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Specimen collector for collecting a laser micro-dissectate

A sample collection, laser technology, used in laboratory containers, test sample preparation, instrumentation, etc., to solve problems such as low cutting quality, improve work comfort, reduce contamination and/or material loss, The effect of reducing working hours

Active Publication Date: 2015-01-28
LEICA MICROSYSTEMS CMS GMBH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] The aim of DE 103 29 674 A1 is to overcome disadvantages of UV ablation, such as absorption of UV rays in biological tissue or lower cutting quality

Method used

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  • Specimen collector for collecting a laser micro-dissectate
  • Specimen collector for collecting a laser micro-dissectate
  • Specimen collector for collecting a laser micro-dissectate

Examples

Experimental program
Comparison scheme
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Embodiment Construction

[0049] figure 1 Five steps of the method are shown, in which an exemplary embodiment of the sample collector 1 according to the invention is used.

[0050] The sample collector 1 comprises a collection chamber 10 which, in the case shown, has two valves 101 and 102 . In the closed state, the first valve 102 forms a blockage (bottom) of the collection chamber 10 away from the sample 106 . In a first illustrated step S11 the second valve 101 (lid) is opened, so that the collection point is already used to receive the falling sectioning objects 111 . On its bottom side, downstream of the first valve 102 , the collection chamber 10 is connected to a capillary line, which serves as an outlet for transporting the sectioned material from the collection area. The continued conduction of the sectioned material from the collection area of ​​the collection chamber 10 to the discharge pipe is monitored via the valve 102 . In the illustrated step S11 the valve 102 is closed.

[0051] T...

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PUM

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Abstract

The present invention relates to a laser micro-dissectate specimen collector (1) for a laser micro-dissection device, wherein the specimen collector comprises an inspectable collecting chamber (10) for receiving a dissectate (111), wherein the collecting chamber (10) has, on the specimen side, an opening which is open to the environment and which is used to receive the dissectate (111), the collecting chamber (10) has a first valve (102, 122) which, in the closed state, forms a closure of the collecting chamber (10) directed away from the specimen and used to retain the dissectate (111), and wherein a capillary line (107) is arranged downstream of the first valve (102, 122) and is connected to the collecting chamber (10) in order to transport the dissectate (111) out of said collecting chamber (10).

Description

technical field [0001] The present invention relates to a laser microsection sample collector for a laser microsection device and a laser microsection device of this type. Background technique [0002] In laser microdissection, selected areas of tissue or cells are separated or excised ("sectioned") from the microscopic tissue sample by means of focused laser beams for further analysis. [0003] DE 100 18 253 C2, DE 10 2005 028 062 B4 and DE 10 2005 008 925 A1 of the applicant describe possible methods and systems for laser microdissection using a microscope. [0004] Capillary-based analyzers have been developed to transport, sort, analyze individual cells or even chromosomes dissociated from tissues in small droplets or solutions through capillary systems, and continue to use them after analysis. Capillary-based analytical techniques are used and promoted, for example, by the companies Fluidigm (http: / / www.fluidgim.com) and RainDance Technologies (http: / / www.raindancetech...

Claims

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Application Information

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IPC IPC(8): G01N1/04G01N1/28
CPCB01L3/502738B01L2300/0816G01N1/286B01L3/502715B01L2300/0681B01L2400/0406G01N2001/2886B01L3/502784B01L2200/0631B01L2200/0673B01L2200/10B01L2300/0864
Inventor F·施劳德拉夫
Owner LEICA MICROSYSTEMS CMS GMBH