Mass spectrum ion source and mass spectrometer

Abstract

The invention provides a mass spectrum ion source and a mass spectrometer. The mass spectrum ion source includes a sampling device, a spray needle and a capillary pipe. The sampling device includes a T-junction, and a liquid sample inlet pipe, a liquid sample outlet pipe and a waste-liquid pipe, which are connected to the T-junction, and a constant-pressure valve installed at the waste-liquid pipe. The spray needle enables a liquid sample to become charged ions through an electrospray process. The capillary pipe guides the charged ions to a mass analyzer. When the quantity of the liquid sample which enters the T-junction via the liquid sample inlet pipe is overly large, the constant-pressure valve is started so that redundant liquid sample flows out from the waste-liquid pipe and thus the pressure and flow of the liquid sample outlet pipe are maintained at set values. In the mass spectrum ion source and mass spectrometer, the flow rate of only a specific quantity of liquid sample which enters the spray needle via the liquid sample outlet pipe is constant without changing with the flow rate of the injected sample. Therefore, the spray needle is kept at an optimal flow rate, an atomization effect is great and charged ions which are smaller in size can be formed without using an atomized gas or a blowback gas and thus the use cost of the mass spectrum ion source is low.

Description

technical field [0001] The invention relates to a mass spectrometer ion source and a mass spectrometer used in the field of analytical instruments. Background technique [0002] Chromatography-mass spectrometers are widely used in scientific research and biological detection and analysis, and their structures mainly include liquid chromatography and mass spectrometry. Among them, the liquid chromatograph is used to preliminarily process the liquid sample to be detected to form a relatively pure liquid sample. A mass spectrometer mainly includes a mass spectrometer ion source and a mass analyzer. The mass spectrometer ion source is divided into many different types. The electrospray ion source includes a charged spray needle, capillary and heating device for heating the capillary. The charged spray needle is set in the atmosphere and is used to receive liquid chromatography. The treated relatively pure liquid sample is ionized and vaporized to form gaseous charged ions; one...

AI Technical Summary

Problems solved by technology

[0005] The purpose of the present invention is to provide a mass spectrometer ion source and a mass spectrometer that can form smaller-sized charged ions without back blowing gas and atomizing gas, to solve the problems caused by the need for back blowing gas and atomizing gas in the above-mentioned prior art wasteful technical problems

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