Liquid dressing and preparation method thereof

A technology of liquid dressing and liquid matrix, which is applied in medical science, bandages, absorbent pads, etc., can solve the problems of accelerating wound healing, and achieve the effect of accelerating wound healing, smooth and smooth film formation, and good disinfection and sterilization

Active Publication Date: 2015-04-29
GUANGZHOU SALIAI STEMCELL SCI & TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Since the essence of growth factors is protein, and the existing research results show that proteins will have an adverse effect on the film formation of liquid dressings, so there is n...

Method used

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  • Liquid dressing and preparation method thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0050] The preparation of embodiment 1 liquid dressing

[0051] The content of each component in the liquid matrix:

[0052] Polyvinyl alcohol: 9g, gum rosin: 5.5g, absolute ethanol: 75mL,

[0053] Gum turpentine: 15mL, Menthol: 3g, Water: 10mL.

[0054] The content of each component in the powder:

[0055] EGF 30 μg, bFGF 3000 U, hSCGF 55 ng and mannitol 2 μg.

[0056] Wherein, the preparation method of liquid matrix is:

[0057] (1) Heat the purified water to 90°C, keep it warm for 30 minutes, then cool down to 40°C;

[0058] (2) adding polyvinyl alcohol to the warm water obtained in step (1), swelling and dissolving;

[0059] (3) Gum rosin, gum turpentine, and menthol are respectively added in ethanol successively, stirred and dissolved, and set aside;

[0060] Add the mixed solution obtained in step (3) into the polyvinyl alcohol solution in step (2), stir to dissolve, and mix evenly to obtain a liquid matrix.

[0061] The preparation method of powder is:

[0062] ...

Embodiment 2

[0064] The preparation of embodiment 2 liquid dressings

[0065] The content of each component in the liquid matrix:

[0066] Polyvinyl alcohol: 8g, gum rosin: 50g, absolute ethanol: 75mL,

[0067] Gum turpentine: 13mL, Menthol: 2.5g, Water: 12mL.

[0068] The content of each component in the powder:

[0069] hSCGF 55ng and mannitol 3μg.

[0070] Wherein, the preparation method of liquid matrix is:

[0071] (1) Heat the purified water to 90°C, keep it warm for 30 minutes, then cool down to 40°C;

[0072] (2) adding polyvinyl alcohol to the warm water obtained in step (1), swelling and dissolving;

[0073] (3) Gum rosin, gum turpentine, and menthol are respectively added in ethanol successively, stirred and dissolved, and set aside;

[0074] Add the mixed solution obtained in step (3) into the polyvinyl alcohol solution in step (2), stir to dissolve, and mix evenly to obtain a liquid matrix.

[0075] The preparation method of powder is:

[0076] Dissolve hSCGF growth fa...

Embodiment 3

[0078] The preparation of embodiment 3 liquid dressings

[0079] The content of each component in the liquid matrix:

[0080] Polyvinyl alcohol: 5g, gum rosin: 3g, absolute ethanol: 75mL,

[0081] Gum turpentine: 10mL, Menthol: 10g, Water: 15mL.

[0082] The content of each component in the powder:

[0083] EGF 30 μg and mannitol 2 μg.

[0084] Wherein, the preparation method of liquid matrix is:

[0085] (1) Heat the purified water to 90°C, keep it warm for 30 minutes, then cool down to 40°C;

[0086] (2) adding polyvinyl alcohol to the warm water obtained in step (1), swelling and dissolving;

[0087] (3) Gum rosin, gum turpentine, and menthol are respectively added in ethanol successively, stirred and dissolved, and set aside;

[0088] Add the mixed solution obtained in step (3) into the polyvinyl alcohol solution in step (2), stir to dissolve, and mix evenly to obtain a liquid matrix.

[0089] The preparation method of powder is:

[0090] Dissolve the freeze-dried ...

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Abstract

The invention relates to the field of medical instruments, and particularly relates to a liquid dressing and a preparation method thereof. The liquid dressing comprises a liquid matrix and powder; the liquid matrix comprises a film forming agent, a disinfecting agent, a thickener, a hemostatic and water; powder comprises a growth factor and a vehicle. The liquid dressing comprises a liquid matrix and powder which are separately packed, wherein the power consists of the growth factor which can speed up the wound healing without escharosis. Proved by experiments, by using the liquid dressing containing the growth factor, the wound healing speed can be markedly increased, and the reparative regeneration time of the skin is shortened to 2-3 days.

Description

technical field [0001] The invention relates to the field of medical devices, in particular to a liquid dressing and a preparation method thereof. Background technique [0002] Dressings are medical devices that are placed over skin lesions to temporarily function as a skin barrier until the permanent skin barrier is rebuilt. Traditionally, a dry environment reduces the chance of infection. Therefore, a dry environment should be created for the wound as much as possible to facilitate wound healing. Therefore, traditionally the most used dressings are gauze and non-woven fabrics. The dressing has good air permeability, can fully keep the wound dry, and has the advantages of protecting the wound surface, simple application, and cheap price. But its shortcomings are also very prominent: (1) the barrier effect is poor; (2) the granulation tissue on the wound surface is easy to grow into the mesh of the gauze, which will damage the new tissue and cause pain when changing the d...

Claims

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Application Information

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IPC IPC(8): A61L15/26A61L15/34A61L15/44A61L15/46A61L15/42
Inventor 王一飞陈海佳葛啸虎舒辉萍马岩岩冯海燕
Owner GUANGZHOU SALIAI STEMCELL SCI & TECH CO LTD
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