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External patch with muscle and bone soothing effect and preparation method of external patch

The technology of Jingutong and patch is applied to the field of Jingutong external patch and its preparation, which can solve the problems of inability to determine the monarch, minister, assistant and envoy of the drug, the main role of the drug, the mutual influence of the drug, etc., and achieves superior geographical conditions and high content of active ingredients of medicinal materials. , the effect of fewer types of medicinal herbs

Active Publication Date: 2014-12-10
GUIZHOU ZHIGANG MIAO MINORITY PRESCRIPTION PHA CO LTD CHINA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, there are more and more researches on the treatment of joint diseases, such as patent CN200710173341.6, which is named as medicine for the treatment of osteoarthritis and its preparation method, which discloses 29 Chinese herbal medicines composed of Clematis clematis, Rhizoma Chuanxiong, Salvia miltiorrhiza, Shenjincao, Daxueteng, etc. The topical ointment made of a variety of Chinese herbal medicines uses a wide variety of Chinese herbal medicines, and there is no significant difference in the dosage of each herbal medicine, so it is impossible to determine the compatibility of the medicines, and it is also impossible to determine which medicine plays the main role. If there are too many, it will also cause the increase of impurities, drug interaction, etc.; another example is the patent application CN201310204439.1, the Chinese medicine preparation for the treatment of human cervical spine, lumbar protrusion and hyperplasia, which discloses a total of 85 Chinese herbal medicines composed of Daxueteng, Chuanxiong, Achyranthes bidentata, and Shenjincao products made from a variety of medicinal materials; there is also patent CN200810047135.8, Gubi syndrome plaster with expelling wind and dampness, promoting blood circulation and removing blood stasis, dredging collaterals and relieving pain and its preparation method, which discloses a combination of Rhizoma Chuanxiong, Fangji, Frankincense, Cortex Phellodendri, Notopterygium, Huai Ointment made of 19 kinds of medicinal materials such as Achyranthes bidentata
The above-mentioned drugs have all played a certain therapeutic effect, but there are also defects such as heavy weight, difficulty in determining the main drug, and drug interaction.
In addition, there are many types of health care products on the market for the treatment of joint diseases, but most of them are rubber ointments, mainly Western medicines or chemical accelerators such as borneol, menthol, or pungent and cool Chinese medicines, which contain less medicine and are easy to spread and fail.

Method used

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  • External patch with muscle and bone soothing effect and preparation method of external patch
  • External patch with muscle and bone soothing effect and preparation method of external patch
  • External patch with muscle and bone soothing effect and preparation method of external patch

Examples

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Effect test

Embodiment 1

[0029] Backing layer: non-woven fabric; Protective layer: polyester film;

[0030] The composition of the paste containing medicine: 400g of traditional Chinese medicine extract, 900g of micro-powder silica gel, 1500g of calcium carbonate, 1000g of glycerin, 500g of sodium alginate, 700g of gelatin, 100g of titanium dioxide;

[0031] Preparation method: (1) Preparation of traditional Chinese medicine extract: remove impurities from S. chinensis, Chuanxiong, Achyranthes bidentata and Shenjincao respectively, and then pulverize them into coarse powder, pass through a 40-mesh sieve, and take 500 g of the above-mentioned S. chinensis, Ligusticum chuanxiong 300g, 200g of Achyranthes bidentata and 400g of Achyranthes chinensis, impregnated with 6 times of 50% ethanol for 3 times, each time for 4 days, combined the impregnated liquid, filtered, and the filtrate was concentrated to an extract with a relative density of 1.20 at 60°C, and added 100g of borneol passed through a 80-mesh s...

Embodiment 2

[0036] Backing layer: non-woven fabric; protective layer: polyethylene film;

[0037] Composition of medicinal paste: 200g of traditional Chinese medicine extract, 1200g of micro-powder silica gel, 1000g of calcium carbonate, 1500g of glycerin, 200g of sodium alginate, 1000g of gelatin, 50g of titanium dioxide;

[0038] Preparation method: (1) Preparation of traditional Chinese medicine extract: remove impurities from S. chinensis, Chuanxiong, Achyranthes bidentata and Shenjincao respectively, and then pulverize them into coarse powder, pass through a 40-mesh sieve, and take 200 g of the above-mentioned S. 100g, 100g of Achyranthes bidentata and 100g of Achyranthes chinensis, impregnate twice with 5 times of 60% ethanol respectively, each time for 4 days, combine the impregnating liquid, filter, and concentrate the filtrate to an extract with a relative density of 1.15 at 60°C, add 50g of borneol passed through a 60-mesh sieve, mixed evenly;

[0039] (2) Preparation of matrix...

Embodiment 3

[0043] Backing layer: rayon; Protective layer: release paper;

[0044] The composition of the medicinal paste: 600g of Chinese medicine extract, 600g of micro-powdered silica gel, 2000g of calcium carbonate, 500g of glycerin, 800g of sodium alginate, 400g of gelatin, and 200g of titanium dioxide;

[0045] Preparation method: (1) Preparation of traditional Chinese medicine extract: remove impurities from S. chinensis, Chuanxiong, Achyranthes bidentata and Shenjincao respectively, then pulverize them into coarse powder, pass through a 40-mesh sieve, and take 800 g of the above-mentioned S. 500g, 300g of Achyranthes bidentata and 700g of Achyranthes chinensis, impregnated 4 times with 8 times of 40% ethanol respectively, each time for 4 days, combined the impregnated liquid, filtered, the filtrate was concentrated into an extract with a relative density of 1.20 at 60°C, and added 200g of borneol passed through an 80-mesh sieve, mixed evenly;

[0046] (2) Preparation of matrix: m...

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Abstract

The invention discloses an external patch with a muscle and bone soothing effect as well as a preparation method and application of the external patch. The external patch with the muscle and bone soothing effect is provided with a backing layer, an ointment-containing body and a protective layer, wherein the ointment-containing body is prepared by mixing a traditional Chinese medicine extract, a matrix and a crosslinking agent, and the traditional Chinese medicine extract is prepared from the following raw materials in parts by weight: 200-800 parts of sargentodoxa cuneata, 100-500 parts of ligusticum chuanxiong, 100-300 parts of achyranthes bidentata, 100-700 parts of lycopodii herbs and 50-200 parts of borneol. The invention also provides the preparation method of the external traditional Chinese medicine patch. The patch has the health-care effects of promoting blood circulation to remove meridian obstruction, eliminating cold to stop pain, promoting the rehabilitation of bone and joint parts, relieving pain and discomfort at parts such as necks, shoulders, waists and knees and promoting the rehabilitation of the parts. Compared with the prior art, the external patch is safe in use, exact in curative effect and simple in prescription; and the preparation method is simple in process and suitable for large-scale industrial production.

Description

technical field [0001] The invention relates to a traditional Chinese medicine patch for activating blood circulation and dredging collaterals, dispelling stagnation and reducing swelling, in particular to a Jingutong external patch and its preparation method and application. technical background [0002] Arthralgia, limb numbness, paresthesia, etc. are common syndromes in limbs and bone joints, mostly caused by rheumatism and cold pathogens, hyperosteogeny, bone and joint degeneration, etc. Although there are many different causes, the symptoms are generally similar. Clinical data show that the incidence rate in my country is as high as about 20%, especially among middle-aged and elderly people over 40 years old, the incidence rate can reach 42%. The incidence rate is higher among people who work underground for many years, stand for a long time, work and live in the field and in severe cold and humid areas. Once the disease occurs, it is painful and seriously affects the...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/236A61K9/70A61P29/00
Inventor 李志刚李华萍
Owner GUIZHOU ZHIGANG MIAO MINORITY PRESCRIPTION PHA CO LTD CHINA
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