A traditional Chinese medicine compound against viral liver injury in ducks and rabbits
A technology for viral liver injury and traditional Chinese medicine, applied in antiviral agents, medical formulas, drug combinations, etc., can solve the problem of no available drugs for viral diseases, and achieve the effects of low cost, simple prescription, and simple preparation process
Active Publication Date: 2017-10-27
NANJING AGRICULTURAL UNIVERSITY
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Problems solved by technology
Veterinary clinical antiviral medicines are completely banned, resulting in the situation that there is no clinically available medicine for this kind of viral diseases
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[0017] 1. Preparation of traditional Chinese medicine compound
[0018] Take 400g of Chinese medicine Tianjihuang, 400g of Radix Paeoniae Alba, 180g of Radix Glycyrrhizae, 20g of Panax notoginseng, add 15 times the mass of water, decoct quickly to boiling with strong fire, change to slow fire and maintain boiling for 40 minutes, and collect the decoction; Add 15 times the quality of water, decoct as above, repeat 2 times, collect the decoction, filter the decoction with 4 layers of gauze, and concentrate to 1000mL, after standing overnight, take the supernatant, subpackage, and circulate steam to sterilize , and store in a cool place after cooling.
[0019] 2. Therapeutic effect and liver injury protection effect of Chinese medicine extract on DHV-1 challenged infected ducks
[0020] 180 3-day-old non-immune Cherry Valley ducks were randomly divided into 3 groups, 60 birds in each group, which were blank control group (BC group, fed alone), no treatment control group (VC grou...
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The invention relates to a traditional Chinese medicine compound for resisting duck and rabbit viral liver injury, and belongs to the technical field of Chinese veterinary medicine preparation. Combine Tianjihuang, Radix Paeoniae Alba, Panax notoginseng, and licorice in a certain proportion, add 15 times the mass of water, decoct repeatedly 3 times, concentrate the decoction, pack separately, and sterilize. Using the method of artificial poisoning, it was found that the mortality rates of duck viral hepatitis and rabbit viral hemorrhagic disease were respectively reduced by 22.2 and 30 percentage points compared with the control group without treatment, the course of the disease was shortened by 1 to 2 days, and the infection rate was significantly reduced. The virus content in the post-infection animals effectively alleviated the changes in biochemical indicators of liver damage and oxidative stress damage in ducks and rabbits caused by virus attack. The traditional Chinese medicine compound obtained in the present invention not only has a good therapeutic effect on duck viral hepatitis and rabbit viral hemorrhagic disease, but also effectively alleviates the liver damage of ducks and rabbits caused by these two virus infections, and the composition and preparation process are simple and the cost is low .
Description
1. Technical field [0001] The invention relates to a traditional Chinese medicine compound for resisting duck and rabbit viral liver injury, and belongs to the technical field of Chinese veterinary medicine preparation. 2. Background technology [0002] Duck virus hepatitis (DVH) is a disease caused by duck hepatitis virus (DHV) infection that spreads rapidly, has a high morbidity rate and is highly fatal. The virus was first isolated in 1949 and is now distributed worldwide. DHV mainly has three serotypes, DHV-1 and its mutant strains, Duck Astrovirus and DHV-3, among which DHV-1 is the most toxic and widely distributed, and mainly infects ducklings under 3 weeks old, with a fatality rate higher than 80%, even up to 100%, is one of the main pathogens that seriously endanger the duck industry. Rabbit hemorrhagic disease virus (RHD) is an acute, severe and highly contagious infectious disease caused by rabbit hemorrhagic disease virus (RHDV), commonly known as "rabbit plagu...
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IPC IPC(8): A61K36/71A61P1/16A61P31/14
Inventor 刘家国杜红旭杨净净张帅兵陈云熊文王德云胡元亮武毅
Owner NANJING AGRICULTURAL UNIVERSITY