A kind of porous polyurethane film with gradient pore structure for artificial skin and its preparation method

A polyurethane film, gradient hole technology, applied in medical science, prosthesis and other directions, can solve the problems of difficulty in resisting the invasion of external bacteria, the upper layer of silicone rubber has too large pore size, and cannot be used for a long time, so as to keep the wound moist, excellent mechanical properties, The effect of good water permeability
CN104524640BActive Publication Date: 2016-06-29SICHUAN UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
SICHUAN UNIV
Publication Date
2016-06-29

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Abstract

The invention discloses a preparation method of a porous polyurethane film with a gradient porous structure. The preparation method is characterized by comprising the following steps: adding polyurethane into a solvent for dissolving, adding a pore-foaming agent, and mechanically stirring for a period of time to obtain suspension; defoaming the suspension in vacuum, carrying out film casting on a mold, carrying out curing film formation in absolute ethyl alcohol coagulation bath, soaking the film in deionized water to dissolve the pore-foaming agent and completely remove the pore-foaming agent; taking out the film, drying the film in a blast oven to obtain the porous polyurethane film with the gradient porous structure, the upper and lower surfaces of the porous polyurethane film are trim and not curled, and the hand feeling is good. The film can be used as artificial skin and has the advantages of good water and air permeability, high water absorption, excellent mechanical properties, good biological affinity, etc.
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Description

[0001] technology field,

[0002] The invention relates to a porous polyurethane film with a gradient pore structure for artificial skin and a preparation method thereof, belonging to the technical field of bioengineering materials. Background technique

[0003] The skin is the largest organ of the human body and a natural barrier to protect the human body. It plays the role of perception, temperature regulation, secretion, excretion and absorption to the human body, and it is the first line of defense of the human immune system. When the skin is severely traumatized or burned, it may lead to a series of serious problems such as water and electrolyte imbalance, shock, and infection. At this time, autologous skin is urgently needed to cover the wounded surface. However, the source of autologous skin is limited, so it is particularly important to temporarily replace the dermis with an artificial skin that has a certain mechanical strength, toughness, waterproof and breathable, ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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