Normal-temperature perfusion system for storing human organs

Abstract

The invention discloses a normal-temperature perfusion system, in particular discloses a normal-temperature perfusion system for storing human kidneys, and belongs to the technical field of designing and manufacturing medical instruments. The invention provides a normal-temperature perfusion system for storing human organs, which can obviously reduce functional lesions to a stored kidney during storage of transplanted organs. The normal-temperature perfusion system comprises a perfusion pump, a human organ storage device and a perfusion liquid monitoring component, wherein a perfusion liquid input end and a perfusion liquid output end of the perfusion pump are penetrated into the human organ storage device and then are communicated with a perfusion body fluid output end and a perfusion body fluid output end of a human organ needed to be stored respectively; the perfusion liquid monitoring component is connected with the perfusion liquid output end of the perfusion pump in series; the human organ storage device also comprises a temperature adjusting mechanism; and the ambient temperature of the human organ storage device is adjusted and controlled by the temperature adjusting mechanism.

Description

technical field [0001] The invention relates to a normal temperature perfusion system, in particular to a normal temperature perfusion system for preserving human organs, and belongs to the technical field of medical device design and manufacture. Background technique [0002] The shortage of donor resources is the most important obstacle restricting organ transplantation, so it is urgent to expand the source of organs. Donated organs after death mainly include the kidneys and livers of the deceased. At present, there are mainly two types of organ donation after death: the first is DCD, which is heart death donation; the second is DBD, which is brain death donation. Compared with DBD donors, DCD donors experienced longer warm ischemia time, 2.5-4 times higher incidence of postoperative delayed functional recovery (DGF), higher proportion of primary non-function (PNF), and relatively poor long-term survival. This led to the reluctance of transplant physicians to use DCD don...

AI Technical Summary

Problems solved by technology

As a result, these two preservation methods have two unavoidable huge defects: the first is the damage of the cold storage itself to the organs; the second is the ischemia-reperfusion injury

These injuries may aggravate the functional damage of DCD donors, resulting in the loss of organs, and further straining the scarce organ resources

It also increases the risk of organ transplantation

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