A kind of medicament for treating amiodarone-induced phlebitis for external use and preparation method thereof

Abstract

The invention discloses an externally-applied medicament for treating phlebitis caused by amiodarone and a preparation method thereof. The medicament is prepared from Chinese water chestnut, pentoxifylline and preservatives, wherein the medicament comprises the following components in percentage by mass: 98.5-99.7% of peeled Chinese water chestnut, 0.2-1.0% of pentoxifylline and 0.1-0.5% of the preservatives. The medicament disclosed by the invention is simple in preparation process, wide in raw material source, cheap in price and high in efficiency; when the medicament is externally applied, patients can consciously feel comfortable; and the medicament is an effective medicament for treating phlebitis caused by amiodarone.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a medicine for treating phlebitis, in particular to a medicine for externally treating phlebitis caused by amiodarone and a preparation method thereof. Background technique [0002] Phlebitis is one of the most common complications of intravenous fluid therapy. It is caused by the chemical inflammatory reaction of the local vein wall due to the high input concentration, strong irritating drugs or too long time of placing irritating plastic tubes in the vein, or it can also be caused by repeated punctures of the same vein Intravenous infection. The normal pH value of blood is 7.35-7.45. The medicine solution injected beyond this range, whether it is too acidic or too alkaline, can interfere with the normal metabolism and function of the vascular intima and cause phlebitis. [0003] Amiodarone Hydrochloride Injection is a benzopyrene furan derivative, which belongs t...

AI Technical Summary

Problems solved by technology

[0004] The pain of phlebitis caused by amiodarone intravenous injection is different from that of ordinary phlebitis. The pain symptoms are mainly due to the burning pain caused by the acidic substances in the drug stimulating the local vascular endothelium, and even nodular induration of the skin around the blood vessels, local Tissue necrosis brings great pain to patients, affects the treatment effect, and also brings inconvenience to nursing work

Traditional treatment commonly used 50% magnesium sulfate or 33% magnesium sulfate wet compress, using its hyperosmotic effect to promote the subsidence of inflammation and edema in local tissues to achieve the purpose of pain relief, but the effect is slow, the curative effect is poor, and it is easy to cause skin dryness and discomfort, and the patient feels comfortable. Difference

In addition, some medicines such as Hirudoid Ointment and Ruyi Jinhuang Powder can effectively treat phlebitis, but these methods are not very effective in quickly relieving pain.

At present, new dressings are also used in the treatment of phlebitis, such as Kanghuier Transparent Plaster, Anpu Plaster, etc., whose mechanism of action is to eliminate inflammation, relieve pain, prevent necrosis, etc., but because of its high price, its application range in primary hospitals is limited

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