Corn stigma anti-fatigue oral liquid and preparation method thereof

Abstract

The invention relates to corn stigma oral liquid with an anti-fatigue function, which is prepared by taking corn stigma, chrysanthemum and liquorice as raw materials, and subjecting the materials to extracting, filtering, mixing, sterilizing and filling. The corn stigma anti-fatigue oral liquid is administrated to mice in a high-dose group, a mediate-dose group, a low-dose group and a blank control group through gavage for 30 d, and the results show that by administrating the corn stigma oral liquid, the burden swimming time of the mice can be prolonged; the activity of lactic acid dehydrogenase is increased; the generation of urea nitrogen is reduced; and hepatic glycogen of the mice in different groups is improved to different extent. An acute toxicity test shows that LD 50 can not be detected, suggesting that the corn stigma oral liquid has no toxic or side effect. In a maximum dosing test, the mice are administrated with the corn stigma oral liquid in high, mediate and low doses three times a day, and the blank group is administrated with equal volume of saline through gavage. The mice are observed for 14 d after dosing, death does not occur, piloerection, moving restlessly, tail erecting, excited jumping, curling up, hyperactivity, slow response to stimulation or allergy does not occur, and symptoms such as stiffness, fremitus, ataxia do not occur either, suggesting that the maximum dose of the corn stigma oral liquid for the mice is 60 g / kg.

Description

technical field [0001] The invention belongs to the field of health care products (traditional Chinese medicine preparations), and in particular relates to a corn silk anti-fatigue oral liquid and a preparation method thereof. Background technique [0002] Corn silk is the style and stigma of the grass plant Zea genus. It is rich in nutrients, not only polysaccharides, flavonoids, saponins and other substances, but also contains fatty oils, sitosterol, alkaloids, V K , malic acid, amino acids, etc. It is one of the commonly used medicinal materials included in the 1985 edition of the Pharmacopoeia of the People's Republic of China (Part One), and is a traditional Chinese medicinal material in my country. Corn silk is sweet, light, and flat in nature, and can be used to treat nephritis, gallstones, and diabetes. Modern pharmacological studies have confirmed that corn must have the effects of lowering blood sugar, anti-cancer, antibacterial, enhancing immune function, diuresis...

AI Technical Summary

Problems solved by technology

[0005] In this paper, using corn silk juice, chrysanthemum juice, licorice juice, sucralose and potassium sorbate as raw materials, on the basis of base materials, the production process of corn silk chrysanthemum licorice oral liquid is determined through orthogonal experiments, which can not only meet the requirements of health food Nutritional requirements, and has good taste, flavor and color, there is no report about corn silk anti-fatigue oral liquid and its preparation method, this patent has certain significance for meeting the needs of the health food market

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