Medicament for treating rheumatoid arthritis and preparation method of medicament

A technology for arthritis and rheumatoid arthritis, applied in the field of drugs and preparations for the treatment of rheumatoid arthritis, it can solve the problems of long course of medication, drug tolerance, failure to overcome RA, etc. short effect

Inactive Publication Date: 2015-06-03
GUIYANG COLLEGE OF TRADITIONAL CHINESE MEDICINE
View PDF7 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The short-term treatment of western medicine has a better effect on improving symptoms, but it cannot solve the fundamental problem
At the same time, long-term large-scale use of antibiotics is prone to drug tolerance, and the side effects of drugs are also relatively serious.
The range of commonly used Chinese medicines to treat rheumatism is too broad, so there is no obvious pertinence for the treatment of RA, the short-term curative effect is not satisfactory, and the treatment period of medication is long.
At this stage, the research on RA has become a focus and hot spot in the academic circle, and the research level has penetrated to the cellular level, molecular level, and even the gene level. However, due to the extremely complicated etiology of RA, the medical community has not yet overcome the worldwide problem of RA.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Medicament for treating rheumatoid arthritis and preparation method of medicament
  • Medicament for treating rheumatoid arthritis and preparation method of medicament
  • Medicament for treating rheumatoid arthritis and preparation method of medicament

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0108] Prescription: black bone vine 6kg, white peony 6kg, golden iron lock 1kg, Panax notoginseng 1kg.

[0109] Process: take the traditional Chinese medicinal materials, extract twice with 6 times the amount of 70% ethanol, 1.5 hours each time, combine the extracts, filter with a 200-mesh sieve, recover the ethanol from the filtrate, reduce it at -0.08Mpa, 75 ℃ The extract with a relative density of 1.32-1.35 when it was concentrated under pressure to 60°C, dried under reduced pressure at -0.08Mpa and 60°C, pulverized into powder, passed through an 80-mesh sieve, mixed with 25% of the prepared amount of mixing accessories, and mixed. The excipients are made by mixing microcrystalline cellulose and corn starch in a ratio of 1:1, granulated with 70% ethanol as a wetting agent, dried at 60 °C after granulation, and then sieved through a 12-mesh sieve once, and granulated with a 60-mesh sieve. The fine powder is sieved out, and the capsules are filled to obtain capsules.

[011...

Embodiment 2

[0112] Prescription: black bone vine 1kg, white peony 1kg, golden iron lock 0.5kg, Panax notoginseng 0.5kg.

[0113] Process: take the traditional Chinese medicinal materials, extract twice with 6 times the amount of 70% ethanol, 1.5 hours each time, combine the extracts, filter with a 200-mesh sieve, recover the ethanol from the filtrate, reduce it at -0.08Mpa, 75 ℃ The extract with a relative density of 1.32-1.35 when concentrated to 60°C, dried under reduced pressure at -0.08Mpa and 60°C, pulverized into powder, passed through an 80-mesh sieve, and added with 10% of dextrin and 10% of Aspartame, mixed evenly, granulated with 70% ethanol, and dried to obtain granules.

[0114] Dosage: Take with boiling water, 15g each time, 3 times a day.

Embodiment 3

[0116] Prescription: black bone vine 10kg, white peony 10kg, golden iron lock 5kg, Panax notoginseng 5kg.

[0117] Process: take the traditional Chinese medicinal materials, extract twice with 6 times the amount of 70% ethanol, 1.5 hours each time, combine the extracts, filter with a 200-mesh sieve, recover the ethanol from the filtrate, reduce it at -0.08Mpa, 75 ℃ The extract with a relative density of 1.32-1.35 when it was pressed and concentrated to 60°C, was dried under reduced pressure at -0.08Mpa and 60°C, pulverized into powder, passed through an 80-mesh sieve, added with 20% of starch and the amount of 3 % magnesium stearate, mix well, use 90% ethanol as a wetting agent to granulate, and press into tablets to obtain tablets.

[0118] Dosage: Oral, 3-5 tablets at a time, 3 times a day

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses a medicament for treating rheumatoid arthritis. The medicament is prepared from the following medicinal raw materials including forrest silkvine stems or roots and roots of tuniclike psammosilene. The medicament has the efficacies of expelling wind-damp, dispersing blood stasis and relieving pain, is used for RA syndromes caused by being affected by wind-cold-dampness, deficiency of liver, kidney, qi and blood, lingering pathogen due to deficient vital qi and mixed coldness and heat, is definite in curative effect, does not have toxic or side effect and is short in medication course.

Description

Field of Invention: [0001] The invention relates to a medicine for treating rheumatoid arthritis and a preparation method, and belongs to the technical field of traditional Chinese medicines. technical background: [0002] Rheumatoid arthritis (RA) is characterized by chronic, symmetrical, polysynovial arthritis and extra-articular lesions (subcutaneous nodules, pericarditis, pleurisy, pneumonia, peripheral neuritis, etc.) An autoimmune disease for which there is no specific diagnostic indicator. Its prominent clinical manifestations are recurrent symmetrical polyarthritis, with joints such as the hands, wrists, and feet most commonly affected, with redness, swelling, heat, pain and dysfunction in the early stage, and joints of varying degrees in the advanced stage. Toughness and deformity, as well as bone and skeletal muscle atrophy, is a disease with a high disability rate. Epidemiological survey results in my country show that the prevalence of RA is 0.35%, and female p...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/71A61P19/02A61P29/00
Inventor 李江童宏龙王文春陈秋霞
Owner GUIYANG COLLEGE OF TRADITIONAL CHINESE MEDICINE
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap