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A functional dressing for inhibiting scar hyperplasia and preparation method thereof

A functional and scar technology, applied in the medical field, can solve the problems of inability to meet complex wound care requirements and single function, and achieve the effect of inhibiting scar proliferation and reducing pain.

Inactive Publication Date: 2017-02-08
GUANGDONG TAIBAO MEDICAL SCI TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, because the functions of these two types of dressings are relatively single, they cannot meet the nursing requirements of various complex wounds. Even the same wound has different dressing performance requirements at different healing stages, resulting in frequent dressing changes, which has brought great pain to patients for a long time. suffering, and thus its limitations are becoming increasingly prominent

Method used

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  • A functional dressing for inhibiting scar hyperplasia and preparation method thereof
  • A functional dressing for inhibiting scar hyperplasia and preparation method thereof
  • A functional dressing for inhibiting scar hyperplasia and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Add 10g of chitosan and 20g of fucoidan to a mortar and grind them in a certain proportion, and stir them mechanically for 3 minutes to form a powder mixture; add the above powder mixture to 50mL of methyl silicone oil with a molecular weight of about 8000, and add 20g polyvinyl alcohol and carboxymethyl cellulose of equal mass form a mixed solution; add 0.1g sodium dodecylbenzene sulfonate to the above mixed solution, and stir it with a mechanical stirrer at a high speed at 40°C to make it evenly mixed to obtain a composite silicon gel Glue; the composite silicone gel is cast into a film, soaked in 75% alcohol disinfectant after the film is formed, washed with distilled water at the same time, and then drilled with a needle with a diameter of 0.5mm on the surface of the film to penetrate 300 pieces / cm 2 small holes; the activated carbon fiber is pasted on one side of the composite silicone gel and fixed on the pressure-sensitive non-woven fabric at the same time, and th...

Embodiment 2

[0028] Add 15g of chitosan and 30g of fucoidan into a mortar and grind them in a certain proportion, and stir them mechanically for 5 minutes to form a powder mixture; add the above powder mixture to 45mL of methyl vinyl cyclosiloxane with a molecular weight of about 15,000 and add 10g carboxyethyl cellulose to form a mixed solution; add 0.05g hexadecyltrimethylammonium bromide to the above mixed solution, and stir it with a mechanical stirrer at a high speed at 60°C to make it evenly mixed to obtain a composite silicon gel Glue; the composite silicone gel is cast into a film, soaked in 75% alcohol disinfectant after the film is formed, and washed with distilled water at the same time, and then drilled on the surface of the film with a needle with a diameter of 0.9mm. 150 / cm 2 small holes; the activated carbon fiber is pasted on one side of the composite silicone gel, and fixed on the pressure-sensitive adhesive non-woven fabric at the same time, and the other side is covered w...

Embodiment 3

[0036]Put 8g of chitosan and 16g of fucoidan in a certain proportion and grind them in a mortar, stir them mechanically for 1min to form a powder mixture; add the above powder mixture to 60mL of phenyl silicone oil with a molecular weight of about 20000, and add 16g Carboxymethyl cellulose forms a mixed solution; add 0.08g Tween-80 to the above mixed solution, stir it with a mechanical stirrer at a high speed at 50°C to mix evenly, and obtain a composite silicone gel; cast the composite silicone gel into a film , After the film is formed, soak it in 75% alcohol disinfectant, wash it with distilled water, and then use a needle with a diameter of 0.7mm to drill 200 holes / cm on the surface of the film. 2 small holes; the activated carbon fiber is pasted on one side of the composite silicone gel, and fixed on the pressure-sensitive adhesive non-woven fabric at the same time, and the other side is covered with a peeling layer, and the product is obtained after packaging and irradiat...

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Abstract

The invention relates to a functional dressing for inhibiting scar hyperplasia and a preparation method thereof. The dressing comprises a fixed layer, an activated carbon fiber, a composite silica gel and a stripping layer, wherein the composite silica gel comprises the following components: chitosan, fucoidin, silicone, gels and surfactants; and the activated carbon fiber is arranged on the fixed layer, and the composite silica gel is arranged on the activated carbon fiber. The silica gel functional dressing disclosed by the invention can play roles in resisting bacteria and diminishing inflammation, stopping bleeding and relieving pain, adsorbing seepage and the like in the beginning of wound formation; and meanwhile, by adopting the silica gel functional dressing, a warm and humid environment beneficial to wound healing can also be formed, the wound healing can be accelerated, fibrous tissue proliferation can also be inhibited in a wound healing process, and the generation of scars can be resisted from the source.

Description

technical field [0001] The invention relates to the field of medical technology, in particular to a functional dressing for inhibiting scar hyperplasia and a preparation method thereof. Background technique [0002] A wound is a breach of the integrity and continuity of the human skin. In daily life, there are many types of wounds, including cuts caused by mechanical factors, burns caused by factors such as electricity, heat, and chemicals, and chronic wounds caused by the patient's physiological morbidity. Various wounds on the surface of the human body are unavoidable and common symptoms in life. The longer the wound healing is delayed, the less likely the scars will disappear after healing. The rapid growth and repair of the surface epithelium is more needed. Therefore, the ideal therapeutic index for all kinds of skin wounds is to control secondary infection and promote rapid wound healing. [0003] In the past, for the care of wounds, one was mainly selected from cot...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L15/44A61L15/28A61F13/02
Inventor 卢亢陈泽楚熊亮陈锦涛
Owner GUANGDONG TAIBAO MEDICAL SCI TECH
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