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Application of traditional Chinese medicine composition to prepare medicines treating colorectal cancer

A composition and technology for colorectal cancer, which can be used in drug combinations, medical raw materials derived from arthropods, anti-tumor drugs, etc., can solve the problems of high economic cost, hidden lesions, and unoptimistic treatment prospects, and achieve reasonable compatibility and adverse reactions. small effect

Inactive Publication Date: 2015-02-04
HEBEI YILING MEDICINE INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

And due to factors such as hidden lesions and unobvious symptoms, more than half of the patients were in the middle and late stage when they went to the doctor, and lost the chance of radical treatment.
Existing treatments, including emerging molecular targeted therapy and chemotherapy, still lack obvious, definite and lasting curative effect on advanced colorectal cancer
And at the cost of high economic costs and reduced quality of life for patients, the prospects for treatment are not optimistic

Method used

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  • Application of traditional Chinese medicine composition to prepare medicines treating colorectal cancer
  • Application of traditional Chinese medicine composition to prepare medicines treating colorectal cancer
  • Application of traditional Chinese medicine composition to prepare medicines treating colorectal cancer

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0072] Party:

[0073] Astragalus 145g Ligustrum lucidum 250g Ginseng 50g Ganoderma lucidum 85g Curcuma 85g Atractylodes 80g

[0074] Scutellaria barbata 90 g Gynostemma 300 g Poria cocos 60 g Gallus chinensis 35 g Snakeberry 85 g

[0075] Baiying 145 g, capillary 95 g, Xu Changqing 175 g, wood beetle 15 g, Hedyotis diffusa 145 g.

[0076] Preparation:

[0077] (1), take the Chinese medicinal material according to the weight ratio of the crude drug, and select it;

[0078] (2) For ginseng and Ligustrum lucidum, add 8 times the amount of 70% ethanol to reflux extraction twice, the first time for 3 hours, and the second time for 2 hours, combine the extracts, recover the ethanol until there is no alcohol smell, ginseng and Ligustrum lucidum Residue for use;

[0079] (3) For Curcuma, Atractylodes Rhizoma, and Xu Changqing, add 6 times the amount of water to extract the volatile oil. The oil extraction time is not less than 8 hours. The volatile oil is collected in anothe...

Embodiment 2

[0085] Party:

[0086] Astragalus 250 g Ligustrum lucidum 160 g Ginseng 80 g Ganoderma lucidum 50 g Curcuma 160 g Atractylodes macrocephala 50 g

[0087] Scutellaria barbata 180 g Gynostemma 200 g Poria cocos 80 g Gallinarum 25 g Snakeberry 175 g

[0088] Baiying 85 g, capillary 165 g, Xu Changqing 95 g, wood beetle 20 g, Hedyotis diffusa 95 g.

[0089] Preparation:

[0090] (1), take the Chinese medicinal material according to the weight ratio of the crude drug, and select it;

[0091] (2) Ligustrum lucidum and ginseng were extracted once with 6 times the amount of 50% ethanol, extracted for 1 hour, the extract was filtered, and the ethanol was recovered from the filtrate until it had no alcohol smell, and the dregs were used for later use;

[0092] (3) Add 4 times the amount of water to extract the volatile oil from Curcuma, Atractylodes Rhizoma, and Xu Changqing, collect the volatile oil, collect it in another device, and reserve the residue and aqueous solution for l...

Embodiment 3

[0097] Party:

[0098] Astragalus 200 g Ligustrum lucidum 200 g Ginseng 65 g Ganoderma lucidum 65 g Curcuma 132 g Atractylodes macrocephala 64 g

[0099] Scutellaria barbata 128 g Gynostemma 256 g Poria cocos 65 g Gallus chinensis 30 g Snakeberry 128 g

[0100] Baiying 128 g, capillary wormwood 128 g, Xu Changqing 128 g, Hedyotis diffusa 128 g, ground beetle 20 g.

[0101] Preparation:

[0102] (1), take the Chinese medicinal material according to the weight ratio of the crude drug, and select it;

[0103] (2), Ligustrum lucidum, ginseng 10 times the amount of 90% ethanol extraction 3 times, each 4 hours, combined extracts, filtered, the filtrate reclaims ethanol until it has no alcohol smell, and the dregs are for subsequent use;

[0104] (3) Add 8 times the amount of water to extract the volatile oil from Curcuma, Atractylodes Rhizoma, and Xu Changqing, collect the volatile oil, collect it in another device, and reserve the residue and aqueous solution for later use; ...

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Abstract

The invention discloses application of a traditional Chinese medicine composition to prepare medicines treating colorectal cancer, and belongs to the field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from radix astragali, fructus ligustri lucidi, ginseng, ganoderma, rhizoma curcumae, rhizoma atractylodis macrocephalae, herba scutellariae barbatae and bulk drugs, and is good in colorectal cancer treatment effect and free of obvious side effect.

Description

technical field [0001] The invention belongs to the field of application of traditional Chinese medicines, and in particular relates to the application of traditional Chinese medicine compositions in treating cancer. Background technique [0002] Colorectal cancer (also known as colon cancer) is a common malignant tumor of the digestive tract that can occur in any part of the colon. Colorectal cancer is the most common digestive system malignancy. Its incidence rate is increasing year by year, and it ranks the third among malignant tumors in the world. In North America and Western Europe, the incidence rate is relatively high. In the United States, colon cancer accounts for the second cause of all cancer deaths. In China, it ranks fourth, and its incidence increases with age, starting from the age of 40 and peaking at the age of 60 to 75. Colorectal cancer has obvious geographical distribution, and family genetic factors have also been reported. Clinical manifestations: 1...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P35/00A61K35/57A61K35/64
CPCA61K36/9066A61K9/16A61K9/20A61K35/57A61K35/63A61K36/074A61K36/076A61K36/258A61K36/27A61K36/28A61K36/284A61K36/424A61K36/481A61K36/539A61K36/638A61K36/73A61K36/748A61K36/81A61K2236/331A61K2236/333A61K2236/39A61K2300/00
Inventor 周梦夏秦拢王猛王永
Owner HEBEI YILING MEDICINE INST
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