Preparation method of medical hemostatic occlusion dressing

Abstract

The invention discloses a preparation method of a medical hemostatic occlusion dressing. The preparation method comprises the following steps: (1), taking and pouring deionized water into a reactor, heating the reactor, slowly adding lemon peel pectin and gelatin, and mechanically stirring at the same time; (2), after the addition of the lemon peel pectin and gelatin, stirring continuously, then adding other components into the reactor, and carrying out mechanical stirring uniformly at the same time; (3), after the mixing of the materials, cooling hydrogel to be at a room temperature, so as to obtain the medical hemostatic occlusion dressing. The medical hemostatic occlusion dressing prepared through the method provided by the invention is high in bleeding stopping speed, has auxiliary functions of promoting wound surface healing, preventing adhesion and the like, is also better in biomechanics and air permeability, and has an important clinical application value; the preparation method provided by the invention has the advantages that the process is simple, requirements for equipment are relaxed, raw materials are low in cost and readily available, the cost is low, and industrialization is easy to realize.

Description

technical field

[0001] The invention belongs to the field of new medical materials and relates to a preparation method of a medical hemostatic occlusion dressing. technical background

[0002] Antibacterial hemostasis has always been a problem often encountered in hospital operations, and it is also a difficult problem often encountered in daily life. Medical dressing is a medical product used to cover burns, wounds, ulcers and other wounds, so that it temporarily plays a part of the skin barrier function, providing an environment conducive to wound healing, waiting for the epithelialization of the wound or transition to permanent reconstruction skin barrier. With the in-depth study of the pathophysiology of the wound healing process, people's understanding of the wound healing process is becoming more and more profound, thus promoting the continuous improvement and development of wound dressings. Today, new wound dressings have undergone revolutionary changes compared to ...

Examples

Embodiment 1

[0008] A method for preparing a medical hemostatic occlusive dressing, the preparation method comprising the following steps: (1) Take 20 parts by weight of deionized water and pour it into a reactor, heat the reactor to 76-85°C, and then slowly inject Add 13 parts by weight of lemon peel pectin and 15 parts by weight of gelatin, and mechanically stir while adding lemon peel pectin and gelatin; (2) After adding lemon peel pectin and gelatin, continue stirring for 10-15 minutes, and then add Add 10 parts by weight of chitosan, 3 parts by weight of jellyfish collagen, 4 parts by weight of sodium hyaluronate, 6 parts by weight of starch, 3 parts by weight of ammonium dihydrogen phosphate, 4 parts by weight of licorice extract, 3 parts by weight of camellia oil, nano 4 parts by weight of zinc oxide and 2 parts by weight of sodium alginate, while adding, mechanically stir evenly at a speed of 100-150r / min; (3) After the above materials are mixed, cool the hydrogel to room temperatur...

Embodiment 2

[0011] A method for preparing a medical hemostatic occlusive dressing, the preparation method comprising the following steps: (1) Take 30 parts by weight of deionized water and pour it into a reactor, heat the reactor to 76-85°C, and then slowly inject Add 15 parts by weight of lemon peel pectin and 18 parts by weight of gelatin, and mechanically stir while adding lemon peel pectin and gelatin; (2) After adding lemon peel pectin and gelatin, continue stirring for 10-15 minutes, and then add Add 14 parts by weight of chitosan, 6 parts by weight of jellyfish collagen, 8 parts by weight of sodium hyaluronate, 9 parts by weight of starch, 8 parts by weight of ammonium dihydrogen phosphate, 9 parts by weight of licorice extract, 7 parts by weight of camellia oil, nano 9 parts by weight of zinc oxide and 5 parts by weight of sodium alginate are added, and mechanically stirred evenly at the same time, the mechanical stirring speed is 100-150r / min; (3) After the above materials are mix...

Embodiment 3

[0014] A method for preparing a medical hemostatic occlusive dressing, the preparation method comprising the following steps: (1) Take 25 parts by weight of deionized water and pour it into a reactor, heat the reactor to 76-85°C, and then slowly inject Add 14 parts by weight of lemon peel pectin and 16 parts by weight of gelatin, and mechanically stir while adding lemon peel pectin and gelatin; (2) After adding lemon peel pectin and gelatin, continue stirring for 10-15 minutes, and then add Add 12 parts by weight of chitosan, 4 parts by weight of jellyfish collagen, 6 parts by weight of sodium hyaluronate, 7 parts by weight of starch, 6 parts by weight of ammonium dihydrogen phosphate, 6 parts by weight of licorice extract, 5 parts by weight of camellia oil, nano 6 parts by weight of zinc oxide and 3 parts by weight of sodium alginate, while adding, mechanically stir evenly at a speed of 100-150r / min; (3) After the above materials are mixed, cool the hydrogel to room temperatur...

technical field

[0001] The invention belongs to the field of new medical materials and relates to a preparation method of a medical hemostatic occlusion dressing. technical background

[0002] Antibacterial hemostasis has always been a problem often encountered in hospital operations, and it is also a difficult problem often encountered in daily life. Medical dressing is a medical product used to cover burns, wounds, ulcers and other wounds, so that it temporarily plays a part of the skin barrier function, providing an environment conducive to wound healing, waiting for the epithelialization of the wound or transition to permanent reconstruction skin barrier. With the in-depth study of the pathophysiology of the wound healing process, people's understanding of the wound healing process is becoming more and more profound, thus promoting the continuous improvement and development of wound dressings. Today, new wound dressings have undergone revolutionary changes compared to ...

Examples

Embodiment 1

[0008] A method for preparing a medical hemostatic occlusive dressing, the preparation method comprising the following steps: (1) Take 20 parts by weight of deionized water and pour it into a reactor, heat the reactor to 76-85°C, and then slowly inject Add 13 parts by weight of lemon peel pectin and 15 parts by weight of gelatin, and mechanically stir while adding lemon peel pectin and gelatin; (2) After adding lemon peel pectin and gelatin, continue stirring for 10-15 minutes, and then add Add 10 parts by weight of chitosan, 3 parts by weight of jellyfish collagen, 4 parts by weight of sodium hyaluronate, 6 parts by weight of starch, 3 parts by weight of ammonium dihydrogen phosphate, 4 parts by weight of licorice extract, 3 parts by weight of camellia oil, nano 4 parts by weight of zinc oxide and 2 parts by weight of sodium alginate, while adding, mechanically stir evenly at a speed of 100-150r / min; (3) After the above materials are mixed, cool the hydrogel to room temperatur...

Embodiment 2

[0011] A method for preparing a medical hemostatic occlusive dressing, the preparation method comprising the following steps: (1) Take 30 parts by weight of deionized water and pour it into a reactor, heat the reactor to 76-85°C, and then slowly inject Add 15 parts by weight of lemon peel pectin and 18 parts by weight of gelatin, and mechanically stir while adding lemon peel pectin and gelatin; (2) After adding lemon peel pectin and gelatin, continue stirring for 10-15 minutes, and then add Add 14 parts by weight of chitosan, 6 parts by weight of jellyfish collagen, 8 parts by weight of sodium hyaluronate, 9 parts by weight of starch, 8 parts by weight of ammonium dihydrogen phosphate, 9 parts by weight of licorice extract, 7 parts by weight of camellia oil, nano 9 parts by weight of zinc oxide and 5 parts by weight of sodium alginate are added, and mechanically stirred evenly at the same time, the mechanical stirring speed is 100-150r / min; (3) After the above materials are mix...

Embodiment 3

[0014] A method for preparing a medical hemostatic occlusive dressing, the preparation method comprising the following steps: (1) Take 25 parts by weight of deionized water and pour it into a reactor, heat the reactor to 76-85°C, and then slowly inject Add 14 parts by weight of lemon peel pectin and 16 parts by weight of gelatin, and mechanically stir while adding lemon peel pectin and gelatin; (2) After adding lemon peel pectin and gelatin, continue stirring for 10-15 minutes, and then add Add 12 parts by weight of chitosan, 4 parts by weight of jellyfish collagen, 6 parts by weight of sodium hyaluronate, 7 parts by weight of starch, 6 parts by weight of ammonium dihydrogen phosphate, 6 parts by weight of licorice extract, 5 parts by weight of camellia oil, nano 6 parts by weight of zinc oxide and 3 parts by weight of sodium alginate, while adding, mechanically stir evenly at a speed of 100-150r / min; (3) After the above materials are mixed, cool the hydrogel to room temperatur...