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65results about How to "Reduces oxidative stress damage" patented technology

Clinical nutrient formulation special for sarcopenia and preparation method thereof

The invention provides a clinical nutrient formulation special for sarcopenia, comprising, by weight, 18-30 parts of proteins, 9-13 parts of fat, 40-52 parts of carbohydrates, 4-8 parts of dietary fibers, 0.6-1.2 parts of macro elements, 0.01-0.03 part of trace elements, 0.005-0.02 part of fat-soluble vitamins, 0.005-0.20 part of water-soluble vitamins, 0.2-1 part of dietary essences, 0.07-4 partsof medicinal and edible ingredients, 0.1-1 part of natural plant compounds, and 0.03-0.6 part of new resource foods. The invention also provides a preparation method of the clinical nutrient formulation special for sarcopenia. The clinical nutrient formulation special for sarcopenia herein can meet the demand of a patient with sarcopenia for comprehensive balanced nutrition, can also improve bodyquality of the patient with sarcopenia and promote myodynamia recovery and muscle regeneration.
Owner:上海奥医生物医药科技有限公司

Organ preservation solution and method for preparing same

ActiveCN102726366AAvoid damageDisadvantages of Avoiding PrecipitationDead animal preservationPhosphateArginine
The invention relates to an organ preservation solution and a method for preparing the same. The method comprises the following steps of: (1) adopting double buffer pairs of citric acids and phosphates to enable the PH value of a solution to be maintained in a range of 7.5 to 8; (2) adding active ingredients such as adenosine, L-arginine, tryptophan, ligustrazine hydrochloride, reduced glutathione and the like and keep the solution stable; (3) to maintain a hypertonic property of the preservation solution with an osmotic pressure of 350-380 mOsm/L, adopting trehalose and gluconolactone as impermeable substances to effectively prevent cellular edema; and (4) adopting polyethylene glycol with a large molecular weight as a colloidal substance to effectively prevent extracellular space from expanding. Compared with the prior art, the method employs raw materials which are all homemade medicinal components and meet the standards of national pharmacopoeia, and are cheap and free of incompatibility; the organ preservation solution prepared is a colorless and transparent liquid which has stable properties, and can be sterilized by high temperature and high pressure, stored at normal temperature or low temperature, and refrigerated, and thus preparation, transportation, storage and usage of the organ preservation liquid are all very easy and convenient.
Owner:SHANGHAI GENEXT MEDICAL TECH

Wheat germ protein source antioxidative peptide, and preparation method and application thereof

The invention relates to a wheat germ protein source antioxidative peptide, and a preparation method and an application thereof. The wheat germ protein source antioxidative peptide comprises sequences shown as SEQ ID NO.1 and SEQ ID NO.2. The preparation method comprises the steps of making fresh wheat germs into defatted wheat germ protein powder; hydrolysizing with an alkaline protease, inactivating enzyme, centrifuging at a high speed, subjecting supernatant to ultrafiltration so as to remove large molecular substances, freeze-drying filtrate to obtain a wheat germ protein hydrolysate, passing a wheat germ protein hydrolysate solution through a macroporous absorbent resin column and a gel filtration chromatography column successively, and collecting components with the strongest antioxidant activity being a target product. The preparation method is simple and efficient in process. The obtained wheat germ protein source antioxidative peptide has relatively high antioxidant activity, has relatively small molecular weight and definite amino acid sequence, can clear free radicals and alleviate oxidative stress injuries, can also be used for antioxidant dietary supplements, and has the advantages of wide raw material sources, high security, low cost and the like, and has wide application prospects in the fields of foods, medicines, etc.
Owner:JIANGNAN UNIV

Application of chlorogenic acid in preparation of medicines for treating parkinson disease

The invention discloses an application of chlorogenic acid in preparation of medicines for treating a parkinson disease. The chlorogenic acid is beneficial to reduction of the toxicity of substantia nigra and striatum neurons and activation of the autophagy activity of substantia nigra and striatum neurons in a midbrain, beneficial to adjustment of blood ketone content of a parkinson disease mice model, and beneficial to inhibition of apoptosis of substantia nigra cells in the parkinson disease mice model, and plays positive improvement and treatment roles in symptoms, pathology and the like of the parkinson disease.
Owner:SICHUAN JIUZHANG BIO TECH CO LTD

Application of lycopene in preparation of human semen cryoprotectant

The invention relates to an application of lycopene in preparation of a human semen cryoprotectant, belonging to the field of human semen cryoprotectants. The invention discloses an application of lycopene in the preparation of the human semen cryoprotectant. Every 100mL of the lycopene-containing human semen cryoprotectant comprises the following materials: 1.5g of glucose, 1.3g of trisodium citrate dehydrate, 20ml of glycerin, 4.296*10<-4>-4.296*10<-3>g of lycopene, 20ml of yolk, 0.01-0.1mL of dimethyl sulfoxide and the balance of double distilled water. A certain amount of lycopene is added into the cryoprotectant, so that the human semen cryopreservation effect is obviously improved, the functional parameters such as forward activity ratio and survival rate, of the thawed human semen are obviously higher than those in a control group in which the lycopene is not added, the normal morphology rate, DNA integrity rate and mitochondrial membrane potential are obviously higher than those in the control group, and the sperm apoptosis rate is obviously lower than that in the control group, so that the lycopene has high safety on human semen quality protection.
Owner:JILIN UNIV

Lactobacillus plantarum with protection function on stroke

The invention provides a lactobacillus plantarum AR113 strain with a protection function on stroke. The lactobacillus plantarum AR113 is preserved in the China General Microbiological Culture Collection Center on March 22, 2017, and the preservation number is CGMCCC No.13909. By adopting the lactobacillus plantarum AR113 strain provided by the invention is capable of improving antioxidant enzyme activities of brain tissue, reducing levels of oxidation products, activating Nrf-ARE signal channels, regulating relative expression amounts of antioxidation factors Nrf2, NQO01 and HO-1, meanwhile, reducing miRNA (micro ribonucleic acid) expression of apoptosis-promoting factors Cyt-C, Caspase-3 and Bax, increasing relative expression of an anti-apoptosis factor Bcl-2, and furthermore, relievingbran cell damage caused by cerebral ischemia reperfusion.
Owner:UNIV OF SHANGHAI FOR SCI & TECH

Application of ultra-small cerium oxide nanocrystal modified by phospholipid and polyethylene glycol

The invention relates to application of an ultra-small cerium oxide nanocrystal modified by phospholipid and polyethylene glycol, in particular to application of the ultra-small cerium oxide nanocrystal modified by the phospholipid and the polyethylene glycol in preparation of drugs for resisting acute liver injuries caused by acetaminophen. The ultra-small cerium oxide nanocrystal modified by thephospholipid and the polyethylene glycol can have various anti-oxidation mimic enzyme activities, and can effectively reduce the ultrahigh ROS level in the body, relieve inflammatory reactions and treat the acute liver injuries caused by APAP (N-acetyl-p-aminophenol).
Owner:ZHEJIANG UNIV

Hydrogel microcapsule for encapsulating nicotinic acid metal organic framework and preparation method and application thereof

The invention discloses a hydrogel microcapsule for encapsulating a nicotinic acid metal organic framework and a preparation method and application thereof. The preparation method of the hydrogel microcapsule for encapsulating the nicotinic acid metal organic framework comprises the steps that a nicotinic acid solution is used as an inner phase 1; a mixed solution of a zinc acetate solution and acopper acetate solution is used as an inner phase 2; a sodium alginate solution is used as an outer phase; and a microfluidic device is used for spraying mixed liquid drops of the inner phase 1 and the inner phase 2 wrapped by the outer phase into a calcium chloride solution to prepare the hydrogel microcapsule for encapsulating the nicotinic acid metal organic framework. The hydrogel microcapsulefor encapsulating the nicotinic acid metal organic framework, which is prepared by the invention, has ideal controlled release effect, antibacterial effect and anti-oxidative stress effect, and can be used for preparing wound healing materials or medical instruments.
Owner:NANJING GENERAL HOSPITAL NANJING MILLITARY COMMAND P L A

Mask for activating cell re-growth and awakening young state and preparation method thereof

The invention discloses a mask for activating cell re-growth and awakening young state and a preparation method thereof. The mask comprises the following raw materials: polyvinyl alcohol, vegetable hydrolyzed collagen, propylene glycol, sorbitol, tamaric acid, reuben oil, hydrogenated lecithin, xanthan gum, aloe gum, carbomer, sodium trehalose, dipotassium glycyrrhizinate, hydrolyzed silk protein,arginine, platinum powder, beta; dextran, resveratrol, sodium hyaluronate, benzalkonium hyaluronate, inositol hexaphosphate, silver oxide, volcanic rock powder, diatomite, tetrasodium pyrophosphate,pure water, fatty acid polyoxyethylene ether, algal fiber, tea powder, ganoderma lucidum, 4-methyl hydroxybenzoate, vitamin E and antibacterial modifying agent, wherein the mask for activating the cell to grow again and awakening the young state is obtained through the steps of preparing material A, preparing material B, preparing mixture, sterilizing the mixture, and the like. The mask has excellent antibacterial effect.
Owner:长沙浩然医疗科技有限公司

Edible bird's nest composition having efficacy of resisting ageing and preparation method and application of edible bird's nest composition

The application of the invention discloses an edible bird's nest composition having efficacy of resisting ageing and a preparation method and application of the edible bird's nest composition. The edible bird's nest composition comprises the following components in parts by mass of 1-10 parts of edible bird's nest products, 100-500 parts of oligosaccharide, 0-100 parts of antioxidation components,1-10 parts of elastin peptide and 200-800 parts of cartilage collagen peptide or fish skin collagen peptide. According to the edible bird's nest composition disclosed by the invention, the problem that conventional edible bird's nest products are poor in the function of resisting ageing is solved.
Owner:杭州玖拾伍度鲜生物科技有限公司 +1

Traditional Chinese medicine composition for treating parkinson disease

The invention discloses a traditional Chinese medicine composition for treating Parkinson disease. The composition is prepared from 6-15g of cistanche and 6-12g of rhizoma acori graminei, wherein the effect of cistanche in relieving body oxidative stress injury and eliminating free radicals is utilized and is combined with the effect of the rhizoma acori graminei in improving permeability of blood brain barrier to prepare powder, granules, electuary or other traditional Chinese medicine preparations for treating Parkinson disease. Experiments prove that the composition can be used for repairing injured dopaminergic neurons, effectively increasing the content of dopamine in substantia nigra-striatum, up-regulating expression of dopaminergic neurons TH, reducing the degree of brain tissue lipid peroxidation, increasing the antioxidative level in brain and reducing apoptosis of dopaminergic neuron of MPP+ induced Parkinson disease model MES23.5, and does not have remarkable toxins.
Owner:FUJIAN UNIV OF TRADITIONAL CHINESE MEDICINE

Application of Cordyceps sobolifera water extract in preparation of acute liver injury preventing and treating drug

InactiveCN106692208AAlleviate acute liver injuryAlleviate hepatic inflammatory response and prevent acute liver injuryAnthropod material medical ingredientsDigestive systemInflammatory factorsNeutrophil granulocyte
The invention belongs to the field of traditional Chinese medicine production and relates to an application of Cordyceps sobolifera water extract in preparation of an acute liver injury preventing and treating drug. Based on D-galactosamine / lipopolysaccharide induced acute liver injury model experiments, results prove that the Cordyceps sobolifera water extract can relieve lipid peroxidation and oxidative stress injury of liver cells by reducing transaminase (AST and ALT) and alkaline phosphatase (ALP) in serum, remarkably relieves infiltration of inflammatory factors of the liver and improves liver lesion obviously, meanwhile, the Cordyceps sobolifera water extract can relieve infiltration of neutrophils in the liver, inhibit transcription and expression of related inflammatory mediators, reduce inflammation induced inflammatory factor and NO release and inhibit MAPK (mitogen-activated protein kinases) pathway activation. The Cordyceps sobolifera water extract can be used for preparing the acute liver injury preventing and treating drug and is used for protecting liver function and relieving liver inflammation.
Owner:FUDAN UNIV

Support material with conductivity and antioxygenic property and preparation method thereof

The invention discloses a support material with conductivity and an antioxygenic property and a preparation method thereof. The support material is prepared from phenylamine pentamer modified by glutathione, and gelatin. The support material has favorable mechanical strength and adjustable degradation characteristic. More importantly, the support material has good conductivity, and can effectively scavenge various oxygen radicals such as hydroxyl radicals, organic oxygen radicals and superoxide radicals. According to the support material with the conductivity and the antioxygenic property and the preparation method thereof provided by the invention, the dual-network conductive support material is prepared by adopting one-step shaping, so that the preparation method is simple, components are uniform and controllable. More importantly, the support material has favorable biocompatibility and can support the adhesion and the growth of various cells. Stem cells can be promoted to differentiate into cardiac muscle cells, so that the support material has potential application prospect in cardiac muscle tissue engineering.
Owner:INST OF BASIC MEDICAL SCI ACAD OF MILITARY MEDICAL SCI OF PLA

Application of coniferyl aldehyde in preparation of medicine for treating neonatal necrotizing enterocolitis

InactiveCN113181144AClear interventionReduces oxidative stress damageDigestive systemAldehyde active ingredientsNeonatal necrotising enterocolitisPharmaceutical drug
The invention belongs to the field of biological medicines, and particularly relates to application of coniferyl aldehyde in the preparation of a medicine for treating neonatal necrotizing enterocolitis. The coniferyl aldehyde provided by the invention inhibits an HMGB1 transcription function by activating an Nrf2 / HO-1 pathway, and alleviates oxidative stress injury of intestinal epithelial cells, so that the neonatal necrotizing enterocolitis is improved. The effect of the Nrf2 / HO-1 / HMGB1 pathway in NEC intestinal epithelial cell oxidative damage and the intervention effect of coniferyl aldehyde are defined, and a new strategy is provided for prevention and treatment of neonatal necrotizing enterocolitis.
Owner:WUXI MATERNAL & CHILD HEALTH HOSPITAL

Application of dihydrocurcumin in the preparation of medicine for treating non-alcoholic fatty liver diseases

The invention discloses an application of dihydrocurcumin in the preparation of a medicine for treating non-alcoholic fatty liver diseases. In vitro cell experiments showed that (1) the dihydrocurcumin reduces the TG content in hepatocytes and improves hepatic lipid metabolism by decreasing expression of SREBP-1C, PNPLA3 mRNA and protein in the hepatocytes and increasing expression of PPARa mRNA and protein, (2) the dihydrocurcumin increases expression of PI3K / AKT in the hepatocytes and improves the ability of the hepatocytes to absorb glucose so as to enhance the insulin sensitivity, (3) thedihydrocurcumin reduces the ROS content so as to improve oxidative stress by increasing expression of Nrf2 protein in the hepatocytes and decreasing expression of CYP4A, and (4) the dihydrocurcumin alleviates inflammation by reducing the NO content in the hepatocytes. Therefore, the dihydrocurcumin is an excellent candidate medicine for the treatment of the non-alcoholic fatty liver diseases.
Owner:HUBEI UNIV

Application of andrographolide derivatives in preparing medicaments for preventing and treating neurodegenerative diseases

The invention belongs to the technical field of medicines, and discloses an application of andrographolide derivatives in preparing medicaments for preventing and treating neurodegenerative diseases. The andrographolide derivatives are andrographolide derivatives AL-1 prepared from andrographolide and alpha-lipoic acid. In-vivo and in-vitro testing results indicate that the AL-1 has an effect of protecting nerves, and can be used for improving the behavioristics of a Parkinson disease model mouse; the mechanism of an AL-1 nerve protection effect is related to free radical scavenging, oxidation resistance and nuclear transcription factor kB(NF-kB) inactivation inhibition. Therefore, the andrographolide derivative AL-1 can be used as a medicament for preventing and treating neurodegenerative diseases, in particular Parkinson disease, and can be manufactured into various preparations with available medicinal carriers.
Owner:JINAN UNIVERSITY

Self-heating type temperature partition maintenance instrument

The invention discloses a self-heating type temperature partition maintenance instrument. The instrument comprises a hot compress disc, a second handle is arranged at the upper end of the hot compressdisc; a plurality of feeding pipes are arranged in the hot compress disc, a cover plate for sealing the feeding pipes is arranged at the upper ends of the feeding pipes, a first handle is arranged onthe cover plate, a feeding cavity is formed in each feeding pipe, each feeding cavity is filled with a grid, a heating bag is arranged above each grid, a first sponge layer is arranged at the lower end of each heating bag, and the space between each first sponge layer and the corresponding grid is filled with a medicine layer. The self-heating type temperature partition maintenance instrument prepared by the invention has excellent antibacterial and water supplementing properties.
Owner:刘敏

Substance content determination method and application thereof

ActiveCN111366680AExpanding the scope of clinical medicine to treat diseasesGood treatment effectNervous disorderComponent separationDiseaseAngelica Sinensis Root
The invention relates to a substance content determination method and an application thereof. The substance is prepared from 225 parts of astragalus membranaceus, 100 parts of leech, 90 parts of ligusticum wallichii, 90 parts of angelica sinensis, 90 parts of safflower carthamus, 113 parts of peach kernel, 90 parts of radix paeoniae rubra, 90 parts of elecampane, 90 parts of rhizoma acori graminei, 60 parts of lumbricus, 90 parts of parasitic loranthus and 35 parts of acanthopanax extract. The content detection method has characteristics of simple and rapid operation and good repeatability andaccuracy. The method is advantaged in that pharmacological experiments of the substance show that the substance can significantly improve the mouse behavior coordination ability, significantly shorten the mouse pole climbing time, enhance the mouse grabbing force and the mouse swimming time, and significantly relieve MPTP-induced neuron damage, the substance content determination method can effectively control the inherent quality of the drug, and the new treatment application of the substance enlarges the clinical medication disease treatment range of the drug.
Owner:SHAANXI BUCHANG PHARMA

Traditional Chinese medicine compound resisting duck and rabbit viral liver damage

The invention relates to a traditional Chinese medicine compound resisting duck and rabbit viral liver damage, belonging to the technical field of preparation of traditional Chinese veterinary medicines. The traditional Chinese medicine compound resisting the duck and rabbit viral liver damage is prepared by the following steps of combining herba hyperici japonica, white paeony root, pseudo-ginseng and liquorice according to a certain ratio; adding water in an amount which is 15 times the mass of the mixture; repeatedly decocting for three times; concentrating the decoction solution; and subpackaging and sterilizing. An artificial infection method discovers that after the compound is applied, the death rate of ducks suffering from viral hepatitis and the death rate of rabbits suffering from viral hemorrhagic disease are respectively reduced by 22.2% and 30% compared with those of the non-treatment control groups, the course of diseases is shortened by 1 to 2 days, the content of viruses in the animals after counteraction to toxic substances is obviously reduced, and the change of duck and rabbit liver damage biochemical indexes and oxidative stress injury caused by virus attack are effectively reduced. The traditional Chinese medicine compound has a good treatment effect on duck viral hepatitis and rabbit viral hemorrhagic disease, effectively reduces duck and rabbit liver damage caused by infection of the two viruses, and is simple in component and preparation process and low in cost.
Owner:NANJING AGRICULTURAL UNIVERSITY

Preparation method of thermally responsive bladder extracellular matrix bioactive hydrogel

The invention discloses a preparation method of a thermally responsive bladder extracellular matrix bioactive hydrogel, relates to the field related to bioactive hydrogel preparation methods, and solves the problems that most of existing methods for obtaining an extracellular matrix (ECM) in the prior art have the defects of insufficient elution and large damage to ECM, and preparation of bladder-derived ECM hydrogels has not been reported so far. The preparation method comprises the following steps: step 1: taking a fresh pig bladder, keeping the ureter and urethral structure, and conductingrinsing with 3000 mL of double distilled water for 2 h; step 2: after wrapping by tin foil paper, quickly place the wrapped object in a refrigerator of -80 DEG C for 1 hour, then taking the object outand balancing the object to room temperature; step 3: repeating the step two for two times; step 4: conducting perfusion and immersing by double distilled water for 4 h, and immersing the whole bladder in a perfusate; and step 5: conducting perfusion and immersing by 1% Triton X-100 for 4 h, and immersing the whole bladder in a 1% Triton X-100 perfusate, and then conducting rinsing by double distilled water for 20 min.
Owner:NANJING FIRST HOSPITAL

Anti-oxidative magnetic iron oxide nanoparticles and preparation method thereof

The invention discloses anti-oxidative magnetic iron oxide nanoparticles which comprise magnetic mesoporous silicon dioxide nanoparticles with a core-shell structure formed by coating the surface of an Fe3O4 inner core with mesoporous silicon dioxide, and also comprise an antioxidant N-acetylcysteine, wherein the antioxidant N-acetylcysteine is supported in mesoporous silicon dioxide. The invention also provides a preparation method of the anti-oxidative magnetic iron oxide nanoparticles. The method comprises the steps of preparing an antioxidant N-acetylcysteine solution; weighing a magneticmesoporous silicon dioxide nanoparticle solution with the core-shell structure, executing centrifugation, then adding the antioxidant N-acetylcysteine solution; sealing with a sealing film after ultrasonic treatment, placing the solution into a shaking table to shake, taking out a sample after completion, and centrifuging and drying the sample to obtain the anti-oxidative magnetic iron oxide nanoparticles. After the anti-oxidative magnetic iron oxide nanoparticles reach a target part, the antioxidant is released, so that the oxidative stress damage mediated by the iron oxide is relieved, and the histocompatibility of the magnetic iron oxide nanoparticles is improved.
Owner:SHANGHAI EAST HOSPITAL EAST HOSPITAL TONGJI UNIV SCHOOL OF MEDICINE

Preparation of lipoic acid-loaded nano material and application of lipoic acid-loaded nano material in acute myocardial infarction disease

The invention belongs to the technical field of biochemical medicines, and particularly relates to preparation of a lipoic acid-loaded nano-material and application of the lipoic acid-loaded nano-material in acute myocardial infarction diseases. An electrospinning technology is adopted, and a multi-layer lipoic acid-loaded PLGA nano-film material is synthesized by taking PLGA which is degraded at a controllable speed as a raw material to load lipoic acid; the nano-film material has better drug loading capacity and encapsulation efficiency, and also has a better drug release effect in a PBS (Phosphate Buffer Solution), so that the drug can be quickly and continuously released locally in a myocardial infarction area, and a good anti-oxidative stress treatment effect is achieved; when being applied to myocardial infarction treatment (namely being placed on the surface of myocardial infarction heart tissue in a pericardial cavity) as a cardiac functional patch, the medicine can improve ventricular remodeling, improve the cardiac function level, effectively relieve myocardial cell oxidative stress injury and improve the treatment effect of acute myocardial infarction.
Owner:THE THIRD AFFILIATED HOSPITAL OF SUN YAT SEN UNIV

Hydrophilic nano-drug carrying beta-carotene and application thereof in preparation of drug for treating cerebral ischemia-reperfusion injury

The invention belongs to the technical field of medicines, and particularly relates to a hydrophilic nano-drug carrying beta-carotene and an application thereof in preparation of a drug for treating cerebral ischemia-reperfusion injury. According to the invention, the beta-carotene is carried by the high-molecular DSPE-PEG, so that the water solubility and the stability of the high-molecular DSPE-PEG are improved; an intrathecal injection method is used for increasing the aggregation of the nano-drug in the brain; beta-carotene is used for removing active oxygen, oxidative stress injury afterischemia-reperfusion of the brain is effectively reduced, the important value is achieved for developing medical application of beta-carotene, and the important significance is achieved for treating and relieving ischemia-reperfusion injury of the brain.
Owner:THE SECOND AFFILIATED HOSPITAL TO NANCHANG UNIV

Medicine for treating non-alcoholic steatohepatitis

The invention belongs to the field of medicines and provides a medicine for treating non-alcoholic steatohepatitis (NASH). A compound kinsenoside (3-(R)-3-beta-D-glucopyranosyloxbutanolide has a good treatment effect on NASH of mice induced by using an MCD feed (methionine-choline-deficient feed), can effectively reduce liver fat accumulation, relieve liver injury, reduce inflammatory infiltration and oxidative stress injury, and reduce expression of fibrosis marker gene and protein so as to prevent NASH from developing to hepatic fibrosis, indicating that the kinsenoside can be used as a medicine for treating NASH.
Owner:HUAZHONG UNIV OF SCI & TECH

Negative pressure treatment wound surface patch containing metal ion antibacterial agent and preparation method for patch

InactiveCN102430146AAntibacterial tissue cell oxidative stress damageReduce tissue cell oxidative stress damageAdhesive dressingsAbsorbent padsIonWoven fabric
The invention relates to a wound surface patch which contains a metal ion antibacterial agent, is used for closed negative pressure treatment of a wound surface and has antibacterial and tissue repair promoting effects, and a preparation method for the patch. The wound surface patch comprises a sponge layer, a negative pressure suction tube which stretches into the sponge layer, and a non-woven fabric combined with the sponge layer. The invention provides the negative pressure treatment wound surface patch which contains the metal ion antibacterial agent and ensures that negative pressure drainage is effectively implemented and antibacterial and tissue healing promoting comprehensive treatment effects are achieved simultaneously so as to improve the treatment effect of chronic and refractory wound surfaces such as diabetic ulcer and the like, and the preparation method for the patch.
Owner:FOURTH MILITARY MEDICAL UNIVERSITY

Natural composition capable of improving liver function and preventing osteoporosis and preparation method of natural composition

The invention provides a natural composition capable of improving liver function and preventing osteoporosis. The natural composition consists of a radix bupleuri extract, a radix angelica sinensis extract, a nutgrass galingale rhizome extract, a dried orange peel extract, a fructus gardeniae extract, a maca extract and a licorice root extract, the effective components of the components interact, and can restrain rising of serum globulin, alanine aminotransferase and aspartic transaminase (AST) and reduction of albumin, the liver function can be improved, the content of bone minerals of bone density, bone calcium, bone phosphorus and the like can be increased, and the effect of relieving osteoporosis can be achieved.
Owner:EZHOU INST OF IND TECH HUAZHONG UNIV OF SCI & TECH +1

Application of oligosaccharide

The invention provides the application of oligosaccharide, and particularly discloses the application of oligosaccharide alpha-L-Rhap(1->4)->alpha-D-Galp serving as an acetaldehyde dehydrogenase activating agent, serving as a liver protective agent and in preparation of drugs for treating alcoholic liver diseases.
Owner:XIANGTAN UNIV

Cell cryopreservation kit and application method thereof

The invention provides a cell cryopreservation kit which comprises a first cryopreservation mother solution and a second cryopreservation mother solution, wherein the first cryopreservation mother solution contains a bilberry extract with the concentration of 90 g / L to 110 g / L, hydroxyethyl starch with the concentration of 90 g / mL to 110 g / L and dextran 40 with the concentration of 180 g / L to 220 g / L; and the second cryopreservation mother solution contains proline with the concentration of 90 g / mL to 110 g / mL, human serum albumin with the concentration of 180 g / mL to 220 g / mL and dextran 40 with the concentration of 270 g / mL to 330 g / mL. The bilberry extract and the proline are adopted as main raw materials, oxidative stress damage to cells caused by ice crystal formation in the cell cryopreservation process is effectively reduced, the cell viability, the form, the multiplication capacity and the differentiation potential of the cryopreserved cells can be maintained, the biological activity of the cryopreserved cells is maintained, the cryopreservation algebra is prolonged, and the biological safety and the compatibility are improved.
Owner:北京京蒙细胞生物科技股份有限公司
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