier, wherein the three sensitizing platanus plants are platanus occidentalis, platanus acerifolia and platanus orientalis. The platanus pollen allergen mixture comprises three main sensitizing platanus pollen allergens, and is more effective than a single platanus pollen allergen preparation.

Description

technical field [0001] The invention belongs to the field of biological technology, and in particular relates to an allergen for diagnosis and treatment of allergic rhinitis, asthma, allergic dermatitis and allergic asthma specific immunodiagnosis and treatment induced by Platanus pollen and a preparation method thereof. Background technique [0002] In 1911, scientists Noon and Freeman first used pollen extract to treat pollen allergy, and allergens have been developed since then. my country's allergens have been developed since 1956, and breakthroughs have been made. The main types of allergenic allergens in China have been discovered, and corresponding allergen products have been developed. Platanus pollen is an important spring allergenic pollen in China. [0003] Allergen-specific immunodiagnostic methods are divided into in vivo experiments and in vitro experiments. [0004] The methods of allergen-specific immunotherapy are mainly divided into subcutaneous injection...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K39/36A61P37/08A61P11/02A61P17/00A61P11/06
Inventor 郝廷牛占坡马博晨乔秉善王玉玲鲍亚丽马志刚
Owner 北京新华联协和药业有限责任公司
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