Device for receiving and sampling radioactive drugs

Abstract

The invention provides a device for receiving and sampling radioactive drugs. The device comprises a synthesizer (1), a pipeline A (2), a sterile filtration membrane A (3), a three-way valve A (4), a sampling syringe (5), a product receiving bottle (6), a pipeline B (7), a sterile filtration membrane B (8) and a three-way valve B (9), and is characterized in that the pipeline A (2) is connected to the synthesizer (1), the three-way valve A (4) is arranged on the pipeline A (2) and is connected with the sampling syringe (5), the other end of the pipeline A (2) is arranged in the product receiving bottle (6), the pipeline B (7) is also arranged in the product receiving bottle (6), the sterile filtration membrane B (8) and the three-way valve B (9) are connected to the pipeline B (7), and the three-way valve B (9) is positioned at the right end of the sterile filtration membrane B (8). By using the device disclosed by the invention, the operations of operators during production can be reduced, the radiation risk is reduced, and the contamination risks in product receiving and sampling processes are reduced.

Description

technical field [0001] The invention relates to the field of radioactive isotope label synthesis, in particular, a radiopharmaceutical receiving and sampling device is designed. Background technique [0002] Radiopharmaceuticals are injected into the human body, so sterility testing must be carried out. The commonly used sampling method is to connect a sterile air filter membrane and a sampling syringe to the product receiving bottle, and sample the product through the syringe. Therefore, the traditional method There are the following 4 disadvantages: [0003] 1. The radiation measurement of the receiving bottle of radiopharmaceuticals is relatively large, and the risk to the operator will be relatively high. [0004] 2. The longer operation time means that the radiation time of the operator is longer, and the risk is also greater. [0005] 3. The operation time is long, which is not conducive to the quality of the product; for example, the product 18F-FDG has a half-life ...

AI Technical Summary

Problems solved by technology

[0003] 1. The radiation measurement of the receiving bottle of radiopharmaceuticals is relatively large, and the risk to the operator will be relatively high

[0004] 2. The longer operation time will cause the operator to be exposed to radiation for a longer time, and the risk is also greater

[0005] 3. The operation time is long, which is not conducive to the quality of the product; for example, the product 18F-FDG has a half-life of 105-115 minutes. With the extension of time, the product will decay quickly.

[0006] 4. If the device is not pre-installed and sterilized as a whole, it is difficult to ensure the sterility of the sampling device, resulting in false positives

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